CP-319743-7537 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the CP-319743-7537 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADGRB2 adhesion G protein-coupled receptor B2
AHCYL2 adenosylhomocysteinase-like 2
AHI1 Abelson helper integration site 1
AKAP13 A kinase (PRKA) anchor protein 13
AKR1C2 aldo-keto reductase family 1, member C2
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P1 annexin A2 pseudogene 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP26 Rho GTPase activating protein 26
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ASTN2 astrotactin 2
ATAT1 alpha tubulin acetyltransferase 1
ATP11A ATPase, class VI, type 11A
BGN biglycan
C16ORF58 chromosome 16 open reading frame 58
C19ORF66 chromosome 19 open reading frame 66
C22ORF46 chromosome 22 open reading frame 46
C5ORF45 chromosome 5 open reading frame 45
CCDC57 coiled-coil domain containing 57
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK6 cyclin-dependent kinase 6
CEMIP cell migration inducing protein, hyaluronan binding
CLDN8 claudin 8
CNOT4 CCR4-NOT transcription complex, subunit 4
CPNE7 copine VII
CPZ carboxypeptidase Z
CRELD1 cysteine-rich with EGF-like domains 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
DDIT3 DNA-damage-inducible transcript 3
DDN dendrin
DFNB31 deafness, autosomal recessive 31
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EN2 engrailed homeobox 2
EXOC7 exocyst complex component 7
FAM214B family with sequence similarity 214, member B
FAM69A family with sequence similarity 69, member A
FGF23 fibroblast growth factor 23
FOXC1 forkhead box C1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H4D histone cluster 1, H4d
HMHA1 histocompatibility (minor) HA-1
HTATSF1 HIV-1 Tat specific factor 1
IL11 interleukin 11
IL11RA interleukin 11 receptor, alpha
IL6 interleukin 6
ISG20 interferon stimulated exonuclease gene 20kDa
IVNS1ABP influenza virus NS1A binding protein
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0319L KIAA0319-like
LIMD2 LIM domain containing 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNX1 motor neuron and pancreas homeobox 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYRF myelin regulatory factor
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARM1 prostate androgen-regulated mucin-like protein 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PNPLA4 patatin-like phospholipase domain containing 4
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
RNF146 ring finger protein 146
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPH3AL rabphilin 3A-like (without C2 domains)
SCAPER S-phase cyclin A-associated protein in the ER
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEPP1 selenoprotein P, plasma, 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMC1A structural maintenance of chromosomes 1A
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STC1 stanniocalcin 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBXA2R thromboxane A2 receptor
TCF4 transcription factor 4
TMEM2 transmembrane protein 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TSC22D2 TSC22 domain family, member 2
TUBA3C tubulin, alpha 3c
ULK1 unc-51 like autophagy activating kinase 1
USP19 ubiquitin specific peptidase 19
USP48 ubiquitin specific peptidase 48
WWOX WW domain containing oxidoreductase
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
AMT aminomethyltransferase
ANKRD36 ankyrin repeat domain 36
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ASTE1 asteroid homolog 1 (Drosophila)
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BTBD18 BTB (POZ) domain containing 18
C3ORF52 chromosome 3 open reading frame 52
C8ORF44 chromosome 8 open reading frame 44
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDON cell adhesion associated, oncogene regulated
CES3 carboxylesterase 3
CLDN14 claudin 14
CNTLN centlein, centrosomal protein
CORT cortistatin
CRYBA2 crystallin, beta A2
CRYGC crystallin, gamma C
CTC1 CTS telomere maintenance complex component 1
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DCAF17 DDB1 and CUL4 associated factor 17
DLK2 delta-like 2 homolog (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EIF5A2 eukaryotic translation initiation factor 5A2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETV6 ets variant 6
EXD3 exonuclease 3'-5' domain containing 3
FAM160B2 family with sequence similarity 160, member B2
FAM53B family with sequence similarity 53, member B
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FRMD8 FERM domain containing 8
GALT galactose-1-phosphate uridylyltransferase
GLB1L galactosidase, beta 1-like
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRPR gastrin-releasing peptide receptor
HDAC11 histone deacetylase 11
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HLA-DMA major histocompatibility complex, class II, DM alpha
HLX H2.0-like homeobox
HSF2BP heat shock transcription factor 2 binding protein
INCENP inner centromere protein antigens 135/155kDa
INHBB inhibin, beta B
LPAR3 lysophosphatidic acid receptor 3
LRP5L low density lipoprotein receptor-related protein 5-like
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCTP1 multiple C2 domains, transmembrane 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MMP1 matrix metallopeptidase 1
MOCS3 molybdenum cofactor synthesis 3
MOXD1 monooxygenase, DBH-like 1
MUC3A mucin 3A, cell surface associated
NME5 NME/NM23 family member 5
NOD1 nucleotide-binding oligomerization domain containing 1
NPY1R neuropeptide Y receptor Y1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OLFML2B olfactomedin-like 2B
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCOLCE procollagen C-endopeptidase enhancer
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLAC8 placenta-specific 8
PLK2 polo-like kinase 2
PODNL1 podocan-like 1
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PPT2 palmitoyl-protein thioesterase 2
PTX3 pentraxin 3, long
PUS1 pseudouridylate synthase 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RGS20 regulator of G-protein signaling 20
RHOBTB2 Rho-related BTB domain containing 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SAYSD1 SAYSVFN motif domain containing 1
SCHIP1 schwannomin interacting protein 1
SDC3 syndecan 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD8 SET domain containing (lysine methyltransferase) 8
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNHG3 small nucleolar RNA host gene 3
SNRPN small nuclear ribonucleoprotein polypeptide N
TAGLN3 transgelin 3
TEX40 testis expressed 40
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAPPC6A trafficking protein particle complex 6A
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UGT8 UDP glycosyltransferase 8
VSIG10 V-set and immunoglobulin domain containing 10
WNT7A wingless-type MMTV integration site family, member 7A
YAF2 YY1 associated factor 2
ZFP30 ZFP30 zinc finger protein
ZNF197 zinc finger protein 197
ZNF362 zinc finger protein 362
ZNF415 zinc finger protein 415
ZNF667 zinc finger protein 667
ZNF675 zinc finger protein 675
ZNF74 zinc finger protein 74