Crohn's disease_Intestine - Large Intestine - Colon (MMHCC)_GSE6731 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6731
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Genes

600 genes differentially expressed during Crohn's disease_Intestine - Large Intestine - Colon (MMHCC)_GSE6731 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
TCOF1 Treacher Collins-Franceschetti syndrome 1 3.12097
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 3.06473
BMP1 bone morphogenetic protein 1 3.0403
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 2.97559
TSPO2 translocator protein 2 2.96929
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 2.88435
RING1 ring finger protein 1 2.74801
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.71718
BAAT bile acid CoA:amino acid N-acyltransferase 2.70883
GATA2 GATA binding protein 2 2.66366
CPNE6 copine VI (neuronal) 2.63717
ZBTB25 zinc finger and BTB domain containing 25 2.63182
LIN37 lin-37 DREAM MuvB core complex component 2.61218
STK11 serine/threonine kinase 11 2.59421
FGR FGR proto-oncogene, Src family tyrosine kinase 2.59068
KRTAP5-9 keratin associated protein 5-9 2.56191
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 2.51817
ZNF274 zinc finger protein 274 2.4953
SYNPO synaptopodin 2.47723
TBC1D22A TBC1 domain family, member 22A 2.46839
STAT5A signal transducer and activator of transcription 5A 2.46178
NIPAL3 NIPA-like domain containing 3 2.45395
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.42576
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.40719
THRA thyroid hormone receptor, alpha 2.39444
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 2.38248
MADD MAP-kinase activating death domain 2.35635
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.35533
MMP25 matrix metallopeptidase 25 2.35435
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.34484
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 2.29092
MAEA macrophage erythroblast attacher 2.28613
KIAA0141 KIAA0141 2.2777
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2 2.27155
HSF1 heat shock transcription factor 1 2.26185
ALAS1 5'-aminolevulinate synthase 1 2.26114
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.25386
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.22758
TPGS2 tubulin polyglutamylase complex subunit 2 2.21726
M6PR mannose-6-phosphate receptor (cation dependent) 2.20642
FABP7 fatty acid binding protein 7, brain 2.18103
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.17854
ELF4 E74-like factor 4 (ets domain transcription factor) 2.16908
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 2.16447
DHPS deoxyhypusine synthase 2.1597
INHBC inhibin, beta C 2.15842
MSH3 mutS homolog 3 2.15154
MFSD5 major facilitator superfamily domain containing 5 2.14687
PSKH1 protein serine kinase H1 2.14667
FGL1 fibrinogen-like 1 2.13489
BCR breakpoint cluster region 2.12657
PRKD2 protein kinase D2 2.12224
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 2.11822
OMG oligodendrocyte myelin glycoprotein 2.09821
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.09489
GAS1 growth arrest-specific 1 2.09457
RPS20 ribosomal protein S20 2.08189
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.07941
AMBP alpha-1-microglobulin/bikunin precursor 2.07849
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2.07634
UBE2L3 ubiquitin-conjugating enzyme E2L 3 2.0747
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.06887
OPRK1 opioid receptor, kappa 1 2.06093
ERV9-1 endogenous retrovirus group 9, member 1 2.05721
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 2.04863
GAA glucosidase, alpha; acid 2.04335
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.02906
