Dementia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior. (Human Disease Ontology, DOID_1307)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D003704
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Genes

460 genes/proteins associated with the disease Dementia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
APP amyloid beta (A4) precursor protein 2.88009
TREM2 triggering receptor expressed on myeloid cells 2 2.88009
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.88009
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.88009
MAPT microtubule-associated protein tau 2.88009
GRN granulin 2.88009
DNMT1 DNA (cytosine-5-)-methyltransferase 1 2.88009
CP ceruloplasmin (ferroxidase) 2.88009
TNF tumor necrosis factor 2.27901
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.25466
BCL2 B-cell CLL/lymphoma 2 2.16697
TP53 tumor protein p53 2.14265
CAT catalase 2.13867
MAPK3 mitogen-activated protein kinase 3 2.13261
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.13114
IFNG interferon, gamma 2.08728
MAPK1 mitogen-activated protein kinase 1 2.08428
FOS FBJ murine osteosarcoma viral oncogene homolog 2.06772
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.02115
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.9988
BAX BCL2-associated X protein 1.99639
PRL prolactin 1.96506
CCL2 chemokine (C-C motif) ligand 2 1.96224
IL6 interleukin 6 1.94296
BDNF brain-derived neurotrophic factor 1.94015
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.93072
IL1B interleukin 1, beta 1.92595
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.91846
JUN jun proto-oncogene 1.91732
SOD2 superoxide dismutase 2, mitochondrial 1.90738
HMOX1 heme oxygenase 1 1.90425
NOS2 nitric oxide synthase 2, inducible 1.89042
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.86253
EGR1 early growth response 1 1.85011
TH tyrosine hydroxylase 1.84658
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.8113
GJA1 gap junction protein, alpha 1, 43kDa 1.79789
NFE2L2 nuclear factor, erythroid 2-like 2 1.79292
GSK3B glycogen synthase kinase 3 beta 1.77433
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.77199
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.75915
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.7552
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.72696
TAGLN transgelin 1.71214
INS insulin 1.71193
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.70968
MAP2 microtubule-associated protein 2 1.69825
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.69254
IL2 interleukin 2 1.69211
SOD1 superoxide dismutase 1, soluble 1.6774
DDIT3 DNA-damage-inducible transcript 3 1.67051
GSTA2 glutathione S-transferase alpha 2 1.65886
VCAM1 vascular cell adhesion molecule 1 1.64797
IL12B interleukin 12B 1.64551
FSHB follicle stimulating hormone, beta polypeptide 1.64484
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.63608
MBP myelin basic protein 1.61529
IL1A interleukin 1, alpha 1.61318
TGFB1 transforming growth factor, beta 1 1.60874
DUSP1 dual specificity phosphatase 1 1.60151
GADD45A growth arrest and DNA-damage-inducible, alpha 1.5816
VEGFA vascular endothelial growth factor A 1.57426
MAPK9 mitogen-activated protein kinase 9 1.57329
THBS1 thrombospondin 1 1.56533
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.56044
MAPK8 mitogen-activated protein kinase 8 1.55157
ALB albumin 1.54523
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 1.54402
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.53184
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.53036
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.52914
TFRC transferrin receptor 1.51759
IGF1 insulin-like growth factor 1 (somatomedin C) 1.50675
SPP1 secreted phosphoprotein 1 1.50574
TIMP1 TIMP metallopeptidase inhibitor 1 1.50473
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.49533
MMP3 matrix metallopeptidase 3 1.49508
CXCL8 chemokine (C-X-C motif) ligand 8 1.48838
LHB luteinizing hormone beta polypeptide 1.48684
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.48582
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.48273
EGFR epidermal growth factor receptor 1.48248
NOS3 nitric oxide synthase 3 (endothelial cell) 1.48248
S100A9 S100 calcium binding protein A9 1.48222
MMP2 matrix metallopeptidase 2 1.48068
