Diabetic Angiopathies Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

135 genes associated with the Diabetic Angiopathies phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACE angiotensin I converting enzyme
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADD1 adducin 1 (alpha)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB1 adrenoceptor beta 1
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHSG alpha-2-HS-glycoprotein
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOA1 apolipoprotein A-I
APOA4 apolipoprotein A-IV
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
ARMS2 age-related maculopathy susceptibility 2
C10ORF107 chromosome 10 open reading frame 107
CAT catalase
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2B-AS1 CDKN2B antisense RNA 1
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CNR1 cannabinoid receptor 1 (brain)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYBA cytochrome b-245, alpha polypeptide
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DRD1 dopamine receptor D1
EDN1 endothelin 1
F12 coagulation factor XII (Hageman factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FGB fibrinogen beta chain
FN3K fructosamine 3 kinase
FTO fat mass and obesity associated
GAS6 growth arrest-specific 6
GCH1 GTP cyclohydrolase 1
GHRL ghrelin/obestatin prepropeptide
GLO1 glyoxalase I
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPX1 glutathione peroxidase 1
GRK4 G protein-coupled receptor kinase 4
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
HHEX hematopoietically expressed homeobox
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HP haptoglobin
ICAM1 intercellular adhesion molecule 1
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IGFBP1 insulin-like growth factor binding protein 1
IL6 interleukin 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF6 kinesin family member 6
LEPR leptin receptor
LIPC lipase, hepatic
LIPG lipase, endothelial
LPA lipoprotein, Lp(a)
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene
LPL lipoprotein lipase
MBL2 mannose-binding lectin (protein C) 2, soluble
MC4R melanocortin 4 receptor
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAMPT nicotinamide phosphoribosyltransferase
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5C2 5'-nucleotidase, cytosolic II
PARL presenilin associated, rhomboid-like
PCSK9 proprotein convertase subtilisin/kexin type 9
PEMT phosphatidylethanolamine N-methyltransferase
PHACTR1 phosphatase and actin regulator 1
PLG plasminogen
PON1 paraoxonase 1
PON2 paraoxonase 2
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCB protein kinase C, beta
PSRC1 proline/serine-rich coiled-coil 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
REN renin
RETN resistin
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD7 SET domain containing (lysine methyltransferase) 7
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORT1 sortilin 1
SUMO4 small ubiquitin-like modifier 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIMP VCP-interacting membrane selenoprotein
VKORC1 vitamin K epoxide reductase complex, subunit 1
VWF von Willebrand factor