COPD - Chronic obstructive pulmonary disease_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE475 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE475
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Genes

600 genes differentially expressed during COPD - Chronic obstructive pulmonary disease_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE475 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
NPC1L1 NPC1-like 1 4.35452
GMPPA GDP-mannose pyrophosphorylase A 3.99288
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 3.92074
HAUS4 HAUS augmin-like complex, subunit 4 3.83601
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 3.80364
ZEB2 zinc finger E-box binding homeobox 2 3.80277
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 3.74136
MFSD11 major facilitator superfamily domain containing 11 3.70465
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 3.52334
TFDP1 transcription factor Dp-1 3.31843
CLSTN2 calsyntenin 2 3.25957
RFC4 replication factor C (activator 1) 4, 37kDa 3.24016
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 3.20664
RIPK4 receptor-interacting serine-threonine kinase 4 3.1368
SUGP2 SURP and G patch domain containing 2 3.10475
ZNF33B zinc finger protein 33B 3.06797
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 3.00556
UROS uroporphyrinogen III synthase 2.97549
TM2D1 TM2 domain containing 1 2.91793
METTL13 methyltransferase like 13 2.91699
IFNA6 interferon, alpha 6 2.91166
MR1 major histocompatibility complex, class I-related 2.91051
TRAF1 TNF receptor-associated factor 1 2.89895
PEX6 peroxisomal biogenesis factor 6 2.88446
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 2.86339
NOL11 nucleolar protein 11 2.85582
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.84906
SLAMF7 SLAM family member 7 2.84751
ASL argininosuccinate lyase 2.80468
TTYH1 tweety family member 1 2.77232
AGFG2 ArfGAP with FG repeats 2 2.76402
CHD9 chromodomain helicase DNA binding protein 9 2.73629
EPM2AIP1 EPM2A (laforin) interacting protein 1 2.68224
ASPHD1 aspartate beta-hydroxylase domain containing 1 2.66004
LY6H lymphocyte antigen 6 complex, locus H 2.63617
ZNF665 zinc finger protein 665 2.62379
AKAP9 A kinase (PRKA) anchor protein 9 2.62347
FBXW4 F-box and WD repeat domain containing 4 2.62163
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.62004
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.61138
CIDEC cell death-inducing DFFA-like effector c 2.5876
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1 2.57664
TSTA3 tissue specific transplantation antigen P35B 2.5761
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.5558
AHCTF1 AT hook containing transcription factor 1 2.55314
KIF25-AS1 KIF25 antisense RNA 1 2.54432
CASR calcium-sensing receptor 2.54222
C11ORF16 chromosome 11 open reading frame 16 2.533
FAM3A family with sequence similarity 3, member A 2.47122
CLDN11 claudin 11 2.46972
C2CD2L C2CD2-like 2.45538
CHN2 chimerin 2 2.43034
TRIM29 tripartite motif containing 29 2.42298
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 2.40822
TSSC1 tumor suppressing subtransferable candidate 1 2.40001
EBLN2 endogenous Bornavirus-like nucleoprotein 2 2.39879
EXOSC8 exosome component 8 2.37682
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 2.36753
SNX4 sorting nexin 4 2.3655
PELO pelota homolog (Drosophila) 2.36209
DDAH1 dimethylarginine dimethylaminohydrolase 1 2.35476
TRIM31 tripartite motif containing 31 2.32962
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2.32237
ZBTB32 zinc finger and BTB domain containing 32 2.3165
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 2.31232
TPCN1 two pore segment channel 1 2.31181
IPW imprinted in Prader-Willi syndrome (non-protein coding) 2.308
