Cellular response to hypoxia Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. (Gene Ontology, GO_0071456)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-2262749
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Genes

25 proteins participating in the Cellular response to hypoxia pathway from the Reactome Pathways dataset.

Symbol Name
ARNT aryl hydrocarbon receptor nuclear translocator
CA9 carbonic anhydrase IX
CREBBP CREB binding protein
CUL2 cullin 2
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIF3A hypoxia inducible factor 3, alpha subunit
RBX1 ring-box 1, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase