Dataset | Reactome Pathways |

Category | structural or functional annotations |

Type | pathway |

Description | The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). (Gene Ontology, GO_0032964) |

External Link | http://www.reactome.org/PathwayBrowser/#/R-HSA-1474290 |

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86 proteins participating in the **Collagen formation** pathway from the Reactome Pathways dataset.

Symbol | Name |
---|---|

ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 |

ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |

ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |

BMP1 | bone morphogenetic protein 1 |

CD151 | CD151 molecule (Raph blood group) |

COL10A1 | collagen, type X, alpha 1 |

COL11A1 | collagen, type XI, alpha 1 |

COL11A2 | collagen, type XI, alpha 2 |

COL12A1 | collagen, type XII, alpha 1 |

COL13A1 | collagen, type XIII, alpha 1 |

COL14A1 | collagen, type XIV, alpha 1 |

COL15A1 | collagen, type XV, alpha 1 |

COL16A1 | collagen, type XVI, alpha 1 |

COL17A1 | collagen, type XVII, alpha 1 |

COL18A1 | collagen, type XVIII, alpha 1 |

COL19A1 | collagen, type XIX, alpha 1 |

COL1A1 | collagen, type I, alpha 1 |

COL1A2 | collagen, type I, alpha 2 |

COL20A1 | collagen, type XX, alpha 1 |

COL21A1 | collagen, type XXI, alpha 1 |

COL22A1 | collagen, type XXII, alpha 1 |

COL23A1 | collagen, type XXIII, alpha 1 |

COL24A1 | collagen, type XXIV, alpha 1 |

COL25A1 | collagen, type XXV, alpha 1 |

COL26A1 | collagen, type XXVI, alpha 1 |

COL27A1 | collagen, type XXVII, alpha 1 |

COL28A1 | collagen, type XXVIII, alpha 1 |

COL2A1 | collagen, type II, alpha 1 |

COL3A1 | collagen, type III, alpha 1 |

COL4A1 | collagen, type IV, alpha 1 |

COL4A2 | collagen, type IV, alpha 2 |

COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |

COL4A4 | collagen, type IV, alpha 4 |

COL4A5 | collagen, type IV, alpha 5 |

COL4A6 | collagen, type IV, alpha 6 |

COL5A1 | collagen, type V, alpha 1 |

COL5A2 | collagen, type V, alpha 2 |

COL5A3 | collagen, type V, alpha 3 |

COL6A1 | collagen, type VI, alpha 1 |

COL6A2 | collagen, type VI, alpha 2 |

COL6A3 | collagen, type VI, alpha 3 |

COL6A5 | collagen, type VI, alpha 5 |

COL6A6 | collagen, type VI, alpha 6 |

COL7A1 | collagen, type VII, alpha 1 |

COL8A1 | collagen, type VIII, alpha 1 |

COL8A2 | collagen, type VIII, alpha 2 |

COL9A1 | collagen, type IX, alpha 1 |

COL9A2 | collagen, type IX, alpha 2 |

COL9A3 | collagen, type IX, alpha 3 |

COLGALT1 | collagen beta(1-O)galactosyltransferase 1 |

COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |

CRTAP | cartilage associated protein |

CTSB | cathepsin B |

CTSL | cathepsin L |

CTSS | cathepsin S |

CTSV | cathepsin V |

DST | dystonin |

ITGA6 | integrin, alpha 6 |

ITGB4 | integrin, beta 4 |

LAMA3 | laminin, alpha 3 |

LAMB3 | laminin, beta 3 |

LAMC2 | laminin, gamma 2 |

LOX | lysyl oxidase |

LOXL1 | lysyl oxidase-like 1 |

LOXL2 | lysyl oxidase-like 2 |

LOXL3 | lysyl oxidase-like 3 |

LOXL4 | lysyl oxidase-like 4 |

MMP13 | matrix metallopeptidase 13 |

MMP20 | matrix metallopeptidase 20 |

MMP3 | matrix metallopeptidase 3 |

MMP7 | matrix metallopeptidase 7 |

MMP9 | matrix metallopeptidase 9 |

P3H1 | prolyl 3-hydroxylase 1 |

P3H2 | prolyl 3-hydroxylase 2 |

P3H3 | prolyl 3-hydroxylase 3 |

P4HB | prolyl 4-hydroxylase, beta polypeptide |

PCOLCE | procollagen C-endopeptidase enhancer |

PCOLCE2 | procollagen C-endopeptidase enhancer 2 |

PLEC | plectin |

PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |

PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |

PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 |

PPIB | peptidylprolyl isomerase B (cyclophilin B) |

SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |

TLL1 | tolloid-like 1 |

TLL2 | tolloid-like 2 |