NENF neudesin neurotrophic factor 2.30698
PTGES3L-AARSD1 PTGES3L-AARSD1 readthrough 2.29459
PPCDC phosphopantothenoylcysteine decarboxylase 2.29127
HMBS hydroxymethylbilane synthase 2.28783
CRLF1 cytokine receptor-like factor 1 2.28693
ARHGAP32 Rho GTPase activating protein 32 2.28346
NCAPH non-SMC condensin I complex, subunit H 2.28051
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.2659
NADK NAD kinase 2.26378
PURA purine-rich element binding protein A 2.25576
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 2.25423
SNUPN snurportin 1 2.24727
ZNF93 zinc finger protein 93 2.24232
CLEC2D C-type lectin domain family 2, member D 2.2413
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.23199
GPR19 G protein-coupled receptor 19 2.23148
OCLN occludin 2.2257
CRLF2 cytokine receptor-like factor 2 2.22514
SPATA6 spermatogenesis associated 6 2.21497
ILVBL ilvB (bacterial acetolactate synthase)-like 2.20917
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 2.17154
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 2.14689
FGF8 fibroblast growth factor 8 (androgen-induced) 2.14118
DAPK2 death-associated protein kinase 2 2.13628
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 2.12757
KIF21B kinesin family member 21B 2.12592
NOVA2 neuro-oncological ventral antigen 2 2.11953
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 2.11614
RBM10 RNA binding motif protein 10 2.11301
APC adenomatous polyposis coli 2.1088
KLRK1 killer cell lectin-like receptor subfamily K, member 1 2.10495
SPRYD7 SPRY domain containing 7 2.10397
ZNF14 zinc finger protein 14 2.08086
CHP2 calcineurin-like EF-hand protein 2 2.08056
FZD5 frizzled class receptor 5 2.07608
PLEKHA6 pleckstrin homology domain containing, family A member 6 2.07392
BUD31 BUD31 homolog (S. cerevisiae) 2.06451
LMAN1L lectin, mannose-binding, 1 like 2.06444
GSTM5 glutathione S-transferase mu 5 2.06309
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.06239
SDF2 stromal cell-derived factor 2 2.06136
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 2.0562
NSUN7 NOP2/Sun domain family, member 7 2.05369
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 2.05363
HBQ1 hemoglobin, theta 1 2.05008
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 2.04105
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.03644
TUFM Tu translation elongation factor, mitochondrial 2.03539
C19ORF40 chromosome 19 open reading frame 40 2.03514
CR2 complement component (3d/Epstein Barr virus) receptor 2 2.03349
ALPI alkaline phosphatase, intestinal 2.03304
IER3IP1 immediate early response 3 interacting protein 1 2.01773
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 2.01562
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.01523
ALOX15B arachidonate 15-lipoxygenase, type B 2.00501
SEPHS2 selenophosphate synthetase 2 1.99621
CKB creatine kinase, brain 1.99432
GRB2 growth factor receptor-bound protein 2 1.99163
HDAC4 histone deacetylase 4 1.985
ZNF133 zinc finger protein 133 1.97292
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 1.96915
KLK13 kallikrein-related peptidase 13 1.96686
TBXA2R thromboxane A2 receptor 1.9604
ZNF10 zinc finger protein 10 1.95482
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.95283
TMEM163 transmembrane protein 163 1.94234
TECPR2 tectonin beta-propeller repeat containing 2 1.93102
CYB5A cytochrome b5 type A (microsomal) 1.92027
TRIM24 tripartite motif containing 24 1.91431
TMEM63A transmembrane protein 63A 1.90868
ZNF268 zinc finger protein 268 1.90538
SIGLEC9 sialic acid binding Ig-like lectin 9 1.89325
MOG myelin oligodendrocyte glycoprotein 1.89259
SLC25A38 solute carrier family 25, member 38 1.89212
EP300 E1A binding protein p300 1.88987