ZNF710 zinc finger protein 710 2.02704
SRRT serrate, RNA effector molecule 2.02481
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 2.01684
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 2.01184
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 2.00788
EPO erythropoietin 2.0069
ATP7B ATPase, Cu++ transporting, beta polypeptide 1.97864
SDS serine dehydratase 1.97527
KRT9 keratin 9, type I 1.97101
KLHL25 kelch-like family member 25 1.96427
C5ORF45 chromosome 5 open reading frame 45 1.96188
TPMT thiopurine S-methyltransferase 1.94783
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.94219
RPP38 ribonuclease P/MRP 38kDa subunit 1.93649
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 1.93251
UNC5B unc-5 homolog B (C. elegans) 1.93188
FAM131A family with sequence similarity 131, member A 1.92666
CDR2L cerebellar degeneration-related protein 2-like 1.92254
ASIC3 acid sensing (proton gated) ion channel 3 1.91532
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.90934
FLT3LG fms-related tyrosine kinase 3 ligand 1.90213
RABL3 RAB, member of RAS oncogene family-like 3 1.89733
ASPHD1 aspartate beta-hydroxylase domain containing 1 1.89532
ZFPL1 zinc finger protein-like 1 1.89414
CHGB chromogranin B 1.88487
DUSP9 dual specificity phosphatase 9 1.88272
NRGN neurogranin (protein kinase C substrate, RC3) 1.87863
DDIT3 DNA-damage-inducible transcript 3 1.86735
ADA adenosine deaminase 1.86303
AATK apoptosis-associated tyrosine kinase 1.86073
CTRL chymotrypsin-like 1.8554
RAB11FIP5 RAB11 family interacting protein 5 (class I) 1.85489
FASLG Fas ligand (TNF superfamily, member 6) 1.85263
SLC38A3 solute carrier family 38, member 3 1.85191
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 1.85187
DOLK dolichol kinase 1.85153
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 1.85024
NUP210 nucleoporin 210kDa 1.84057
SIX6 SIX homeobox 6 1.82986
TPT1 tumor protein, translationally-controlled 1 1.82324
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 1.82288
GPR161 G protein-coupled receptor 161 1.8125
RWDD2A RWD domain containing 2A 1.8114
GSTM3 glutathione S-transferase mu 3 (brain) 1.80467
TNNC1 troponin C type 1 (slow) 1.79718
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 1.79007
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 1.7883
WAS Wiskott-Aldrich syndrome 1.78785
TTLL4 tubulin tyrosine ligase-like family member 4 1.78595
TCTA T-cell leukemia translocation altered 1.77976
CSPG4 chondroitin sulfate proteoglycan 4 1.77321
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 1.77183
SZT2 seizure threshold 2 homolog (mouse) 1.76859
ADCY1 adenylate cyclase 1 (brain) 1.76173
TNPO3 transportin 3 1.76088
TMOD1 tropomodulin 1 1.76039
ADORA2A adenosine A2a receptor 1.75768
MANBA mannosidase, beta A, lysosomal 1.75615
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.75538
GLYAT glycine-N-acyltransferase 1.75424
ZBTB43 zinc finger and BTB domain containing 43 1.75395
CDK5 cyclin-dependent kinase 5 1.75191
AP3M2 adaptor-related protein complex 3, mu 2 subunit 1.74593
FIG4 FIG4 phosphoinositide 5-phosphatase 1.73284
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 1.73273
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 1.72728
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 1.72349
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.7232
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 1.72133
RPS25 ribosomal protein S25 1.71784
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 1.7174
CNTN2 contactin 2 (axonal) 1.71694
FOSL2 FOS-like antigen 2 1.71651
PCYT1B phosphate cytidylyltransferase 1, choline, beta 1.71586
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 1.71145
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.71073
