Common Variable Immunodeficiency Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A hypogammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells. Patients with common variable immunodeficiency have marked reduction in serum levels of both immunoglobulin G (IgG) and immunoglobulin A (IgA); about half of these patients also have reduced immunoglobulin M (IgM). (Human Disease Ontology, DOID_12177)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D017074
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Genes

6 genes/proteins associated with the disease Common Variable Immunodeficiency from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 2.88009
CD81 CD81 molecule 2.88009
ICOS inducible T-cell co-stimulator 2.88009
CD19 CD19 molecule 2.88009
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.88009
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 2.88009