PSD3 pleckstrin and Sec7 domain containing 3 1.88827
FAM149B1 family with sequence similarity 149, member B1 1.88714
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.88292
DDIT3 DNA-damage-inducible transcript 3 1.87996
CRTAC1 cartilage acidic protein 1 1.87274
DMTF1 cyclin D binding myb-like transcription factor 1 1.87205
STX11 syntaxin 11 1.87121
CARD10 caspase recruitment domain family, member 10 1.87
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 1.86487
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.86188
LARS leucyl-tRNA synthetase 1.85945
CERS6 ceramide synthase 6 1.85413
AIM2 absent in melanoma 2 1.85077
CYB5R2 cytochrome b5 reductase 2 1.84981
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 1.845
PARK2 parkin RBR E3 ubiquitin protein ligase 1.84422
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 1.84151
REG1P regenerating islet-derived 1 pseudogene 1.83758
UNC119 unc-119 homolog (C. elegans) 1.82568
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) 1.82515
EP400 E1A binding protein p400 1.82285
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 1.81396
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.81225
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 1.80919
PTEN phosphatase and tensin homolog 1.80522
PSAT1 phosphoserine aminotransferase 1 1.79769
CIR1 corepressor interacting with RBPJ, 1 1.79187
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 1.78767
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.78695
ZSWIM1 zinc finger, SWIM-type containing 1 1.78682
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 1.78153
COL11A2 collagen, type XI, alpha 2 1.78056
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 1.77126
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.76994
LRTM1 leucine-rich repeats and transmembrane domains 1 1.76197
CETN3 centrin, EF-hand protein, 3 1.75779
GPX4 glutathione peroxidase 4 1.75771
CCDC90B coiled-coil domain containing 90B 1.75697
DPH2 DPH2 homolog (S. cerevisiae) 1.75589
STAR steroidogenic acute regulatory protein 1.75431
BPY2 basic charge, Y-linked, 2 1.75411
LTN1 listerin E3 ubiquitin protein ligase 1 1.75099
DCHS2 dachsous cadherin-related 2 1.74918
ZNF672 zinc finger protein 672 1.7486
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 1.7477
ERI2 ERI1 exoribonuclease family member 2 1.74525
NR2C1 nuclear receptor subfamily 2, group C, member 1 1.74328
CABP2 calcium binding protein 2 1.73312
FAM127A family with sequence similarity 127, member A 1.73225
PCCA propionyl CoA carboxylase, alpha polypeptide 1.72951
TRBV21-1 T cell receptor beta variable 21-1 (pseudogene) 1.7285
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 1.72616
MDFIC MyoD family inhibitor domain containing 1.72095
ZNF175 zinc finger protein 175 1.71594
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 1.71523
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1.71304
GEMIN6 gem (nuclear organelle) associated protein 6 1.70895
SASH3 SAM and SH3 domain containing 3 1.70761
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 1.70477
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 1.6964
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 1.69449
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 1.69418
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional) 1.6937
GOT2P1 glutamic-oxaloacetic transaminase 2 pseudogene 1 1.68665
OR2F2 olfactory receptor, family 2, subfamily F, member 2 1.68459
RABEPK Rab9 effector protein with kelch motifs 1.68308
FGFR4 fibroblast growth factor receptor 4 1.68184
FLRT1 fibronectin leucine rich transmembrane protein 1 1.68135
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 1.67841
NCOA3 nuclear receptor coactivator 3 1.67727
