Carcinoma, Hepatocellular Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

195 genes associated with the Carcinoma, Hepatocellular phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AFP alpha-fetoprotein
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDOB aldolase B, fructose-bisphosphate
AR androgen receptor
AURKA aurora kinase A
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CABIN1 calcineurin binding protein 1
CASP14 caspase 14, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD34 CD34 molecule
CD80 CD80 molecule
CD81 CD81 molecule
CDC6 cell division cycle 6
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COMT catechol-O-methyltransferase
CRHR2 corticotropin releasing hormone receptor 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DLC1 DLC1 Rho GTPase activating protein
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGFR4 fibroblast growth factor receptor 4
FGL1 fibrinogen-like 1
GFRA1 GDNF family receptor alpha 1
GPX1 glutathione peroxidase 1
GRAP2 GRB2-related adaptor protein 2
GSTA1 glutathione S-transferase alpha 1
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTO1 glutathione S-transferase omega 1
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HDAC10 histone deacetylase 10
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IFI27 interferon, alpha-inducible protein 27
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL12A interleukin 12A
IL12RB1 interleukin 12 receptor, beta 1
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL4 interleukin 4
IL6 interleukin 6
INS insulin
ITGAV integrin, alpha V
JAK1 Janus kinase 1
KDR kinase insert domain receptor
KIF1B kinesin family member 1B
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLF6 Kruppel-like factor 6
LIPC lipase, hepatic
LTBP2 latent transforming growth factor beta binding protein 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR146A microRNA 146a
MIR196A2 microRNA 196a-2
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP21 matrix metallopeptidase 21
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSH2 mutS homolog 2
MT1X metallothionein 1X
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MX1 MX dynamin-like GTPase 1
MYH1 myosin, heavy chain 1, skeletal muscle, adult
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NQO1 NAD(P)H dehydrogenase, quinone 1
OGG1 8-oxoguanine DNA glycosylase
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PGD phosphogluconate dehydrogenase
PLA2G12B phospholipase A2, group XIIB
PPARA peroxisome proliferator-activated receptor alpha
PTCH1 patched 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RB1 retinoblastoma 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMYD3 SET and MYND domain containing 3
SOD2 superoxide dismutase 2, mitochondrial
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
THBS2 thrombospondin 2
THBS4 thrombospondin 4
TNF tumor necrosis factor
TP53 tumor protein p53
TYMS thymidylate synthetase
UBE4B ubiquitination factor E4B
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VKORC1 vitamin K epoxide reductase complex, subunit 1
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3