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.46515
RGS2 regulator of G-protein signaling 2 1.46515
IGFBP3 insulin-like growth factor binding protein 3 1.46409
MMP9 matrix metallopeptidase 9 1.46409
DRD2 dopamine receptor D2 1.4633
PRKCE protein kinase C, epsilon 1.46304
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.46198
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.4591
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.45697
LDLR low density lipoprotein receptor 1.45643
GSTM1 glutathione S-transferase mu 1 1.45484
FN1 fibronectin 1 1.45458
NQO1 NAD(P)H dehydrogenase, quinone 1 1.45036
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.44517
CTGF connective tissue growth factor 1.43646
FAS Fas cell surface death receptor 1.43537
DRD4 dopamine receptor D4 1.43455
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.43347
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.43347
GPX1 glutathione peroxidase 1 1.4332
CCND3 cyclin D3 1.43293
ACO2 aconitase 2, mitochondrial 1.43076
COL3A1 collagen, type III, alpha 1 1.42723
NPY neuropeptide Y 1.42535
C10ORF10 chromosome 10 open reading frame 10 1.42293
MAOA monoamine oxidase A 1.41965
GSTP1 glutathione S-transferase pi 1 1.41613
MPO myeloperoxidase 1.41532
NUPR1 nuclear protein, transcriptional regulator, 1 1.41229
CCND1 cyclin D1 1.4012
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.39451
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.39254
FASN fatty acid synthase 1.39058
HSPA1A heat shock 70kDa protein 1A 1.38918
HSPB1 heat shock 27kDa protein 1 1.38807
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.38355
CTSD cathepsin D 1.38242
ACHE acetylcholinesterase (Yt blood group) 1.37958
CCNB1 cyclin B1 1.37275
COL1A1 collagen, type I, alpha 1 1.37075
CCL3 chemokine (C-C motif) ligand 3 1.36876
EGR2 early growth response 2 1.36763
GSTA4 glutathione S-transferase alpha 4 1.36247
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.35991
CDK2 cyclin-dependent kinase 2 1.35502
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.35386
CFL1 cofilin 1 (non-muscle) 1.35069
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.35069
MYB v-myb avian myeloblastosis viral oncogene homolog 1.35069
PDGFB platelet-derived growth factor beta polypeptide 1.35012
COMT catechol-O-methyltransferase 1.3484
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.34606
GCLC glutamate-cysteine ligase, catalytic subunit 1.34547
PRKCB protein kinase C, beta 1.34198
NGFR nerve growth factor receptor 1.3385
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.33346
MME membrane metallo-endopeptidase 1.33257
BCL2L1 BCL2-like 1 1.33257
CREB1 cAMP responsive element binding protein 1 1.3311
ALDOC aldolase C, fructose-bisphosphate 1.32964
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.32964
CDKN2A cyclin-dependent kinase inhibitor 2A 1.32696
IL10 interleukin 10 1.3228
IL18 interleukin 18 1.31837
AFP alpha-fetoprotein 1.31
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.30329
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.29966
UNG uracil-DNA glycosylase 1.2941
TNC tenascin C 1.2941
ADIPOQ adiponectin, C1Q and collagen domain containing 1.29133
ODC1 ornithine decarboxylase 1 1.2898
F3 coagulation factor III (thromboplastin, tissue factor) 1.28919
TFF1 trefoil factor 1 1.28765
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.28734
S100A4 S100 calcium binding protein A4 1.2861
LCN2 lipocalin 2 1.2821
DCLK1 doublecortin-like kinase 1 1.28149
SP1 Sp1 transcription factor 1.28027
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.27782
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.27782
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.27689
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.27286
TF transferrin 1.27162
GRIK5 glutamate receptor, ionotropic, kainate 5 1.27132
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.27009
UBE2C ubiquitin-conjugating enzyme E2C 1.26886
MCM2 minichromosome maintenance complex component 2 1.26886
CCNE1 cyclin E1 1.26607
PPARG peroxisome proliferator-activated receptor gamma 1.26545
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.26175
GRIK2 glutamate receptor, ionotropic, kainate 2 1.25899
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.25899
COL1A2 collagen, type I, alpha 2 1.25807
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.25682