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 1.6766
OLIG2 oligodendrocyte lineage transcription factor 2 1.67443
TMPRSS6 transmembrane protease, serine 6 1.669
BBS4 Bardet-Biedl syndrome 4 1.6681
VAMP5 vesicle-associated membrane protein 5 1.66729
RASA4 RAS p21 protein activator 4 1.6658
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.66025
CUL9 cullin 9 1.65991
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 1.64811
PDE8B phosphodiesterase 8B 1.64655
ZNF428 zinc finger protein 428 1.64638
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 1.64484
TLN2 talin 2 1.64021
PIBF1 progesterone immunomodulatory binding factor 1 1.63774
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 1.63273
GYG2 glycogenin 2 1.63036
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 1.6291
BOK BCL2-related ovarian killer 1.62579
ACOT8 acyl-CoA thioesterase 8 1.62576
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 1.62527
FRYL FRY-like 1.62509
S100G S100 calcium binding protein G 1.62406
RER1 retention in endoplasmic reticulum sorting receptor 1 1.62373
F2RL3 coagulation factor II (thrombin) receptor-like 3 1.62024
TUBD1 tubulin, delta 1 1.61957
HDAC6 histone deacetylase 6 1.61878
DDHD2 DDHD domain containing 2 1.61821
CEP70 centrosomal protein 70kDa 1.61702
ICMT isoprenylcysteine carboxyl methyltransferase 1.61594
KLK5 kallikrein-related peptidase 5 1.61567
ATXN7 ataxin 7 1.61499
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.61256
ADI1 acireductone dioxygenase 1 1.61155
RGS6 regulator of G-protein signaling 6 1.61066
NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.61029
GAP43 growth associated protein 43 1.60966
CXXC1 CXXC finger protein 1 1.60677
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 1.60657
CBX2 chromobox homolog 2 1.60301
KIAA0141 KIAA0141 1.60201
MYO7B myosin VIIB 1.60182
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.60033
CAB39 calcium binding protein 39 1.59824
PKP3 plakophilin 3 1.59569
PEX3 peroxisomal biogenesis factor 3 1.59464
ACE2 angiotensin I converting enzyme 2 1.59245
ESM1 endothelial cell-specific molecule 1 1.59188
OLAH oleoyl-ACP hydrolase 1.59042
RPS19 ribosomal protein S19 1.58989
GBX2 gastrulation brain homeobox 2 1.5895
SRPK3 SRSF protein kinase 3 1.58362
UBL5 ubiquitin-like 5 1.581
ACAD10 acyl-CoA dehydrogenase family, member 10 1.57555
KAT6B K(lysine) acetyltransferase 6B 1.57492
SEC14L5 SEC14-like 5 (S. cerevisiae) 1.57126
TRO trophinin 1.56955
ZNF350 zinc finger protein 350 1.56624
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding) 1.56199
PDZRN3 PDZ domain containing ring finger 3 1.56116
GDF11 growth differentiation factor 11 1.55926
ST7L suppression of tumorigenicity 7 like 1.55706
SLC48A1 solute carrier family 48 (heme transporter), member 1 1.55366
KIAA1107 KIAA1107 1.5525
COL13A1 collagen, type XIII, alpha 1 1.55206
WRB tryptophan rich basic protein 1.55025
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 1.54963
DGKB diacylglycerol kinase, beta 90kDa 1.54876
ZNF358 zinc finger protein 358 1.54493
ZNF721 zinc finger protein 721 1.54351
POU2F2 POU class 2 homeobox 2 1.54288
MFN1 mitofusin 1 1.54227
HPX hemopexin 1.542
C22ORF46 chromosome 22 open reading frame 46 1.5384
GOSR2 golgi SNAP receptor complex member 2 1.53475
KIAA1456 KIAA1456 1.53337
CLCNKB chloride channel, voltage-sensitive Kb 1.53196
FAM63B family with sequence similarity 63, member B 1.53153
CNOT8 CCR4-NOT transcription complex, subunit 8 1.53067
TBC1D22A TBC1 domain family, member 22A 1.53063
HIC2 hypermethylated in cancer 2 1.52925
LINC00339 long intergenic non-protein coding RNA 339 1.52799
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 1.52352
