Cytosolic sensors of pathogen-associated DNA Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-1834949
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Genes

66 proteins participating in the Cytosolic sensors of pathogen-associated DNA pathway from the Reactome Pathways dataset.

Symbol Name
AGER advanced glycosylation end product-specific receptor
APP amyloid beta (A4) precursor protein
CHUK conserved helix-loop-helix ubiquitous kinase
CRCP CGRP receptor component
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DTX4 deltex 4, E3 ubiquitin ligase
EP300 E1A binding protein p300
HMGB1 high mobility group box 1
IFI16 interferon, gamma-inducible protein 16
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MB21D1 Mab-21 domain containing 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLRP4 NLR family, pyrin domain containing 4
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RPS27A ribosomal protein S27a
S100A12 S100 calcium binding protein A12
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBK1 TANK-binding kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TLR3 toll-like receptor 3
TMEM173 transmembrane protein 173
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
TRIM32 tripartite motif containing 32
TRIM56 tripartite motif containing 56
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBP1 Z-DNA binding protein 1