CCNA2 cyclin A2 1.25619
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.25588
AR androgen receptor 1.25588
NPTX2 neuronal pentraxin II 1.25307
FLRT2 fibronectin leucine rich transmembrane protein 2 1.25307
PRKCD protein kinase C, delta 1.25307
ALAS1 5'-aminolevulinate synthase 1 1.25245
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.25245
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.25028
CYCS cytochrome c, somatic 1.25028
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.24905
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.24905
TXNRD1 thioredoxin reductase 1 1.2475
ALAD aminolevulinate dehydratase 1.24591
PF4 platelet factor 4 1.2456
F2 coagulation factor II (thrombin) 1.24496
PCNA proliferating cell nuclear antigen 1.24338
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.23616
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.23552
EGR3 early growth response 3 1.23552
PDGFA platelet-derived growth factor alpha polypeptide 1.23488
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.23456
PRNP prion protein 1.23456
MYOF myoferlin 1.22534
CALR calreticulin 1.22177
CALCA calcitonin-related polypeptide alpha 1.22177
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.22016
EDN1 endothelin 1 1.21823
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.21759
RUNX2 runt-related transcription factor 2 1.21759
CHAT choline O-acetyltransferase 1.21663
S100A8 S100 calcium binding protein A8 1.21337
ICAM1 intercellular adhesion molecule 1 1.21304
MKI67 marker of proliferation Ki-67 1.21108
HSPA8 heat shock 70kDa protein 8 1.20816
ANXA2 annexin A2 1.20751
PSEN1 presenilin 1 1.20751
MMP1 matrix metallopeptidase 1 1.20687
ARNT aryl hydrocarbon receptor nuclear translocator 1.20526
JUNB jun B proto-oncogene 1.20394
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.20097
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.19966
PON1 paraoxonase 1 1.19933
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.19933
PLAT plasminogen activator, tissue 1.19933
DUSP6 dual specificity phosphatase 6 1.19933
BAD BCL2-associated agonist of cell death 1.19802
LEP leptin 1.19737
NPPB natriuretic peptide B 1.19737
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.19672
NTF3 neurotrophin 3 1.19542
MMP7 matrix metallopeptidase 7 1.19542
TLR4 toll-like receptor 4 1.19509
APOE apolipoprotein E 1.19509
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.19345
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.19279
NPPA natriuretic peptide A 1.18948
RRM2 ribonucleotide reductase M2 1.18948
FGF2 fibroblast growth factor 2 (basic) 1.18816
DUSP5 dual specificity phosphatase 5 1.18685
CCNB2 cyclin B2 1.18587
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.18424
IL4 interleukin 4 1.18359
LDHB lactate dehydrogenase B 1.18126
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.18026
CHEK2 checkpoint kinase 2 1.17827
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.17827
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.17596
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.17596
BAK1 BCL2-antagonist/killer 1 1.17464
DRD1 dopamine receptor D1 1.17464
CDC42 cell division cycle 42 1.17333
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.17235
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.17067
SELE selectin E 1.169
GSR glutathione reductase 1.16866
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 1.16799
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.16368
TTR transthyretin 1.16203
ENO1 enolase 1, (alpha) 1.16001
LPL lipoprotein lipase 1.16001
TAC1 tachykinin, precursor 1 1.16001
GSTA1 glutathione S-transferase alpha 1 1.15865
ERBB2 erb-b2 receptor tyrosine kinase 2 1.15831
PHB prohibitin 1.15763
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.15729
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.1556
GSTM3 glutathione S-transferase mu 3 (brain) 1.15324
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.15256
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.15122
EPAS1 endothelial PAS domain protein 1 1.14747
IHH indian hedgehog 1.14713
ACTA2 actin, alpha 2, smooth muscle, aorta 1.14713
CKB creatine kinase, brain 1.14507
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.14473
CD14 CD14 molecule 1.14438
CD44 CD44 molecule (Indian blood group) 1.14268
