Cholesterol biosynthesis Gene Set

Dataset PANTHER Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. (Gene Ontology, GO_0006695)
External Link http://www.pantherdb.org/pathway/pathDetail.do?clsAccession=P00014
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Genes

11 proteins participating in the Cholesterol biosynthesis pathway from the PANTHER Pathways dataset.

Symbol Name
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
GGPS1 geranylgeranyl diphosphate synthase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI2 isopentenyl-diphosphate delta isomerase 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
PMVK phosphomevalonate kinase
SQLE squalene epoxidase