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.52334
BCOR BCL6 corepressor 1.51966
CA6 carbonic anhydrase VI 1.51608
TTLL5 tubulin tyrosine ligase-like family member 5 1.5159
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.50997
PCDHA12 protocadherin alpha 12 1.50991

decreased expression

Symbol Name Standardized Value
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -3.10558
INTS6 integrator complex subunit 6 -2.94806
KHDC1 KH homology domain containing 1 -2.53523
L1CAM L1 cell adhesion molecule -2.47818
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -2.41409
SELPLG selectin P ligand -2.35497
APOL6 apolipoprotein L, 6 -2.31358
DRG2 developmentally regulated GTP binding protein 2 -2.26389
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 -2.14171
OXT oxytocin/neurophysin I prepropeptide -2.12753
ADA adenosine deaminase -2.09792
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.09684
PDE2A phosphodiesterase 2A, cGMP-stimulated -2.04307
PPP1R7 protein phosphatase 1, regulatory subunit 7 -2.03248
TSC22D1 TSC22 domain family, member 1 -2.02855
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.02205
POMT1 protein-O-mannosyltransferase 1 -1.97793
HPR haptoglobin-related protein -1.96188
HOXD3 homeobox D3 -1.95802
TMEM74B transmembrane protein 74B -1.94755
TSPAN8 tetraspanin 8 -1.93792
IGLV3-19 immunoglobulin lambda variable 3-19 -1.89771
CCNB2 cyclin B2 -1.89162
CASP8 caspase 8, apoptosis-related cysteine peptidase -1.86768
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -1.86544
WWC2 WW and C2 domain containing 2 -1.85899
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -1.85616
SNRK SNF related kinase -1.786
LEPROT leptin receptor overlapping transcript -1.77602
BDNF brain-derived neurotrophic factor -1.75234
FN3K fructosamine 3 kinase -1.70037
KCTD14 potassium channel tetramerization domain containing 14 -1.69742
NR2F1 nuclear receptor subfamily 2, group F, member 1 -1.66206
EXTL3 exostosin-like glycosyltransferase 3 -1.64851
CD40LG CD40 ligand -1.64092
JARID2 jumonji, AT rich interactive domain 2 -1.61681
TPSD1 tryptase delta 1 -1.59389
BATF basic leucine zipper transcription factor, ATF-like -1.58824
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -1.56688
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -1.55793
ICAM2 intercellular adhesion molecule 2 -1.55411
TEP1 telomerase-associated protein 1 -1.54937
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -1.54545
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -1.54504
METAP2 methionyl aminopeptidase 2 -1.50304
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -1.50207
CLIP3 CAP-GLY domain containing linker protein 3 -1.49972
CBX4 chromobox homolog 4 -1.4994
PLCD1 phospholipase C, delta 1 -1.49807
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial -1.48587
GJA4 gap junction protein, alpha 4, 37kDa -1.46565
ZNF440 zinc finger protein 440 -1.46264
BHMT betaine--homocysteine S-methyltransferase -1.45074
BCL7A B-cell CLL/lymphoma 7A -1.43867
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -1.43454
NANS N-acetylneuraminic acid synthase -1.43395
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -1.43052
PRKCSH protein kinase C substrate 80K-H -1.4134
C7ORF25 chromosome 7 open reading frame 25 -1.37544
NOP14-AS1 NOP14 antisense RNA 1 -1.36525
APC2 adenomatosis polyposis coli 2 -1.36151
DNAH9 dynein, axonemal, heavy chain 9 -1.3592
RBBP6 retinoblastoma binding protein 6 -1.35385
GREB1 growth regulation by estrogen in breast cancer 1 -1.35344
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -1.35041
CORO2A coronin, actin binding protein, 2A -1.34478
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -1.34049
ZIC4 Zic family member 4 -1.33305
