D-263MG Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

249 genes with high or low expression in D-263MG relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
DRG2 developmentally regulated GTP binding protein 2 3.54297
SART1 squamous cell carcinoma antigen recognized by T cells 2.93498
FLII flightless I homolog (Drosophila) 2.82211
SF3B2 splicing factor 3b, subunit 2, 145kDa 2.72814
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.66304
GRIA3 glutamate receptor, ionotropic, AMPA 3 2.59407
IL19 interleukin 19 2.45138
CD248 CD248 molecule, endosialin 2.43127
NTAN1 N-terminal asparagine amidase 2.40291
ARL2 ADP-ribosylation factor-like 2 2.37419
MSR1 macrophage scavenger receptor 1 2.27479
STEAP3 STEAP family member 3, metalloreductase 2.20788
FAM127A family with sequence similarity 127, member A 2.18324
GOLGA7 golgin A7 2.17317
COL6A2 collagen, type VI, alpha 2 2.13137
LRRC48 leucine rich repeat containing 48 2.08761
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.06858
DCN decorin 2.03527
MMP2 matrix metallopeptidase 2 2.01872
ADGRA2 adhesion G protein-coupled receptor A2 2.01716
NECAP2 NECAP endocytosis associated 2 2.01666
TOP3A topoisomerase (DNA) III alpha 2.01467
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 1.99947
SIGLEC15 sialic acid binding Ig-like lectin 15 1.99845
FOXF2 forkhead box F2 1.99115
TATDN2 TatD DNase domain containing 2 1.9885
MAGED2 melanoma antigen family D2 1.9798
GREM2 gremlin 2, DAN family BMP antagonist 1.97124
GPATCH3 G patch domain containing 3 1.94533
FAP fibroblast activation protein, alpha 1.94076
PIH1D1 PIH1 domain containing 1 1.93361
SYF2 SYF2 pre-mRNA-splicing factor 1.88786
COL16A1 collagen, type XVI, alpha 1 1.87603
TDO2 tryptophan 2,3-dioxygenase 1.86763
BANF1 barrier to autointegration factor 1 1.86641
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 1.86449
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 1.85731
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 1.8547
LALBA lactalbumin, alpha- 1.85373
GPS2 G protein pathway suppressor 2 1.84932
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 1.8314
COL1A1 collagen, type I, alpha 1 1.83127
CDC37 cell division cycle 37 1.82119
CH25H cholesterol 25-hydroxylase 1.82088
ZNF358 zinc finger protein 358 1.81733
FLNA filamin A, alpha 1.81089
NAGK N-acetylglucosamine kinase 1.80181
COL6A1 collagen, type VI, alpha 1 1.79641
GPM6A glycoprotein M6A 1.77528
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.77345
TADA3 transcriptional adaptor 3 1.77034
TMEM109 transmembrane protein 109 1.75718
SH3GL1 SH3-domain GRB2-like 1 1.75248
LRRC47 leucine rich repeat containing 47 1.73144
FBLN5 fibulin 5 1.71907
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.71864
MXRA8 matrix-remodelling associated 8 1.71503
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 1.71272
FAM168A family with sequence similarity 168, member A 1.70955
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.70719
TACC1 transforming, acidic coiled-coil containing protein 1 1.69784
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 1.68798
PLXDC1 plexin domain containing 1 1.66438
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1.65527
THBS2 thrombospondin 2 1.64877
CTSO cathepsin O 1.6422
ACTG2 actin, gamma 2, smooth muscle, enteric 1.64017
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.63826
FAM89B family with sequence similarity 89, member B 1.6376
DERL2 derlin 2 1.63641
HSPB3 heat shock 27kDa protein 3 1.63245
CCDC85B coiled-coil domain containing 85B 1.62823
EMC1 ER membrane protein complex subunit 1 1.62082
SECTM1 secreted and transmembrane 1 1.61673
CAPZB capping protein (actin filament) muscle Z-line, beta 1.61305
THADA thyroid adenoma associated 1.61166
LMOD1 leiomodin 1 (smooth muscle) 1.60609
CNIH3 cornichon family AMPA receptor auxiliary protein 3 1.60517
TMEM115 transmembrane protein 115 1.60499
SEC13 SEC13 homolog (S. cerevisiae) 1.5988
COLEC12 collectin sub-family member 12 1.59736
SYNC syncoilin, intermediate filament protein 1.58862
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 1.58622
PTPN21 protein tyrosine phosphatase, non-receptor type 21 1.57749
