Collagen formation Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). (Gene Ontology, GO_0032964)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-1474290
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Genes

86 proteins participating in the Collagen formation pathway from the Reactome Pathways dataset.

Symbol Name
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
BMP1 bone morphogenetic protein 1
CD151 CD151 molecule (Raph blood group)
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL11A2 collagen, type XI, alpha 2
COL12A1 collagen, type XII, alpha 1
COL13A1 collagen, type XIII, alpha 1
COL14A1 collagen, type XIV, alpha 1
COL15A1 collagen, type XV, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL17A1 collagen, type XVII, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL20A1 collagen, type XX, alpha 1
COL21A1 collagen, type XXI, alpha 1
COL22A1 collagen, type XXII, alpha 1
COL23A1 collagen, type XXIII, alpha 1
COL24A1 collagen, type XXIV, alpha 1
COL25A1 collagen, type XXV, alpha 1
COL26A1 collagen, type XXVI, alpha 1
COL27A1 collagen, type XXVII, alpha 1
COL28A1 collagen, type XXVIII, alpha 1
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COL5A3 collagen, type V, alpha 3
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
COL6A5 collagen, type VI, alpha 5
COL6A6 collagen, type VI, alpha 6
COL7A1 collagen, type VII, alpha 1
COL8A1 collagen, type VIII, alpha 1
COL8A2 collagen, type VIII, alpha 2
COL9A1 collagen, type IX, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRTAP cartilage associated protein
CTSB cathepsin B
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
DST dystonin
ITGA6 integrin, alpha 6
ITGB4 integrin, beta 4
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LOX lysyl oxidase
LOXL1 lysyl oxidase-like 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LOXL4 lysyl oxidase-like 4
MMP13 matrix metallopeptidase 13
MMP20 matrix metallopeptidase 20
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
P3H1 prolyl 3-hydroxylase 1
P3H2 prolyl 3-hydroxylase 2
P3H3 prolyl 3-hydroxylase 3
P4HB prolyl 4-hydroxylase, beta polypeptide
PCOLCE procollagen C-endopeptidase enhancer
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLEC plectin
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PPIB peptidylprolyl isomerase B (cyclophilin B)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
TLL1 tolloid-like 1
TLL2 tolloid-like 2