CP-320650-01-4560 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the CP-320650-01-4560 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADCK2 aarF domain containing kinase 2
AFF4 AF4/FMR2 family, member 4
AIM1L absent in melanoma 1-like
ALPPL2 alkaline phosphatase, placental-like 2
ANKH ANKH inorganic pyrophosphate transport regulator
ARMC4 armadillo repeat containing 4
ATAD5 ATPase family, AAA domain containing 5
ATG10 autophagy related 10
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BMP8B bone morphogenetic protein 8b
C17ORF53 chromosome 17 open reading frame 53
CBX8 chromobox homolog 8
CDK12 cyclin-dependent kinase 12
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFLAR CASP8 and FADD-like apoptosis regulator
CNOT4 CCR4-NOT transcription complex, subunit 4
COMMD4 COMM domain containing 4
COPS8 COP9 signalosome subunit 8
CREM cAMP responsive element modulator
DICER1 dicer 1, ribonuclease type III
DOCK5 dedicator of cytokinesis 5
E2F4 E2F transcription factor 4, p107/p130-binding
EGFR epidermal growth factor receptor
ESRRG estrogen-related receptor gamma
ETV1 ets variant 1
FBXO22 F-box protein 22
FGF5 fibroblast growth factor 5
FILIP1L filamin A interacting protein 1-like
FN1 fibronectin 1
FOXO4 forkhead box O4
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GK glycerol kinase
GMPR guanosine monophosphate reductase
HDAC11 histone deacetylase 11
HEG1 heart development protein with EGF-like domains 1
HOXB2 homeobox B2
IFNA14 interferon, alpha 14
IQCK IQ motif containing K
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA1024 KIAA1024
LAMP1 lysosomal-associated membrane protein 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100286895 cell division cycle 27 homolog pseudogene
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MZF1 myeloid zinc finger 1
NNT nicotinamide nucleotide transhydrogenase
ORC5 origin recognition complex, subunit 5
PAX2 paired box 2
PDE10A phosphodiesterase 10A
PLD1 phospholipase D1, phosphatidylcholine-specific
PLK4 polo-like kinase 4
POMT2 protein-O-mannosyltransferase 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB11B RAB11B, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
REEP1 receptor accessory protein 1
RGS10 regulator of G-protein signaling 10
RND1 Rho family GTPase 1
RNF6 ring finger protein (C3H2C3 type) 6
SARM1 sterile alpha and TIR motif containing 1
SCRN3 secernin 3
SIK3 SIK family kinase 3
SLA Src-like-adaptor
SOS2 son of sevenless homolog 2 (Drosophila)
SSBP2 single-stranded DNA binding protein 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST7L suppression of tumorigenicity 7 like
STMN4 stathmin-like 4
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D30 TBC1 domain family, member 30
TCEAL2 transcription elongation factor A (SII)-like 2
TCF3 transcription factor 3
TGFA transforming growth factor, alpha
TIAM2 T-cell lymphoma invasion and metastasis 2
TOP3B topoisomerase (DNA) III beta
TOR1AIP1 torsin A interacting protein 1
TRIM3 tripartite motif containing 3
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBE2B ubiquitin-conjugating enzyme E2B
UNC45A unc-45 homolog A (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VGLL3 vestigial-like family member 3
WDR55 WD repeat domain 55
WSB1 WD repeat and SOCS box containing 1
ZEB1 zinc finger E-box binding homeobox 1
ZFX zinc finger protein, X-linked
ZNF112 zinc finger protein 112
ZNF141 zinc finger protein 141
ZNF343 zinc finger protein 343
ZNF589 zinc finger protein 589
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATAT1 alpha tubulin acetyltransferase 1
ATXN2 ataxin 2
BAAT bile acid CoA:amino acid N-acyltransferase
C7ORF69 chromosome 7 open reading frame 69
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC9 coiled-coil domain containing 9
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKL3 cyclin-dependent kinase-like 3
CES3 carboxylesterase 3
CINP cyclin-dependent kinase 2 interacting protein
CLEC4E C-type lectin domain family 4, member E
COL9A2 collagen, type IX, alpha 2
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DUSP8 dual specificity phosphatase 8
EDAR ectodysplasin A receptor
EFCAB2 EF-hand calcium binding domain 2
EFNB1 ephrin-B1
FBXL7 F-box and leucine-rich repeat protein 7
FKTN fukutin
GJA8 gap junction protein, alpha 8, 50kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GPATCH2L G patch domain containing 2-like
HIST1H2AK histone cluster 1, H2ak
HIST1H2BJ histone cluster 1, H2bj
HIST1H3A histone cluster 1, H3a
HIST1H4D histone cluster 1, H4d
HSF2BP heat shock transcription factor 2 binding protein
IFT140 intraflagellar transport 140
IL12A interleukin 12A
IQSEC2 IQ motif and Sec7 domain 2
KIAA1107 KIAA1107
KIAA1456 KIAA1456
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
LATS1 large tumor suppressor kinase 1
LAX1 lymphocyte transmembrane adaptor 1
LMNB1 lamin B1
LOC729164 hCG1732469
LRP3 low density lipoprotein receptor-related protein 3
LRRK1 leucine-rich repeat kinase 1
MCC mutated in colorectal cancers
MFGE8 milk fat globule-EGF factor 8 protein
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MILR1 mast cell immunoglobulin-like receptor 1
MTA2 metastasis associated 1 family, member 2
MX1 MX dynamin-like GTPase 1
NABP2 nucleic acid binding protein 2
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
OSR2 odd-skipped related transciption factor 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PGPEP1 pyroglutamyl-peptidase I
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G1B phospholipase A2, group IB (pancreas)
PPL periplakin
PRSS53 protease, serine, 53
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPSN receptor-associated protein of the synapse
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
RUSC2 RUN and SH3 domain containing 2
SCNN1B sodium channel, non voltage gated 1 beta subunit
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERGEF secretion regulating guanine nucleotide exchange factor
SH3D21 SH3 domain containing 21
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLMO1 slowmo homolog 1 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
STAG3 stromal antigen 3
STARD3 StAR-related lipid transfer (START) domain containing 3
SUGCT succinyl-CoA:glutarate-CoA transferase
TICAM1 toll-like receptor adaptor molecule 1
TMCC2 transmembrane and coiled-coil domain family 2
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TTLL1 tubulin tyrosine ligase-like family member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
WDR62 WD repeat domain 62
ZHX2 zinc fingers and homeoboxes 2
ZNF358 zinc finger protein 358
ZNF574 zinc finger protein 574
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768
ZNF778 zinc finger protein 778