SOX4 SRY (sex determining region Y)-box 4 -1.32937
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -1.3283
PROZ protein Z, vitamin K-dependent plasma glycoprotein -1.32726
CPT1A carnitine palmitoyltransferase 1A (liver) -1.32025
ENDOU endonuclease, polyU-specific -1.31743
ERO1LB ERO1-like beta (S. cerevisiae) -1.31559
KLF10 Kruppel-like factor 10 -1.31473
TBX21 T-box 21 -1.31339
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -1.30944
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) -1.30835
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -1.30451
SELE selectin E -1.29854
CD40 CD40 molecule, TNF receptor superfamily member 5 -1.29075
PHF21A PHD finger protein 21A -1.29073
IGLJ3 immunoglobulin lambda joining 3 -1.27808
EMC1 ER membrane protein complex subunit 1 -1.2767
GPR162 G protein-coupled receptor 162 -1.27558
NRN1 neuritin 1 -1.27515
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -1.27332
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -1.27059
CDK6 cyclin-dependent kinase 6 -1.26854
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -1.26501
TRIM28 tripartite motif containing 28 -1.2562
UBE2I ubiquitin-conjugating enzyme E2I -1.24805
PGRMC1 progesterone receptor membrane component 1 -1.24752
CHMP1A charged multivesicular body protein 1A -1.24684
ZC3H7A zinc finger CCCH-type containing 7A -1.24139
PIR pirin (iron-binding nuclear protein) -1.23508
PDLIM2 PDZ and LIM domain 2 (mystique) -1.23407
SHH sonic hedgehog -1.22127
FGA fibrinogen alpha chain -1.22117
CCDC70 coiled-coil domain containing 70 -1.20398
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -1.19676
SNX5 sorting nexin 5 -1.19621
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -1.19595
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 -1.19202
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -1.18998
ASCL3 achaete-scute family bHLH transcription factor 3 -1.18272
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -1.18257
MAG myelin associated glycoprotein -1.18207
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -1.17515
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -1.16846
SH3GL2 SH3-domain GRB2-like 2 -1.16614
ZC3H14 zinc finger CCCH-type containing 14 -1.16492
PQLC2 PQ loop repeat containing 2 -1.1585
LDB2 LIM domain binding 2 -1.1573
TENM3 teneurin transmembrane protein 3 -1.14612
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit -1.141
FOXD4L1 forkhead box D4-like 1 -1.14029
C6ORF120 chromosome 6 open reading frame 120 -1.1308
PDS5B PDS5 cohesin associated factor B -1.12384
CSNK1G1 casein kinase 1, gamma 1 -1.11847
GABPA GA binding protein transcription factor, alpha subunit 60kDa -1.11765
CKAP2 cytoskeleton associated protein 2 -1.11679
OSGIN1 oxidative stress induced growth inhibitor 1 -1.11663
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -1.1155
KSR1 kinase suppressor of ras 1 -1.10781
SH3GLB2 SH3-domain GRB2-like endophilin B2 -1.10666
CA3 carbonic anhydrase III -1.10357
GATAD2A GATA zinc finger domain containing 2A -1.0999
GCC2 GRIP and coiled-coil domain containing 2 -1.09984
PLCB4 phospholipase C, beta 4 -1.09703
WDR74 WD repeat domain 74 -1.09234
EXOSC2 exosome component 2 -1.0914
PAX1 paired box 1 -1.0902
HIC1 hypermethylated in cancer 1 -1.08955
MBD6 methyl-CpG binding domain protein 6 -1.08757
ZNF3 zinc finger protein 3 -1.08585
NRL neural retina leucine zipper -1.08359
ZDHHC18 zinc finger, DHHC-type containing 18 -1.07977
UVRAG UV radiation resistance associated -1.07931
BPESC1 blepharophimosis, epicanthus inversus and ptosis, candidate 1 (non-protein coding) -1.07834
ATP9B ATPase, class II, type 9B -1.07363
PFDN6 prefoldin subunit 6 -1.06985
KDM6B lysine (K)-specific demethylase 6B -1.06856