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.56966
CRYBA4 crystallin, beta A4 1.5662
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 1.56136
PCDHA10 protocadherin alpha 10 1.55597
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.55271
CLPTM1 cleft lip and palate associated transmembrane protein 1 1.55245
COL6A3 collagen, type VI, alpha 3 1.55085
FAM50A family with sequence similarity 50, member A 1.54895
RIN1 Ras and Rab interactor 1 1.54134
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 1.54076
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 1.53893
COL5A3 collagen, type V, alpha 3 1.5372
CTSK cathepsin K 1.5251
DPT dermatopontin 1.52107
CST8 cystatin 8 (cystatin-related epididymal specific) 1.51202
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 1.50981
RUVBL2 RuvB-like AAA ATPase 2 1.50528
OGG1 8-oxoguanine DNA glycosylase 1.50378
BACE1 beta-site APP-cleaving enzyme 1 1.49732
AMT aminomethyltransferase 1.48087
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 1.48005
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 1.47992
LTBP1 latent transforming growth factor beta binding protein 1 1.47972
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1.4793
LUM lumican 1.47436
MFAP2 microfibrillar-associated protein 2 1.47356
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 1.47152
WDR46 WD repeat domain 46 1.46958
SNED1 sushi, nidogen and EGF-like domains 1 1.46946
DEAF1 DEAF1 transcription factor 1.46674
LRRC2 leucine rich repeat containing 2 1.46501
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 1.4623
KLHL20 kelch-like family member 20 1.46165
LPPR4 lipid phosphate phosphatase-related protein type 4 1.45929
SZT2 seizure threshold 2 homolog (mouse) 1.45423
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.45138
EXTL2 exostosin-like glycosyltransferase 2 1.44861
LRRC32 leucine rich repeat containing 32 1.44559
INTS5 integrator complex subunit 5 1.44133
UBE2G2 ubiquitin-conjugating enzyme E2G 2 1.44074
MUS81 MUS81 structure-specific endonuclease subunit 1.43877
PARVA parvin, alpha 1.43778
RAB11FIP5 RAB11 family interacting protein 5 (class I) 1.43704
AK5 adenylate kinase 5 1.4308
EN1 engrailed homeobox 1 1.4279
FTSJ3 FtsJ homolog 3 (E. coli) 1.4252
NUDC nudC nuclear distribution protein 1.4247
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 1.4206
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.41727

low expression

Symbol Name Standardized Value
RBM7 RNA binding motif protein 7 -3.53725
CASP2 caspase 2, apoptosis-related cysteine peptidase -3.52132
EBP emopamil binding protein (sterol isomerase) -3.02179
IPO8 importin 8 -2.7123
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -2.67179
BPESC1 blepharophimosis, epicanthus inversus and ptosis, candidate 1 (non-protein coding) -2.61727
COX6C cytochrome c oxidase subunit VIc -2.5848
AEN apoptosis enhancing nuclease -2.53989
UBE2K ubiquitin-conjugating enzyme E2K -2.52004
NUP210 nucleoporin 210kDa -2.49207
CHD1 chromodomain helicase DNA binding protein 1 -2.46916
ERMP1 endoplasmic reticulum metallopeptidase 1 -2.31781
RAB11FIP1 RAB11 family interacting protein 1 (class I) -2.18685
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.18641
AZIN1 antizyme inhibitor 1 -2.13192
PIGA phosphatidylinositol glycan anchor biosynthesis, class A -2.11945
PDIA6 protein disulfide isomerase family A, member 6 -2.09716
MED14 mediator complex subunit 14 -2.09311
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -2.08322
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.08191
CARF calcium responsive transcription factor -2.07558
DIDO1 death inducer-obliterator 1 -2.0656
HMGB3P1 high mobility group box 3 pseudogene 1 -2.05348
METTL16 methyltransferase like 16 -2.04159
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -2.03644
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -1.97911
ZNF208 zinc finger protein 208 -1.9683
ATP11A ATPase, class VI, type 11A -1.95879
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa -1.93436
RBM12B RNA binding motif protein 12B -1.90164
PREB prolactin regulatory element binding -1.88345
ZMYM5 zinc finger, MYM-type 5 -1.87973
