Diabetic Angiopathies Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D003925
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Genes

114 genes/proteins associated with the disease Diabetic Angiopathies from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 2.88009
HP haptoglobin 2.88009
NOS3 nitric oxide synthase 3 (endothelial cell) 2.88009
ALB albumin 2.88009
AGER advanced glycosylation end product-specific receptor 2.88009
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 2.88009
ASS1 argininosuccinate synthase 1 2.88009
CYBA cytochrome b-245, alpha polypeptide 1.75301
PPARA peroxisome proliferator-activated receptor alpha 1.69951
TGFB1 transforming growth factor, beta 1 1.69721
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.63227
CAT catalase 1.56214
LEP leptin 1.56019
ADIPOQ adiponectin, C1Q and collagen domain containing 1.50953
VEGFA vascular endothelial growth factor A 1.4612
NOS2 nitric oxide synthase 2, inducible 1.45009
ICAM1 intercellular adhesion molecule 1 1.41063
CCL2 chemokine (C-C motif) ligand 2 1.40148
IL1B interleukin 1, beta 1.38696
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.3827
PPARG peroxisome proliferator-activated receptor gamma 1.37619
MAPK3 mitogen-activated protein kinase 3 1.36791
IL6 interleukin 6 1.35676
LIPE lipase, hormone-sensitive 1.35618
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.35415
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.34576
INS insulin 1.32251
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.31357
CAV1 caveolin 1, caveolae protein, 22kDa 1.31237
SCARB1 scavenger receptor class B, member 1 1.31089
GSK3B glycogen synthase kinase 3 beta 1.30788
ACE angiotensin I converting enzyme 1.30696
TNF tumor necrosis factor 1.30666
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.27751
VCAM1 vascular cell adhesion molecule 1 1.27132
MMP9 matrix metallopeptidase 9 1.26298
CTGF connective tissue growth factor 1.2599
CD36 CD36 molecule (thrombospondin receptor) 1.25682
APOA1 apolipoprotein A-I 1.25432
NOX4 NADPH oxidase 4 1.25369
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.25276
APOE apolipoprotein E 1.25121
MAPK1 mitogen-activated protein kinase 1 1.24874
EDN1 endothelin 1 1.2368
MPO myeloperoxidase 1.23201
FASN fatty acid synthase 1.22501
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.22145
ACTA2 actin, alpha 2, smooth muscle, aorta 1.21402
MMP2 matrix metallopeptidase 2 1.21076
THBS1 thrombospondin 1 1.20328
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.2013
NPPB natriuretic peptide B 1.19574
IRS1 insulin receptor substrate 1 1.18948
IFNG interferon, gamma 1.18652
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.18226
COL3A1 collagen, type III, alpha 1 1.18226
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.18226
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.18059
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.17959
BCL2 B-cell CLL/lymphoma 2 1.17794
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.17629
NCF1 neutrophil cytosolic factor 1 1.17202
BCL2L1 BCL2-like 1 1.17
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.16933
SOD1 superoxide dismutase 1, soluble 1.16833
FGF21 fibroblast growth factor 21 1.16335
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.16104
TIMP1 TIMP metallopeptidase inhibitor 1 1.15763
CPT1A carnitine palmitoyltransferase 1A (liver) 1.15695
NRF1 nuclear respiratory factor 1 1.15055
RETN resistin 1.14575
LITAF lipopolysaccharide-induced TNF factor 1.14098
TFAM transcription factor A, mitochondrial 1.13381
COL1A1 collagen, type I, alpha 1 1.13075
SIRT1 sirtuin 1 1.12323
ADIPOR1 adiponectin receptor 1 1.11639
PRKCA protein kinase C, alpha 1.11639
VDAC1 voltage-dependent anion channel 1 1.11186
CRP C-reactive protein, pentraxin-related 1.11081
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.10596
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.10388
FASLG Fas ligand (TNF superfamily, member 6) 1.08975
GCG glucagon 1.08833
SREBF1 sterol regulatory element binding transcription factor 1 1.08549
SOD2 superoxide dismutase 2, mitochondrial 1.08126
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.08055
BZW1 basic leucine zipper and W2 domains 1 1.07589
INSR insulin receptor 1.07163
HSPB1 heat shock 27kDa protein 1 1.06844
POR P450 (cytochrome) oxidoreductase 1.06552
CCNE1 cyclin E1 1.0608
G6PC glucose-6-phosphatase, catalytic subunit 1.05237
GSTA2 glutathione S-transferase alpha 2 1.05126
PPARD peroxisome proliferator-activated receptor delta 1.04904
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.04611
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.04574
GYS2 glycogen synthase 2 (liver) 1.04465
PDGFB platelet-derived growth factor beta polypeptide 1.04314
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.04163
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.04126
FN1 fibronectin 1 1.04014
MAPK14 mitogen-activated protein kinase 14 1.03901
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.03752
PRKCB protein kinase C, beta 1.03678
ADRB1 adrenoceptor beta 1 1.03046
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.03009
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.02858
APLN apelin 1.02783
APOB apolipoprotein B 1.02596
KEAP1 kelch-like ECH-associated protein 1 1.02262
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.01474
TMSB4X thymosin beta 4, X-linked 1.01474
ANGPT2 angiopoietin 2 1.01361
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.01099