NRXN1 neurexin 1 -1.06556
SUMO2 small ubiquitin-like modifier 2 -1.0651
DESI1 desumoylating isopeptidase 1 -1.06501
ZNF135 zinc finger protein 135 -1.06459
PISD phosphatidylserine decarboxylase -1.06207
RAD52 RAD52 homolog (S. cerevisiae) -1.05668
LRRC15 leucine rich repeat containing 15 -1.05548
ACSM2B acyl-CoA synthetase medium-chain family member 2B -1.0523
PPP1R16B protein phosphatase 1, regulatory subunit 16B -1.05161
FN3KRP fructosamine 3 kinase related protein -1.05056
HPSE2 heparanase 2 (inactive) -1.04856
MEF2BNB MEF2B neighbor -1.04831
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -1.04698
PKP2 plakophilin 2 -1.04614
FNBP4 formin binding protein 4 -1.04216
BCL7B B-cell CLL/lymphoma 7B -1.0411
MLEC malectin -1.03628
TYRP1 tyrosinase-related protein 1 -1.03384
RING1 ring finger protein 1 -1.03342
IL6 interleukin 6 -1.03281
SMYD2 SET and MYND domain containing 2 -1.031
LIMK1 LIM domain kinase 1 -1.03066
SIRT7 sirtuin 7 -1.02462
GRB10 growth factor receptor-bound protein 10 -1.02049
TLN1 talin 1 -1.01829
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -1.01617
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa -1.01424
CDK7 cyclin-dependent kinase 7 -1.0128
PRKD3 protein kinase D3 -1.01206
MID1 midline 1 -1.00945
APOLD1 apolipoprotein L domain containing 1 -1.00663
SMA4 glucuronidase, beta pseudogene -1.0062
SREK1IP1 SREK1-interacting protein 1 -1.00423
GPR20 G protein-coupled receptor 20 -1.00243
KIAA1109 KIAA1109 -0.996463
POLR1E polymerase (RNA) I polypeptide E, 53kDa -0.995559
RORC RAR-related orphan receptor C -0.994611
NKAIN1 Na+/K+ transporting ATPase interacting 1 -0.993487
IGFBP3 insulin-like growth factor binding protein 3 -0.992362
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.990058
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -0.984276
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.984247
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -0.983074
IL6R interleukin 6 receptor -0.98244
FCMR Fc fragment of IgM receptor -0.978364
ADH6 alcohol dehydrogenase 6 (class V) -0.975828
IREB2 iron-responsive element binding protein 2 -0.975113
ZBTB6 zinc finger and BTB domain containing 6 -0.974048
ZMYM5 zinc finger, MYM-type 5 -0.973888
CHMP2B charged multivesicular body protein 2B -0.972509
MZF1 myeloid zinc finger 1 -0.97187
CCL3 chemokine (C-C motif) ligand 3 -0.968442
PIGA phosphatidylinositol glycan anchor biosynthesis, class A -0.966354
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -0.965196
TXN thioredoxin -0.960111
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -0.957925
COL4A4 collagen, type IV, alpha 4 -0.956905
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.956847
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -0.956819
PSAP prosaposin -0.954866
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -0.949635
ULK2 unc-51 like autophagy activating kinase 2 -0.945727
CLDN5 claudin 5 -0.944978
CREM cAMP responsive element modulator -0.944702
PEG3 paternally expressed 3 -0.944443
APOL2 apolipoprotein L, 2 -0.94288
TRDV3 T cell receptor delta variable 3 -0.942681
EXOC7 exocyst complex component 7 -0.9405
ITGB1BP1 integrin beta 1 binding protein 1 -0.938876
DEFA5 defensin, alpha 5, Paneth cell-specific -0.935644
C1ORF159 chromosome 1 open reading frame 159 -0.934885
JPH2 junctophilin 2 -0.932439
AK4 adenylate kinase 4 -0.932214
KLHL36 kelch-like family member 36 -0.932122
PCDHA5 protocadherin alpha 5 -0.930395
SNAI1 snail family zinc finger 1 -0.93003
NCR1 natural cytotoxicity triggering receptor 1 -0.928956
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.928725
NCOA6 nuclear receptor coactivator 6 -0.923806
SLTM SAFB-like, transcription modulator -0.922089