IGF1R insulin-like growth factor 1 receptor 1.7096
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 1.70885
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.70699
CAMK1G calcium/calmodulin-dependent protein kinase IG 1.70539
SRPX sushi-repeat containing protein, X-linked 1.70467
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.698
ZNRF4 zinc and ring finger 4 1.69602
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 1.69586
RARB retinoic acid receptor, beta 1.69396
NAGA N-acetylgalactosaminidase, alpha- 1.69317
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) 1.69102
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 1.6908
IGF2R insulin-like growth factor 2 receptor 1.69044
RBP3 retinol binding protein 3, interstitial 1.68654
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.6792
HNRNPF heterogeneous nuclear ribonucleoprotein F 1.67851
KHNYN KH and NYN domain containing 1.67736
NLE1 notchless homolog 1 (Drosophila) 1.66947
MORC2 MORC family CW-type zinc finger 2 1.66728
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 1.66501
PPAP2C phosphatidic acid phosphatase type 2C 1.66254
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.6615
CCNF cyclin F 1.6606
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 1.65967
SQSTM1 sequestosome 1 1.65892
PCDH9 protocadherin 9 1.65186
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 1.65108
INSL3 insulin-like 3 (Leydig cell) 1.65076
EHD1 EH-domain containing 1 1.64915
NLGN4Y neuroligin 4, Y-linked 1.64836
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 1.64725
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 1.64436
MPO myeloperoxidase 1.64158
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 1.64038
EIF3J eukaryotic translation initiation factor 3, subunit J 1.6381
PDCD1 programmed cell death 1 1.63747
OIP5 Opa interacting protein 5 1.63719
KIAA0930 KIAA0930 1.63421
APOC1 apolipoprotein C-I 1.63317
PLG plasminogen 1.63174
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.62912
RGS9 regulator of G-protein signaling 9 1.62875
IFRD2 interferon-related developmental regulator 2 1.62483
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.62423
AANAT aralkylamine N-acetyltransferase 1.62156
CUX1 cut-like homeobox 1 1.62146
PGAP2 post-GPI attachment to proteins 2 1.61868
ZNF185 zinc finger protein 185 (LIM domain) 1.6177
PPIF peptidylprolyl isomerase F 1.61173
HDAC3 histone deacetylase 3 1.60652
ADPRH ADP-ribosylarginine hydrolase 1.60278
GP1BA glycoprotein Ib (platelet), alpha polypeptide 1.59883
GNRH2 gonadotropin-releasing hormone 2 1.59834
CDC25A cell division cycle 25A 1.58739
RANGAP1 Ran GTPase activating protein 1 1.57916
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.57747
NUP62 nucleoporin 62kDa 1.57409
STAT4 signal transducer and activator of transcription 4 1.57196
ONECUT2 one cut homeobox 2 1.56538
S100A1 S100 calcium binding protein A1 1.56365
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 1.56003
C1ORF68 chromosome 1 open reading frame 68 1.55974
INSM1 insulinoma-associated 1 1.55731
ARHGAP1 Rho GTPase activating protein 1 1.55435
DTNA dystrobrevin, alpha 1.54898
PDE10A phosphodiesterase 10A 1.5486
HFE hemochromatosis 1.54856
CFHR3 complement factor H-related 3 1.54769
PRPF19 pre-mRNA processing factor 19 1.54378
GK2 glycerol kinase 2 1.5436
CD6 CD6 molecule 1.54301
SCN5A sodium channel, voltage gated, type V alpha subunit 1.5429
HSPA6 heat shock 70kDa protein 6 (HSP70B') 1.54052
TTLL3 tubulin tyrosine ligase-like family member 3 1.53893
KPNA6 karyopherin alpha 6 (importin alpha 7) 1.53828
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 1.53799
JPH3 junctophilin 3 1.53699
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.53326
