CP-863187-7558 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the CP-863187-7558 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACD adrenocortical dysplasia homolog (mouse)
ALMS1 Alstrom syndrome protein 1
ARHGAP19 Rho GTPase activating protein 19
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATXN3 ataxin 3
AXL AXL receptor tyrosine kinase
C16ORF45 chromosome 16 open reading frame 45
C9ORF114 chromosome 9 open reading frame 114
CA9 carbonic anhydrase IX
CALD1 caldesmon 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDK9 cyclin-dependent kinase 9
CDYL chromodomain protein, Y-like
CEP104 centrosomal protein 104kDa
CLCN3 chloride channel, voltage-sensitive 3
COBL cordon-bleu WH2 repeat protein
COX5B cytochrome c oxidase subunit Vb
CTAGE5 CTAGE family, member 5
CUL7 cullin 7
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DND1 DND microRNA-mediated repression inhibitor 1
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPOR erythropoietin receptor
EXTL3 exostosin-like glycosyltransferase 3
FAM20B family with sequence similarity 20, member B
GOSR2 golgi SNAP receptor complex member 2
GPALPP1 GPALPP motifs containing 1
GSDMB gasdermin B
HEATR6 HEAT repeat containing 6
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
IFI35 interferon-induced protein 35
IFT27 intraflagellar transport 27
IL6ST interleukin 6 signal transducer
INF2 inverted formin, FH2 and WH2 domain containing
KIAA1462 KIAA1462
KIF5C kinesin family member 5C
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPK7 mitogen-activated protein kinase 7
MAST3 microtubule associated serine/threonine kinase 3
MIA3 melanoma inhibitory activity family, member 3
MOB3B MOB kinase activator 3B
MOSPD2 motile sperm domain containing 2
MRPL52 mitochondrial ribosomal protein L52
MRPL57 mitochondrial ribosomal protein L57
MRPS11 mitochondrial ribosomal protein S11
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFIB nuclear factor I/B
NKTR natural killer cell triggering receptor
NNT nicotinamide nucleotide transhydrogenase
NUMB numb homolog (Drosophila)
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLCE1 phospholipase C, epsilon 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLXNA2 plexin A2
PNISR PNN-interacting serine/arginine-rich protein
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRSS8 protease, serine, 8
QKI QKI, KH domain containing, RNA binding
RANGAP1 Ran GTPase activating protein 1
RHOQ ras homolog family member Q
RPL13 ribosomal protein L13
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SETD4 SET domain containing 4
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIM2 single-minded family bHLH transcription factor 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC48A1 solute carrier family 48 (heme transporter), member 1
SOWAHC sosondowah ankyrin repeat domain family member C
SPTBN2 spectrin, beta, non-erythrocytic 2
SREBF2 sterol regulatory element binding transcription factor 2
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STARD3 StAR-related lipid transfer (START) domain containing 3
STK11 serine/threonine kinase 11
STX5 syntaxin 5
TAGLN3 transgelin 3
TEAD3 TEA domain family member 3
TMC6 transmembrane channel-like 6
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRADD TNFRSF1A-associated via death domain
TRAPPC6A trafficking protein particle complex 6A
TTC38 tetratricopeptide repeat domain 38
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WNT5A wingless-type MMTV integration site family, member 5A
XYLT2 xylosyltransferase II
ZNF137P zinc finger protein 137, pseudogene
ZNF180 zinc finger protein 180
ZNF324 zinc finger protein 324
ZNF358 zinc finger protein 358
ZNF574 zinc finger protein 574
ZNF764 zinc finger protein 764

decreased expression

Symbol Name
AHR aryl hydrocarbon receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APIP APAF1 interacting protein
ATAD5 ATPase family, AAA domain containing 5
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCL2L13 BCL2-like 13 (apoptosis facilitator)
C4ORF19 chromosome 4 open reading frame 19
CD53 CD53 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC37L1 cell division cycle 37-like 1
CDH7 cadherin 7, type 2
CDHR2 cadherin-related family member 2
CFAP69 cilia and flagella associated protein 69
CHML choroideremia-like (Rab escort protein 2)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COMMD10 COMM domain containing 10
CUTC cutC copper transporter
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCTN4 dynactin 4 (p62)
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DSE dermatan sulfate epimerase
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EXOC5 exocyst complex component 5
EXOSC1 exosome component 1
FAF1 Fas (TNFRSF6) associated factor 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBAS glioblastoma amplified sequence
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLDC glycine dehydrogenase (decarboxylating)
GLS2 glutaminase 2 (liver, mitochondrial)
GLT8D2 glycosyltransferase 8 domain containing 2
GPATCH1 G patch domain containing 1
GPATCH2L G patch domain containing 2-like
GPATCH3 G patch domain containing 3
GSR glutathione reductase
H1F0 H1 histone family, member 0
HIST1H2BI histone cluster 1, H2bi
HIST1H3H histone cluster 1, H3h
IFI44L interferon-induced protein 44-like
IL17RA interleukin 17 receptor A
ISL1 ISL LIM homeobox 1
LOC730101 uncharacterized LOC730101
LRRC49 leucine rich repeat containing 49
LYPD1 LY6/PLAUR domain containing 1
MAGEA6 melanoma antigen family A6
MANEA mannosidase, endo-alpha
MED9 mediator complex subunit 9
MLYCD malonyl-CoA decarboxylase
MOXD1 monooxygenase, DBH-like 1
NARFL nuclear prelamin A recognition factor-like
NHLRC2 NHL repeat containing 2
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PAIP2B poly(A) binding protein interacting protein 2B
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PTGFR prostaglandin F receptor (FP)
RARS arginyl-tRNA synthetase
RHBDD3 rhomboid domain containing 3
RIN1 Ras and Rab interactor 1
RNF39 ring finger protein 39
SCAI suppressor of cancer cell invasion
SCIN scinderin
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SH3BGR SH3 domain binding glutamate-rich protein
SLC16A6 solute carrier family 16, member 6
SNHG20 small nucleolar RNA host gene 20
SPATA7 spermatogenesis associated 7
STAC SH3 and cysteine rich domain
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN2 tectonic family member 2
TMEM183A transmembrane protein 183A
TRIM25 tripartite motif containing 25
TRIP11 thyroid hormone receptor interactor 11
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNKL unkempt family zinc finger-like
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
USP18 ubiquitin specific peptidase 18
USP20 ubiquitin specific peptidase 20
WNT10B wingless-type MMTV integration site family, member 10B
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZDHHC18 zinc finger, DHHC-type containing 18
ZMAT3 zinc finger, matrin-type 3
ZNF107 zinc finger protein 107
ZNF304 zinc finger protein 304
ZNF668 zinc finger protein 668
ZNF816 zinc finger protein 816