COPD - Chronic obstructive pulmonary disease_Lung Tissue_GSE1650 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1650
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Genes

600 genes differentially expressed during COPD - Chronic obstructive pulmonary disease_Lung Tissue_GSE1650 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 3.28597
EEF2 eukaryotic translation elongation factor 2 2.9367
SERP1 stress-associated endoplasmic reticulum protein 1 2.89694
PTGDS prostaglandin D2 synthase 21kDa (brain) 2.78276
NR2F1 nuclear receptor subfamily 2, group F, member 1 2.75566
RPS8 ribosomal protein S8 2.72992
P4HB prolyl 4-hydroxylase, beta polypeptide 2.70852
CCDC73 coiled-coil domain containing 73 2.6748
COA3 cytochrome c oxidase assembly factor 3 2.6109
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 2.60966
SDC1 syndecan 1 2.50563
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E 2.48103
CCNI cyclin I 2.40768
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 2.40274
CHRDL1 chordin-like 1 2.40206
C1S complement component 1, s subcomponent 2.3853
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2.38239
C1R complement component 1, r subcomponent 2.3813
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 2.37992
PUM1 pumilio RNA-binding family member 1 2.37638
MGP matrix Gla protein 2.36877
CUEDC2 CUE domain containing 2 2.36364
ANXA6 annexin A6 2.32231
CEP350 centrosomal protein 350kDa 2.32024
NME2 NME/NM23 nucleoside diphosphate kinase 2 2.31123
KPNB1 karyopherin (importin) beta 1 2.29427
SERF2 small EDRK-rich factor 2 2.28334
CHD4 chromodomain helicase DNA binding protein 4 2.28297
NDUFA4 NDUFA4, mitochondrial complex associated 2.26234
BTG1 B-cell translocation gene 1, anti-proliferative 2.25962
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 2.25262
NME1 NME/NM23 nucleoside diphosphate kinase 1 2.23856
MORF4L2 mortality factor 4 like 2 2.23176
REPIN1 replication initiator 1 2.23176
LAPTM4A lysosomal protein transmembrane 4 alpha 2.21472
NFRKB nuclear factor related to kappaB binding protein 2.20223
SNRPE small nuclear ribonucleoprotein polypeptide E 2.20103
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 2.19443
RGL1 ral guanine nucleotide dissociation stimulator-like 1 2.1884
CCDC64B coiled-coil domain containing 64B 2.18125
SEC61G Sec61 gamma subunit 2.17889
FAM98A family with sequence similarity 98, member A 2.17198
NME4 NME/NM23 nucleoside diphosphate kinase 4 2.16808
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 2.16704
WDR82 WD repeat domain 82 2.16405
LARS leucyl-tRNA synthetase 2.15147
CABIN1 calcineurin binding protein 1 2.13463
MFAP4 microfibrillar-associated protein 4 2.13256
TXNL1 thioredoxin-like 1 2.12143
MXRA8 matrix-remodelling associated 8 2.12104
ASS1 argininosuccinate synthase 1 2.11986
KARS lysyl-tRNA synthetase 2.11084
SECISBP2 SECIS binding protein 2 2.09238
SRPRB signal recognition particle receptor, B subunit 2.08704
DRAM1 DNA-damage regulated autophagy modulator 1 2.07323
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 2.06906
OSBPL8 oxysterol binding protein-like 8 2.06028
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 2.05538
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 2.05354
LUM lumican 2.0508
ARMCX3 armadillo repeat containing, X-linked 3 2.05009
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.04815
MRC2 mannose receptor, C type 2 2.04755
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 2.04433
CSRP1 cysteine and glycine-rich protein 1 2.02894
ESD esterase D 2.02066
ITGAV integrin, alpha V 2.01819
PITRM1 pitrilysin metallopeptidase 1 2.01646
LAPTM4B lysosomal protein transmembrane 4 beta 2.01046
TSPAN4 tetraspanin 4 2.00927
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.99572
SUMO2 small ubiquitin-like modifier 2 1.99005
TMEM214 transmembrane protein 214 1.98841
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 1.97548
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1.97105
PBX1 pre-B-cell leukemia homeobox 1 1.96388
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 1.95935
SLIT3 slit homolog 3 (Drosophila) 1.95106
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 1.94913
ICAM3 intercellular adhesion molecule 3 1.94686
MALL mal, T-cell differentiation protein-like 1.94081
NUP43 nucleoporin 43kDa 1.93858
LARP1 La ribonucleoprotein domain family, member 1 1.92103
NAP1L1 nucleosome assembly protein 1-like 1 1.91987
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 1.91513
NCL nucleolin 1.9074
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 1.90058
GSTA4 glutathione S-transferase alpha 4 1.89915
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 1.89736
CES2 carboxylesterase 2 1.87868
HP haptoglobin 1.87775
RNF11 ring finger protein 11 1.87368
TOR1A torsin family 1, member A (torsin A) 1.86774
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.86302
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 1.85726
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 1.85575
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 1.85559
EIF3L eukaryotic translation initiation factor 3, subunit L 1.85339
NISCH nischarin 1.85315
TRIM8 tripartite motif containing 8 1.84842
MTDH metadherin 1.84712
C3 complement component 3 1.84252
COL6A3 collagen, type VI, alpha 3 1.84218
CDK4 cyclin-dependent kinase 4 1.83712
SKP1 S-phase kinase-associated protein 1 1.83429
KIAA0368 KIAA0368 1.83013
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.82344
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 1.82142
GSS glutathione synthetase 1.81608
SEC31A SEC31 homolog A (S. cerevisiae) 1.81448
FAM134A family with sequence similarity 134, member A 1.81314
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 1.81216