ADRB1 adrenoceptor beta 1 1.53281
ALX1 ALX homeobox 1 1.53112
HIST1H3I histone cluster 1, H3i 1.52953
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.5287
PRIM1 primase, DNA, polypeptide 1 (49kDa) 1.52573
HMGA2 high mobility group AT-hook 2 1.52091
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.51373
ZNF646 zinc finger protein 646 1.51164
GREM1 gremlin 1, DAN family BMP antagonist 1.50556
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 1.50374
S100A2 S100 calcium binding protein A2 1.50307
GCAT glycine C-acetyltransferase 1.50193
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.50123
TBKBP1 TBK1 binding protein 1 1.50058
CYHR1 cysteine/histidine-rich 1 1.4997
ILK integrin-linked kinase 1.49882
FCN1 ficolin (collagen/fibrinogen domain containing) 1 1.498
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 1.49786
PHLDA1 pleckstrin homology-like domain, family A, member 1 1.49581
SHH sonic hedgehog 1.49548
NTSR2 neurotensin receptor 2 1.49064
INTS9 integrator complex subunit 9 1.48727
LDB3 LIM domain binding 3 1.48497
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 1.47716
PISD phosphatidylserine decarboxylase 1.47619
KRT76 keratin 76, type II 1.47442
CELF3 CUGBP, Elav-like family member 3 1.47402
IQSEC1 IQ motif and Sec7 domain 1 1.4735
SYT2 synaptotagmin II 1.47248
STK17A serine/threonine kinase 17a 1.47144
SNX17 sorting nexin 17 1.46842
ZNF674 zinc finger protein 674 1.46456
MBD1 methyl-CpG binding domain protein 1 1.46218
ICOSLG inducible T-cell co-stimulator ligand 1.4618
SLC10A3 solute carrier family 10, member 3 1.45828
MCC mutated in colorectal cancers 1.45709
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.45645
FOXN1 forkhead box N1 1.45611
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.45226
RPS27 ribosomal protein S27 1.45075
ZMYM3 zinc finger, MYM-type 3 1.44925
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 1.44674
ASMT acetylserotonin O-methyltransferase 1.44524
SMG7-AS1 SMG7 antisense RNA 1 1.44469
RBM15B RNA binding motif protein 15B 1.44086
FLT1 fms-related tyrosine kinase 1 1.44026
PNMT phenylethanolamine N-methyltransferase 1.43995
ODF1 outer dense fiber of sperm tails 1 1.43782
KYNU kynureninase 1.4373
PEX14 peroxisomal biogenesis factor 14 1.43672
ARID1A AT rich interactive domain 1A (SWI-like) 1.43669
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 1.43217
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 1.4317
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.42932
CDK12 cyclin-dependent kinase 12 1.42854
SFTPC surfactant protein C 1.42607
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 1.42361
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 1.42225
MAML3 mastermind-like 3 (Drosophila) 1.42074
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.41915
GNLY granulysin 1.41914
TAGLN3 transgelin 3 1.41869
CYTH1 cytohesin 1 1.41794
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.4177
APLP1 amyloid beta (A4) precursor-like protein 1 1.41731
APLNR apelin receptor 1.41526
LOC1720 dihydrofolate reductase pseudogene 1.41357
ZNF330 zinc finger protein 330 1.41236
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 1.41122
NBPF10 neuroblastoma breakpoint family, member 10 1.41075
GPR3 G protein-coupled receptor 3 1.40985
BCL2 B-cell CLL/lymphoma 2 1.40916
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 1.4068
OVOL3 ovo-like zinc finger 3 1.40326
TPD52L2 tumor protein D52-like 2 1.402
CRH corticotropin releasing hormone 1.4019
SPN sialophorin 1.39936
FBP2 fructose-1,6-bisphosphatase 2 1.39638
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 1.39546

decreased expression

Symbol Name Standardized Value
