CP-320650-01-4557 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the CP-320650-01-4557 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRA2 adhesion G protein-coupled receptor A2
ADGRB3 adhesion G protein-coupled receptor B3
ADTRP androgen-dependent TFPI-regulating protein
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C2 aldo-keto reductase family 1, member C2
ANGPT4 angiopoietin 4
APAF1 apoptotic peptidase activating factor 1
ARHGAP26 Rho GTPase activating protein 26
BTN3A2 butyrophilin, subfamily 3, member A2
C14ORF93 chromosome 14 open reading frame 93
C20ORF195 chromosome 20 open reading frame 195
C5 complement component 5
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CISH cytokine inducible SH2-containing protein
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLCN7 chloride channel, voltage-sensitive 7
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CTNS cystinosin, lysosomal cystine transporter
CUL7 cullin 7
CYTH1 cytohesin 1
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP1 dual specificity phosphatase 1
ELSPBP1 epididymal sperm binding protein 1
FABP3 fatty acid binding protein 3, muscle and heart
FAM214B family with sequence similarity 214, member B
FBXL15 F-box and leucine-rich repeat protein 15
FDPS farnesyl diphosphate synthase
GAB1 GRB2-associated binding protein 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GK glycerol kinase
GLB1L galactosidase, beta 1-like
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRAMD1B GRAM domain containing 1B
GRAMD1C GRAM domain containing 1C
GREB1L growth regulation by estrogen in breast cancer-like
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
HBEGF heparin-binding EGF-like growth factor
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEG1 heart development protein with EGF-like domains 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL10 interleukin 10
IL11 interleukin 11
ING4 inhibitor of growth family, member 4
ISG20 interferon stimulated exonuclease gene 20kDa
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLK12 kallikrein-related peptidase 12
LIG3 ligase III, DNA, ATP-dependent
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MAP7 microtubule-associated protein 7
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTCP1 mature T-cell proliferation 1
NEBL nebulette
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSGIN2 oxidative stress induced growth inhibitor family member 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLCD1 phospholipase C, delta 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POU2F2 POU class 2 homeobox 2
PPARD peroxisome proliferator-activated receptor delta
PSD4 pleckstrin and Sec7 domain containing 4
PTHLH parathyroid hormone-like hormone
R3HDM1 R3H domain containing 1
RAD51 RAD51 recombinase
RBMS2 RNA binding motif, single stranded interacting protein 2
REC8 REC8 meiotic recombination protein
RGS5 regulator of G-protein signaling 5
RIMS1 regulating synaptic membrane exocytosis 1
RRAGD Ras-related GTP binding D
RTCA RNA 3'-terminal phosphate cyclase
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SMOX spermine oxidase
SRCAP Snf2-related CREBBP activator protein
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
TIMELESS timeless circadian clock
TRIM29 tripartite motif containing 29
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TYRO3 TYRO3 protein tyrosine kinase
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WSB1 WD repeat and SOCS box containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF141 zinc finger protein 141
ZNF219 zinc finger protein 219
ZNF234 zinc finger protein 234
ZNF609 zinc finger protein 609
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANKRD40 ankyrin repeat domain 40
APOL6 apolipoprotein L, 6
ARMCX4 armadillo repeat containing, X-linked 4
ASAP1-IT1 ASAP1 intronic transcript 1
ATAT1 alpha tubulin acetyltransferase 1
BAAT bile acid CoA:amino acid N-acyltransferase
BCL9 B-cell CLL/lymphoma 9
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF105 chromosome 1 open reading frame 105
C1ORF106 chromosome 1 open reading frame 106
C7ORF69 chromosome 7 open reading frame 69
CA11 carbonic anhydrase XI
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD101 CD101 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPED1 cadherin-like and PC-esterase domain containing 1
CTGF connective tissue growth factor
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DDN dendrin
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DMTN dematin actin binding protein
DNM3 dynamin 3
EML4 echinoderm microtubule associated protein like 4
FAT4 FAT atypical cadherin 4
GBX2 gastrulation brain homeobox 2
GJA8 gap junction protein, alpha 8, 50kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GREM1 gremlin 1, DAN family BMP antagonist
H2AFJ H2A histone family, member J
HIST1H4E histone cluster 1, H4e
HOXC4 homeobox C4
HYAL3 hyaluronoglucosaminidase 3
INHBB inhibin, beta B
IQSEC2 IQ motif and Sec7 domain 2
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIAA0513 KIAA0513
KLF2 Kruppel-like factor 2
KRT4 keratin 4, type II
LAX1 lymphocyte transmembrane adaptor 1
LMO7 LIM domain 7
LPPR4 lipid phosphate phosphatase-related protein type 4
MBTD1 mbt domain containing 1
MFSD12 major facilitator superfamily domain containing 12
MITF microphthalmia-associated transcription factor
MXD3 MAX dimerization protein 3
MXRA8 matrix-remodelling associated 8
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSBP2 oxysterol binding protein 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHC1 polyhomeotic homolog 1 (Drosophila)
PLAC8 placenta-specific 8
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRB3 proline-rich protein BstNI subfamily 3
PRICKLE3 prickle homolog 3 (Drosophila)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RAB17 RAB17, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RHOBTB1 Rho-related BTB domain containing 1
RIBC2 RIB43A domain with coiled-coils 2
RRP1 ribosomal RNA processing 1
RUNDC3B RUN domain containing 3B
SDC3 syndecan 3
SETBP1 SET binding protein 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLITRK5 SLIT and NTRK-like family, member 5
SLMO1 slowmo homolog 1 (Drosophila)
SMAD7 SMAD family member 7
SOX12 SRY (sex determining region Y)-box 12
SSBP3 single stranded DNA binding protein 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TENM1 teneurin transmembrane protein 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM132A transmembrane protein 132A
TNS2 tensin 2
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
YOD1 YOD1 deubiquitinase
ZBTB39 zinc finger and BTB domain containing 39
ZNF205 zinc finger protein 205
ZNF446 zinc finger protein 446
ZNF768 zinc finger protein 768