Cerebellar Ataxia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A cerebellar disease characterized by ataxia originating in the cerebellum. (Human Disease Ontology, DOID_0050753)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D002524
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Genes

71 genes/proteins associated with the disease Cerebellar Ataxia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SCN8A sodium channel, voltage gated, type VIII alpha subunit 2.88009
RPL27A ribosomal protein L27a 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.83735
BAX BCL2-associated X protein 1.77531
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.69211
TNF tumor necrosis factor 1.58042
VEGFA vascular endothelial growth factor A 1.57546
BCL2 B-cell CLL/lymphoma 2 1.56706
HMOX1 heme oxygenase 1 1.54232
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.53456
IL6 interleukin 6 1.5113
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.50624
JUN jun proto-oncogene 1.47966
TP53 tumor protein p53 1.45194
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.45115
NOS2 nitric oxide synthase 2, inducible 1.43755
FOS FBJ murine osteosarcoma viral oncogene homolog 1.41911
SOD2 superoxide dismutase 2, mitochondrial 1.36933
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.36562
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.36533
PARP1 poly (ADP-ribose) polymerase 1 1.36447
CAT catalase 1.35041
FAS Fas cell surface death receptor 1.33966
MAPK1 mitogen-activated protein kinase 1 1.33375
TXNRD1 thioredoxin reductase 1 1.32726
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.32518
DDIT3 DNA-damage-inducible transcript 3 1.31387
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.28889
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.26545
GADD45A growth arrest and DNA-damage-inducible, alpha 1.26452
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.26205
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.25588
BCL2L1 BCL2-like 1 1.25152
MAPK3 mitogen-activated protein kinase 3 1.2456
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.24433
GSTP1 glutathione S-transferase pi 1 1.24275
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.23899
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.20163
IGF1 insulin-like growth factor 1 (somatomedin C) 1.19999
NQO1 NAD(P)H dehydrogenase, quinone 1 1.19574
TGFB1 transforming growth factor, beta 1 1.18948
BDNF brain-derived neurotrophic factor 1.17926
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.17728
TYMS thymidylate synthetase 1.15526
S100A4 S100 calcium binding protein A4 1.15022
NRP1 neuropilin 1 1.13518
H2AFX H2A histone family, member X 1.11911
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.11606
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.1136
GJA1 gap junction protein, alpha 1, 43kDa 1.1129
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.10734
MCL1 myeloid cell leukemia 1 1.10459
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.10353
EGR1 early growth response 1 1.09262
MCAM melanoma cell adhesion molecule 1.08904
CXCL8 chemokine (C-X-C motif) ligand 8 1.08655
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.08513
PPARG peroxisome proliferator-activated receptor gamma 1.07625
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.07093
CFLAR CASP8 and FADD-like apoptosis regulator 1.06952
CDK2 cyclin-dependent kinase 2 1.05648
BRCA1 breast cancer 1, early onset 1.05648
EGFR epidermal growth factor receptor 1.052
MMP2 matrix metallopeptidase 2 1.05052
ERBB2 erb-b2 receptor tyrosine kinase 2 1.04088
CCND1 cyclin D1 1.03567
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.03345
CD44 CD44 molecule (Indian blood group) 1.02746
COL1A2 collagen, type I, alpha 2 1.01776
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.01739
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.01625