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -3.22352
RAB5B RAB5B, member RAS oncogene family -2.89859
BRAP BRCA1 associated protein -2.82759
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -2.8213
ERP44 endoplasmic reticulum protein 44 -2.79566
MAPK14 mitogen-activated protein kinase 14 -2.77146
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 -2.66109
AP2B1 adaptor-related protein complex 2, beta 1 subunit -2.6588
GSK3B glycogen synthase kinase 3 beta -2.64278
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 -2.63668
EML2 echinoderm microtubule associated protein like 2 -2.62698
MPHOSPH9 M-phase phosphoprotein 9 -2.60434
SF1 splicing factor 1 -2.54021
KPNA3 karyopherin alpha 3 (importin alpha 4) -2.4963
KRT85 keratin 85, type II -2.48976
WDR73 WD repeat domain 73 -2.46501
ZFR zinc finger RNA binding protein -2.45926
ZNF124 zinc finger protein 124 -2.45621
HRH1 histamine receptor H1 -2.44359
RHOA ras homolog family member A -2.40993
STX10 syntaxin 10 -2.40955
LPAR2 lysophosphatidic acid receptor 2 -2.3633
PHIP pleckstrin homology domain interacting protein -2.34985
OGG1 8-oxoguanine DNA glycosylase -2.34704
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.33498
RAB11B RAB11B, member RAS oncogene family -2.32821
CDK6 cyclin-dependent kinase 6 -2.32745
HIST1H2AL histone cluster 1, H2al -2.31999
PTGDR2 prostaglandin D2 receptor 2 -2.2842
PICK1 protein interacting with PRKCA 1 -2.2794
SPRR2D small proline-rich protein 2D -2.27707
MPDU1 mannose-P-dolichol utilization defect 1 -2.26485
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -2.25753
HSPA4 heat shock 70kDa protein 4 -2.25528
ATAD2B ATPase family, AAA domain containing 2B -2.24787
COL4A6 collagen, type IV, alpha 6 -2.24154
MAX MYC associated factor X -2.2271
ZMYND8 zinc finger, MYND-type containing 8 -2.21729
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -2.21029
TBC1D5 TBC1 domain family, member 5 -2.2054
ZBTB22 zinc finger and BTB domain containing 22 -2.19729
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 -2.18803
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -2.17734
SLIT2 slit homolog 2 (Drosophila) -2.17134
PRRC1 proline-rich coiled-coil 1 -2.16671
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -2.16381
ACD adrenocortical dysplasia homolog (mouse) -2.1611
NKTR natural killer cell triggering receptor -2.15789
IGF1 insulin-like growth factor 1 (somatomedin C) -2.15016
MAP2K5 mitogen-activated protein kinase kinase 5 -2.14126
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -2.1327
SPRR2C small proline-rich protein 2C (pseudogene) -2.12108
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase -2.1053
ATXN7L3B ataxin 7-like 3B -2.09812
TRAIP TRAF interacting protein -2.0919
BIK BCL2-interacting killer (apoptosis-inducing) -2.07898
NRF1 nuclear respiratory factor 1 -2.07751
ALPP alkaline phosphatase, placental -2.07672
ULK2 unc-51 like autophagy activating kinase 2 -2.07421
EDDM3A epididymal protein 3A -2.06591
TCF20 transcription factor 20 (AR1) -2.06441
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) -2.06076
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -2.0584
ZNF391 zinc finger protein 391 -2.05491
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -2.05213
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) -2.04481
DHRS1 dehydrogenase/reductase (SDR family) member 1 -2.0366
KDM4B lysine (K)-specific demethylase 4B -2.03592
CRTC1 CREB regulated transcription coactivator 1 -2.03285
GRM4 glutamate receptor, metabotropic 4 -2.0256
PTOV1-AS1 PTOV1 antisense RNA 1 -2.02071
PFDN6 prefoldin subunit 6 -2.01901
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.01543
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 -2.00912