TMEM19 transmembrane protein 19 -1.85348
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -1.83843
GSTT1 glutathione S-transferase theta 1 -1.8165
MPZL2 myelin protein zero-like 2 -1.80726
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -1.80545
MMP15 matrix metallopeptidase 15 (membrane-inserted) -1.79868
PIAS1 protein inhibitor of activated STAT, 1 -1.79276
RFX7 regulatory factor X, 7 -1.78969
TXNL4A thioredoxin-like 4A -1.78513
PHKA2 phosphorylase kinase, alpha 2 (liver) -1.78439
DPY19L1P1 DPY19L1 pseudogene 1 -1.78269
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -1.76749
STAU2 staufen double-stranded RNA binding protein 2 -1.76727
PTBP3 polypyrimidine tract binding protein 3 -1.76673
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -1.76112
ACP1 acid phosphatase 1, soluble -1.74411
HSPA6 heat shock 70kDa protein 6 (HSP70B') -1.72603
SLBP stem-loop binding protein -1.72254
SSTR5 somatostatin receptor 5 -1.71076
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -1.70668
TTC12 tetratricopeptide repeat domain 12 -1.70367
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -1.69561
HPS6 Hermansky-Pudlak syndrome 6 -1.69455
PRPF6 pre-mRNA processing factor 6 -1.69043
E2F8 E2F transcription factor 8 -1.68211
OSBPL2 oxysterol binding protein-like 2 -1.68061
ZBTB39 zinc finger and BTB domain containing 39 -1.67114
KLF3 Kruppel-like factor 3 (basic) -1.66872
LINS lines homolog (Drosophila) -1.66417
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -1.66199
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 -1.64681
CNOT6 CCR4-NOT transcription complex, subunit 6 -1.64431
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -1.64112
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -1.64071
MED18 mediator complex subunit 18 -1.63855
CENPA centromere protein A -1.63815
ACSL6 acyl-CoA synthetase long-chain family member 6 -1.6377
FBP1 fructose-1,6-bisphosphatase 1 -1.63416
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -1.61461
CRHR2 corticotropin releasing hormone receptor 2 -1.6126
JAG2 jagged 2 -1.60265
USP3 ubiquitin specific peptidase 3 -1.59884
AADAC arylacetamide deacetylase -1.59677
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -1.59309
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -1.58685
SNX10 sorting nexin 10 -1.5867
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -1.58394
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -1.58096
ZNF652 zinc finger protein 652 -1.58018
ODC1 ornithine decarboxylase 1 -1.57677
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D -1.57597
YAF2 YY1 associated factor 2 -1.54524
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -1.53181
LYPLA1 lysophospholipase I -1.5304
HIST1H2BC histone cluster 1, H2bc -1.52952
ABLIM1 actin binding LIM protein 1 -1.52725
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -1.52012
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -1.51547
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -1.50933
F11R F11 receptor -1.5065
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -1.50589
TMOD3 tropomodulin 3 (ubiquitous) -1.5046
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 -1.50101
FUBP1 far upstream element (FUSE) binding protein 1 -1.49353
PRPH peripherin -1.49131
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -1.48739
SHMT1 serine hydroxymethyltransferase 1 (soluble) -1.485
RGS1 regulator of G-protein signaling 1 -1.48288
SAP30L SAP30-like -1.48242
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -1.47546
NPEPPS aminopeptidase puromycin sensitive -1.47396
LEFTY2 left-right determination factor 2 -1.46988
TBCA tubulin folding cofactor A -1.46183
KDM6A lysine (K)-specific demethylase 6A -1.46107
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -1.45824
KLHL3 kelch-like family member 3 -1.45659
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -1.44973
SUZ12 SUZ12 polycomb repressive complex 2 subunit -1.44744
ZNF749 zinc finger protein 749 -1.44375
SPAST spastin -1.44199
CCL21 chemokine (C-C motif) ligand 21 -1.44197
MAPK13 mitogen-activated protein kinase 13 -1.43366
RANBP6 RAN binding protein 6 -1.42169
RAD21 RAD21 homolog (S. pombe) -1.4204