KLF4 Kruppel-like factor 4 (gut) 1.14234
PLSCR1 phospholipid scramblase 1 1.13929
ALDOA aldolase A, fructose-bisphosphate 1.13758
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.13279
GCLM glutamate-cysteine ligase, modifier subunit 1.13075
CXCL12 chemokine (C-X-C motif) ligand 12 1.1294
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.12838
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.12771
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.12599
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.12599
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.12599
AURKA aurora kinase A 1.12564
MAP1A microtubule-associated protein 1A 1.12426
CHRM1 cholinergic receptor, muscarinic 1 1.12357
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.12288
GFAP glial fibrillary acidic protein 1.12151
PLAU plasminogen activator, urokinase 1.12151
ATF3 activating transcription factor 3 1.12117
MAL mal, T-cell differentiation protein 1.12082
PEBP1 phosphatidylethanolamine binding protein 1 1.12082
EFNB2 ephrin-B2 1.11707
LPAR1 lysophosphatidic acid receptor 1 1.11707
PCBP1 poly(rC) binding protein 1 1.11707
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.11673
GEM GTP binding protein overexpressed in skeletal muscle 1.1136
POSTN periostin, osteoblast specific factor 1.1136
NOS1 nitric oxide synthase 1 (neuronal) 1.1136
MT1A metallothionein 1A 1.11046
CTSL cathepsin L 1.11011
SOD3 superoxide dismutase 3, extracellular 1.10803
MT2A metallothionein 2A 1.10734
ADRB2 adrenoceptor beta 2, surface 1.10734
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.10665
VIP vasoactive intestinal peptide 1.10665
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.10596
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.10353
DHFR dihydrofolate reductase 1.10353
AVP arginine vasopressin 1.10353
ALAS2 5'-aminolevulinate synthase 2 1.10317
BMP6 bone morphogenetic protein 6 1.10317
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.1014
APOD apolipoprotein D 1.09998
LOX lysyl oxidase 1.09927
WDR4 WD repeat domain 4 1.09822
RTN4 reticulon 4 1.09646
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.09646
COL6A3 collagen, type VI, alpha 3 1.09646
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.09646
SORD sorbitol dehydrogenase 1.09646
PRKCA protein kinase C, alpha 1.09541
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.09401
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.09297
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.09262
FAM20C family with sequence similarity 20, member C 1.09262
LGALS3 lectin, galactoside-binding, soluble, 3 1.09047
NGF nerve growth factor (beta polypeptide) 1.08655
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.08655
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.08161
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.08055
AQP4 aquaporin 4 1.08055
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.08019
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.0784
SYP synaptophysin 1.07732
CXCL2 chemokine (C-X-C motif) ligand 2 1.07732
RAD51 RAD51 recombinase 1.07625
PKM pyruvate kinase, muscle 1.07625
MAOB monoamine oxidase B 1.07625
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 1.07518
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 1.07518
NES nestin 1.07411
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.07411
MCM7 minichromosome maintenance complex component 7 1.07411
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.07411
APOA1 apolipoprotein A-I 1.07376
GPX2 glutathione peroxidase 2 1.07234
APAF1 apoptotic peptidase activating factor 1 1.07234
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.07234
G6PD glucose-6-phosphate dehydrogenase 1.07234
CDC20 cell division cycle 20 1.07234
LCAT lecithin-cholesterol acyltransferase 1.07128
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.07128
RHOA ras homolog family member A 1.07022
LPXN leupaxin 1.06987
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.06844
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.06844
NOVA2 neuro-oncological ventral antigen 2 1.06808
KIF23 kinesin family member 23 1.06808
PRC1 protein regulator of cytokinesis 1 1.06808
BIRC5 baculoviral IAP repeat containing 5 1.06771
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.06661
CTSK cathepsin K 1.06515