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -2.00726
FAM178A family with sequence similarity 178, member A -2.00593
IZUMO4 IZUMO family member 4 -2.00033
SCN4A sodium channel, voltage gated, type IV alpha subunit -1.99985
SCTR secretin receptor -1.99917
HAVCR1 hepatitis A virus cellular receptor 1 -1.99852
FAM172A family with sequence similarity 172, member A -1.99848
GATA3 GATA binding protein 3 -1.9917
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -1.98207
CCDC88C coiled-coil domain containing 88C -1.98126
LINC00599 long intergenic non-protein coding RNA 599 -1.97847
WRN Werner syndrome, RecQ helicase-like -1.97551
CCNT1 cyclin T1 -1.97392
DMWD dystrophia myotonica, WD repeat containing -1.96303
NPTN neuroplastin -1.95961
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) -1.95732
FAM107A family with sequence similarity 107, member A -1.95144
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -1.946
ACIN1 apoptotic chromatin condensation inducer 1 -1.94262
SSPN sarcospan -1.94161
TRIP13 thyroid hormone receptor interactor 13 -1.94011
NSFL1C NSFL1 (p97) cofactor (p47) -1.93827
TRIM66 tripartite motif containing 66 -1.93811
SYT17 synaptotagmin XVII -1.93786
LPAR1 lysophosphatidic acid receptor 1 -1.93624
TARBP2 TAR (HIV-1) RNA binding protein 2 -1.91249
SETDB1 SET domain, bifurcated 1 -1.90949
ARF6 ADP-ribosylation factor 6 -1.90873
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -1.90368
CAMK2B calcium/calmodulin-dependent protein kinase II beta -1.90174
NFYC nuclear transcription factor Y, gamma -1.9005
CCIN calicin -1.89928
AHNAK AHNAK nucleoprotein -1.89661
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -1.89595
FKBP1A FK506 binding protein 1A, 12kDa -1.89365
MARK2 MAP/microtubule affinity-regulating kinase 2 -1.89011
TMX4 thioredoxin-related transmembrane protein 4 -1.88943
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -1.88323
C9ORF91 chromosome 9 open reading frame 91 -1.88126
IGSF3 immunoglobulin superfamily, member 3 -1.88122
CPA1 carboxypeptidase A1 (pancreatic) -1.87986
HCG26 HLA complex group 26 (non-protein coding) -1.86864
SPATA2L spermatogenesis associated 2-like -1.86748
CROCC ciliary rootlet coiled-coil, rootletin -1.86324
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma -1.86215
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa -1.85976
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -1.85871
IL4 interleukin 4 -1.856
BAZ1B bromodomain adjacent to zinc finger domain, 1B -1.8508
NEUROD2 neuronal differentiation 2 -1.8461
SNX13 sorting nexin 13 -1.84463
STARD5 StAR-related lipid transfer (START) domain containing 5 -1.84431
DRD5 dopamine receptor D5 -1.83981
JRK Jrk homolog (mouse) -1.83891
ZNF711 zinc finger protein 711 -1.83601
SYT5 synaptotagmin V -1.83101
KIAA0430 KIAA0430 -1.82836
RUNX1 runt-related transcription factor 1 -1.82389
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -1.82058
FOLR1 folate receptor 1 (adult) -1.82056
PTMA prothymosin, alpha -1.81043
RABGGTA Rab geranylgeranyltransferase, alpha subunit -1.81007
ARAF A-Raf proto-oncogene, serine/threonine kinase -1.80976
CBY1 chibby homolog 1 (Drosophila) -1.80964
HCG9 HLA complex group 9 (non-protein coding) -1.80583
NCAPH non-SMC condensin I complex, subunit H -1.79408
MAPK1 mitogen-activated protein kinase 1 -1.79237
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) -1.79143
MSL1 male-specific lethal 1 homolog (Drosophila) -1.78523
KIFC1 kinesin family member C1 -1.78488
NUTF2 nuclear transport factor 2 -1.77882
FADS1 fatty acid desaturase 1 -1.7752
GUSB glucuronidase, beta -1.7745
SFPQ splicing factor proline/glutamine-rich -1.77308
CDC40 cell division cycle 40 -1.7691
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -1.76874