TRIM65 tripartite motif containing 65 -0.921078
AAMP angio-associated, migratory cell protein -0.920957
KIAA1217 KIAA1217 -0.913997
DIAPH2 diaphanous-related formin 2 -0.911944
CDH8 cadherin 8, type 2 -0.911622
FOXA2 forkhead box A2 -0.910968
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -0.910713
AURKB aurora kinase B -0.910085
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -0.909807
THUMPD1 THUMP domain containing 1 -0.908763
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -0.908321
FBXO28 F-box protein 28 -0.907091
SIRPA signal-regulatory protein alpha -0.906173
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.904612
KRT36 keratin 36, type I -0.901564
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -0.901424
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.901291
FGD6 FYVE, RhoGEF and PH domain containing 6 -0.898746
MMP9 matrix metallopeptidase 9 -0.896755
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.896239
GATA4 GATA binding protein 4 -0.895968
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -0.895198
SYNJ2 synaptojanin 2 -0.894605
CYCSP44 cytochrome c, somatic pseudogene 44 -0.890159
GPATCH1 G patch domain containing 1 -0.89013
VAV2 vav 2 guanine nucleotide exchange factor -0.889992
RBM42 RNA binding motif protein 42 -0.889892
RTN3 reticulon 3 -0.889354
KLF2 Kruppel-like factor 2 -0.887913
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -0.885645
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -0.88502
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.884046
ANAPC1 anaphase promoting complex subunit 1 -0.882337
SIN3B SIN3 transcription regulator family member B -0.882182
GSDMD gasdermin D -0.881553
SNX19 sorting nexin 19 -0.881055
PNPLA3 patatin-like phospholipase domain containing 3 -0.880726
RGPD5 RANBP2-like and GRIP domain containing 5 -0.880597
CLCA1 chloride channel accessory 1 -0.879608
ZNF24 zinc finger protein 24 -0.87951
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.875287
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene -0.874172
CLK3 CDC-like kinase 3 -0.873836
MUC6 mucin 6, oligomeric mucus/gel-forming -0.869981
ZFAND5 zinc finger, AN1-type domain 5 -0.869846
PLXNB2 plexin B2 -0.868793
HPN hepsin -0.868365
ZNF821 zinc finger protein 821 -0.867467
ABHD6 abhydrolase domain containing 6 -0.86674
MEIS3P1 Meis homeobox 3 pseudogene 1 -0.865164
RUFY1 RUN and FYVE domain containing 1 -0.865072
PIGR polymeric immunoglobulin receptor -0.865052
SETD6 SET domain containing 6 -0.8649
SLC44A1 solute carrier family 44 (choline transporter), member 1 -0.863931
PKM pyruvate kinase, muscle -0.863497
ERCC8 excision repair cross-complementation group 8 -0.863226
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -0.860278
TMEM248 transmembrane protein 248 -0.856828
KIAA0754 KIAA0754 -0.856792
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -0.856369
PCNA proliferating cell nuclear antigen -0.855324
CROCC ciliary rootlet coiled-coil, rootletin -0.854779
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -0.854105
AFTPH aftiphilin -0.85369
ELMO2 engulfment and cell motility 2 -0.853577
TTC36 tetratricopeptide repeat domain 36 -0.853543
TBC1D30 TBC1 domain family, member 30 -0.85222
NPY1R neuropeptide Y receptor Y1 -0.852167
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -0.849212
PEX5L peroxisomal biogenesis factor 5-like -0.848114
SMC6 structural maintenance of chromosomes 6 -0.847279
NR1H3 nuclear receptor subfamily 1, group H, member 3 -0.847231
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.846656
IRF1 interferon regulatory factor 1 -0.846348
SPAG5 sperm associated antigen 5 -0.845695
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -0.844388
NOTCH3 notch 3 -0.84312