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) 1.06442
ANXA5 annexin A5 1.06442
VIM vimentin 1.0637
CLU clusterin 1.0637
RGS4 regulator of G-protein signaling 4 1.06188
FABP1 fatty acid binding protein 1, liver 1.0608
FAM107A family with sequence similarity 107, member A 1.05936
NCOA7 nuclear receptor coactivator 7 1.059
CTSS cathepsin S 1.059
TSHZ1 teashirt zinc finger homeobox 1 1.059
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.05864
MAP2K2 mitogen-activated protein kinase kinase 2 1.05864
KCNIP3 Kv channel interacting protein 3, calsenilin 1.05721
SREBF1 sterol regulatory element binding transcription factor 1 1.05573
CRH corticotropin releasing hormone 1.05498
PLP1 proteolipid protein 1 1.05461
GALM galactose mutarotase (aldose 1-epimerase) 1.05386
KIF2C kinesin family member 2C 1.05312
DES desmin 1.05312
GAL galanin/GMAP prepropeptide 1.05312
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.05089
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.05052
NTS neurotensin 1.05015
ANXA1 annexin A1 1.04904
COCH cochlin 1.04904
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.04757
ARC activity-regulated cytoskeleton-associated protein 1.04757
UHRF1 ubiquitin-like with PHD and ring finger domains 1 1.04721
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.04721
STC2 stanniocalcin 2 1.04465
SOX9 SRY (sex determining region Y)-box 9 1.04465
TUBA1A tubulin, alpha 1a 1.04163
HSPA1B heat shock 70kDa protein 1B 1.03976
OPRM1 opioid receptor, mu 1 1.03976
IGFBP4 insulin-like growth factor binding protein 4 1.03901
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.03901
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.03901
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 1.03901
CBS cystathionine-beta-synthase 1.03901
PTHLH parathyroid hormone-like hormone 1.03864
GSTM5 glutathione S-transferase mu 5 1.03864
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.03641
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.03641
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.03604
GPNMB glycoprotein (transmembrane) nmb 1.03604
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.03604
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.03456
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.03419
L1CAM L1 cell adhesion molecule 1.03419
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.03345
EZR ezrin 1.03345
RB1 retinoblastoma 1 1.03197
AREG amphiregulin 1.03084
CYC1 cytochrome c-1 1.03009
AHR aryl hydrocarbon receptor 1.02971
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.02971
EFHD1 EF-hand domain family, member D1 1.02933
NOG noggin 1.02933
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.02896
INHBE inhibin, beta E 1.02821
SIGMAR1 sigma non-opioid intracellular receptor 1 1.02821
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.02783
MMP13 matrix metallopeptidase 13 1.02708
NCAN neurocan 1.02522
OLFM1 olfactomedin 1 1.02485
XBP1 X-box binding protein 1 1.02373
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.02299
MARCKS myristoylated alanine-rich protein kinase C substrate 1.02262
PMP22 peripheral myelin protein 22 1.02262
ECH1 enoyl CoA hydratase 1, peroxisomal 1.02262
NCF2 neutrophil cytosolic factor 2 1.02262
E2F1 E2F transcription factor 1 1.02188
AKR1C2 aldo-keto reductase family 1, member C2 1.02188
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.02151
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.02077
LTF lactotransferrin 1.0204
CCPG1 cell cycle progression 1 1.0204
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.02003
KRAS Kirsten rat sarcoma viral oncogene homolog 1.01852
CTSB cathepsin B 1.01852
MGMT O-6-methylguanine-DNA methyltransferase 1.01701
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 1.01625
CA12 carbonic anhydrase XII 1.01625
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 1.01587
SP3 Sp3 transcription factor 1.01587
PTGES prostaglandin E synthase 1.01512
CST8 cystatin 8 (cystatin-related epididymal specific) 1.01361
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.01286
HBA1 hemoglobin, alpha 1 1.01212
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.01212
ATM ATM serine/threonine kinase 1.01174
STAT4 signal transducer and activator of transcription 4 1.01137
CAV1 caveolin 1, caveolae protein, 22kDa 1.01025