VASH1 vasohibin 1 -1.76699
ART1 ADP-ribosyltransferase 1 -1.76477
GAS8-AS1 GAS8 antisense RNA 1 -1.76435
EXT1 exostosin glycosyltransferase 1 -1.76002
GBX1 gastrulation brain homeobox 1 -1.75593
EFNB1 ephrin-B1 -1.75197
PRPH2 peripherin 2 (retinal degeneration, slow) -1.74441
OSTF1 osteoclast stimulating factor 1 -1.74423
COL6A1 collagen, type VI, alpha 1 -1.74304
RPS10 ribosomal protein S10 -1.74225
DHH desert hedgehog -1.73816
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -1.73758
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -1.73734
NUAK1 NUAK family, SNF1-like kinase, 1 -1.73721
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.73694
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -1.73492
SMAP1 small ArfGAP 1 -1.73204
BLMH bleomycin hydrolase -1.73167
RAE1 ribonucleic acid export 1 -1.72759
ZNF230 zinc finger protein 230 -1.7256
TF transferrin -1.72558
GLI1 GLI family zinc finger 1 -1.72422
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 -1.72328
TBC1D2B TBC1 domain family, member 2B -1.72149
SIM1 single-minded family bHLH transcription factor 1 -1.72007
EXOG endo/exonuclease (5'-3'), endonuclease G-like -1.71522
MOG myelin oligodendrocyte glycoprotein -1.71481
PPT2 palmitoyl-protein thioesterase 2 -1.714
CTIF CBP80/20-dependent translation initiation factor -1.71259
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -1.71212
ARL2BP ADP-ribosylation factor-like 2 binding protein -1.71184
PLCD1 phospholipase C, delta 1 -1.70413
CLCN4 chloride channel, voltage-sensitive 4 -1.70389
ZNF500 zinc finger protein 500 -1.70217
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -1.69641
C9ORF114 chromosome 9 open reading frame 114 -1.69254
PON3 paraoxonase 3 -1.69236
DGCR6L DiGeorge syndrome critical region gene 6-like -1.68866
EDC4 enhancer of mRNA decapping 4 -1.68668
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -1.68227
ACACA acetyl-CoA carboxylase alpha -1.67745
CTNND1 catenin (cadherin-associated protein), delta 1 -1.67674
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -1.67565
DISC1 disrupted in schizophrenia 1 -1.67404
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -1.67355
GUCA1B guanylate cyclase activator 1B (retina) -1.67132
AGER advanced glycosylation end product-specific receptor -1.67046
COPS6 COP9 signalosome subunit 6 -1.66782
MAU2 MAU2 sister chromatid cohesion factor -1.66313
SIPA1L3 signal-induced proliferation-associated 1 like 3 -1.66246
CCDC6 coiled-coil domain containing 6 -1.66203
ERC2 ELKS/RAB6-interacting/CAST family member 2 -1.65742
PABPN1 poly(A) binding protein, nuclear 1 -1.65515
KEL Kell blood group, metallo-endopeptidase -1.65412
PIAS2 protein inhibitor of activated STAT, 2 -1.64493
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain -1.6426
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -1.64178
BAZ2A bromodomain adjacent to zinc finger domain, 2A -1.63879
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -1.63023
SEPHS1 selenophosphate synthetase 1 -1.62948
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -1.62814
TK2 thymidine kinase 2, mitochondrial -1.62744
TCL1B T-cell leukemia/lymphoma 1B -1.62707
AMPD2 adenosine monophosphate deaminase 2 -1.62605
MYOM1 myomesin 1 -1.62528
AKAP8 A kinase (PRKA) anchor protein 8 -1.62136
EDNRA endothelin receptor type A -1.62128
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -1.62084
IDS iduronate 2-sulfatase -1.61735
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) -1.61216
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha -1.60932
DGUOK deoxyguanosine kinase -1.60756
SH3PXD2A SH3 and PX domains 2A -1.60622
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) -1.6051
PCNXL2 pecanex-like 2 (Drosophila) -1.60509
TMSB4X thymosin beta 4, X-linked -1.60283
AP4M1 adaptor-related protein complex 4, mu 1 subunit -1.60126
RAP2A RAP2A, member of RAS oncogene family -1.59438
FOSL1 FOS-like antigen 1 -1.59216
HDAC6 histone deacetylase 6 -1.58971
PKD2 polycystic kidney disease 2 (autosomal dominant) -1.58776
CST2 cystatin SA -1.58701
GPR50 G protein-coupled receptor 50 -1.58453
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -1.58214
MDC1 mediator of DNA-damage checkpoint 1 -1.58151
DLEC1 deleted in lung and esophageal cancer 1 -1.58019
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -1.57983
TRIM9 tripartite motif containing 9 -1.57768
MUTYH mutY homolog -1.57721
COX20 COX20 cytochrome c oxidase assembly factor -1.5764
C17ORF75 chromosome 17 open reading frame 75 -1.57639
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -1.57457
SIGLEC7 sialic acid binding Ig-like lectin 7 -1.57413
CLCN6 chloride channel, voltage-sensitive 6 -1.5734
BRPF1 bromodomain and PHD finger containing, 1 -1.57064
PARK2 parkin RBR E3 ubiquitin protein ligase -1.56932
DDAH2 dimethylarginine dimethylaminohydrolase 2 -1.56207
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -1.55929
SNX19 sorting nexin 19 -1.55761
CDK16 cyclin-dependent kinase 16 -1.55423
GLUD2 glutamate dehydrogenase 2 -1.5536
HCG4B HLA complex group 4B (non-protein coding) -1.55339
PART1 prostate androgen-regulated transcript 1 (non-protein coding) -1.55072
ADORA3 adenosine A3 receptor -1.55052
FOLR2 folate receptor 2 (fetal) -1.54878
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -1.54795
KLF5 Kruppel-like factor 5 (intestinal) -1.54597
PRKD3 protein kinase D3 -1.54478
ZNF200 zinc finger protein 200 -1.54398
CLSTN3 calsyntenin 3 -1.54352
NFYA nuclear transcription factor Y, alpha -1.54275
FBLN1 fibulin 1 -1.54255
DDB2 damage-specific DNA binding protein 2, 48kDa -1.54228
LMNB1 lamin B1 -1.53714
SRR serine racemase -1.53698
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -1.5354
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 -1.53489
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -1.53488
MXRA8 matrix-remodelling associated 8 -1.5303
ITSN2 intersectin 2 -1.52801
TRIM23 tripartite motif containing 23 -1.52678
AGGF1 angiogenic factor with G patch and FHA domains 1 -1.52509
TEC tec protein tyrosine kinase -1.52372
SGSM3 small G protein signaling modulator 3 -1.52084
CD72 CD72 molecule -1.51683
DLX2 distal-less homeobox 2 -1.51612
DNASE1L1 deoxyribonuclease I-like 1 -1.51369
ARID4A AT rich interactive domain 4A (RBP1-like) -1.51289
CCDC64 coiled-coil domain containing 64 -1.51111
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -1.51069
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -1.50695
LCAT lecithin-cholesterol acyltransferase -1.5003
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -1.49724
CANX calnexin -1.4916
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -1.48793
TRIO trio Rho guanine nucleotide exchange factor -1.48643
BTG1 B-cell translocation gene 1, anti-proliferative -1.48474
RAB27A RAB27A, member RAS oncogene family -1.4843
SGPL1 sphingosine-1-phosphate lyase 1 -1.48217
CASP9 caspase 9, apoptosis-related cysteine peptidase -1.48043
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -1.4798
CNR2 cannabinoid receptor 2 (macrophage) -1.47582
AOC2 amine oxidase, copper containing 2 (retina-specific) -1.47567
RUFY3 RUN and FYVE domain containing 3 -1.47453
PLCH1 phospholipase C, eta 1 -1.47329
ZBTB7A zinc finger and BTB domain containing 7A -1.47305
MYB v-myb avian myeloblastosis viral oncogene homolog -1.47246
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 -1.46853
DCT dopachrome tautomerase -1.46847
KLF1 Kruppel-like factor 1 (erythroid) -1.46764