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.81206
IFITM1 interferon induced transmembrane protein 1 1.80554
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 1.80425
MAML1 mastermind-like 1 (Drosophila) 1.80376
HDAC1 histone deacetylase 1 1.79524
UQCRC2 ubiquinol-cytochrome c reductase core protein II 1.79024
TXN2 thioredoxin 2 1.78926
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 1.78869
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.78828
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 1.78605
YME1L1 YME1-like 1 ATPase 1.78486
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.78336
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 1.78017
UBXN2A UBX domain protein 2A 1.77929
TEX2 testis expressed 2 1.77919
GREM1 gremlin 1, DAN family BMP antagonist 1.77895
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 1.77765
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 1.7717
NUAK1 NUAK family, SNF1-like kinase, 1 1.76891
ATG13 autophagy related 13 1.76761
RPLP0 ribosomal protein, large, P0 1.76601
CNPPD1 cyclin Pas1/PHO80 domain containing 1 1.76144
DHCR24 24-dehydrocholesterol reductase 1.76013
PSME4 proteasome (prosome, macropain) activator subunit 4 1.75947
WDTC1 WD and tetratricopeptide repeats 1 1.75912
HSPA1A heat shock 70kDa protein 1A 1.75555
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 1.75485
C14ORF2 chromosome 14 open reading frame 2 1.752
RPL22 ribosomal protein L22 1.75075
UBR2 ubiquitin protein ligase E3 component n-recognin 2 1.74974
CRELD2 cysteine-rich with EGF-like domains 2 1.74721
ATG2A autophagy related 2A 1.74509
SMYD3 SET and MYND domain containing 3 1.74491
RPN1 ribophorin I 1.74484
PROS1 protein S (alpha) 1.74367
MXRA5 matrix-remodelling associated 5 1.73537
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.73147
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.72787
FGFR1 fibroblast growth factor receptor 1 1.72658
PA2G4 proliferation-associated 2G4, 38kDa 1.72351
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 1.72234
WDR45 WD repeat domain 45 1.72222
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.7187
CTSK cathepsin K 1.71382
ZCCHC24 zinc finger, CCHC domain containing 24 1.71121
PDIA6 protein disulfide isomerase family A, member 6 1.70727
BRD3 bromodomain containing 3 1.70486
PDIA5 protein disulfide isomerase family A, member 5 1.70348
MAN1C1 mannosidase, alpha, class 1C, member 1 1.69757
PDIA3 protein disulfide isomerase family A, member 3 1.69317
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.69214
C7 complement component 7 1.69008
TTC19 tetratricopeptide repeat domain 19 1.68572
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.68337
TMEM176A transmembrane protein 176A 1.67931
PPIF peptidylprolyl isomerase F 1.67487
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.67334
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 1.6706
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 1.67042
RNF114 ring finger protein 114 1.66947
C4ORF27 chromosome 4 open reading frame 27 1.66813
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.66685
ERLIN2 ER lipid raft associated 2 1.66469
MAP4 microtubule-associated protein 4 1.66406
PRR15L proline rich 15-like 1.66198
RFK riboflavin kinase 1.65553
HPN hepsin 1.65144
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 1.64695
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.64395
MORF4L1 mortality factor 4 like 1 1.64229
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 1.64055
CRTC3 CREB regulated transcription coactivator 3 1.63943
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 1.63875
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.63855
EIF3I eukaryotic translation initiation factor 3, subunit I 1.63018
ACTN1 actinin, alpha 1 1.62786
LRP10 low density lipoprotein receptor-related protein 10 1.62486
CSF3R colony stimulating factor 3 receptor (granulocyte) 1.62237
AGR2 anterior gradient 2 1.62185
MYO9B myosin IXB 1.62005
TCP1 t-complex 1 1.61663
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 1.61503
TAGLN transgelin 1.61365
ZSCAN4 zinc finger and SCAN domain containing 4 1.61031
CD63 CD63 molecule 1.60993
CACYBP calcyclin binding protein 1.60521
CRTAC1 cartilage acidic protein 1 1.604
C1RL complement component 1, r subcomponent-like 1.59992
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 1.59871
FAM45A family with sequence similarity 45, member A 1.59777
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.5952
TSPAN3 tetraspanin 3 1.59255
LRRC47 leucine rich repeat containing 47 1.59168
HSPA8 heat shock 70kDa protein 8 1.58756
CRYM crystallin, mu 1.58601
CTBP1 C-terminal binding protein 1 1.58505
MCAM melanoma cell adhesion molecule 1.585
PRDX6 peroxiredoxin 6 1.58182
ISLR immunoglobulin superfamily containing leucine-rich repeat 1.5811
HTRA1 HtrA serine peptidase 1 1.58095
MAL mal, T-cell differentiation protein 1.5774
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 1.57578
PHB2 prohibitin 2 1.57486
FLNB filamin B, beta 1.57012
PTK7 protein tyrosine kinase 7 (inactive) 1.57009
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.56934
GGCX gamma-glutamyl carboxylase 1.56885
PKNOX2 PBX/knotted 1 homeobox 2 1.56553
TCF4 transcription factor 4 1.56547
CDK13 cyclin-dependent kinase 13 1.56347
KCTD12 potassium channel tetramerization domain containing 12 1.56171
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 1.56098
RPL37 ribosomal protein L37 1.56047
SNX11 sorting nexin 11 1.56031
TUBA4A tubulin, alpha 4a 1.55733
FBXL7 F-box and leucine-rich repeat protein 7 1.55702
MOXD1 monooxygenase, DBH-like 1 1.55442
CKB creatine kinase, brain 1.55397
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.55217
DLG3 discs, large homolog 3 (Drosophila) 1.55081
EDF1 endothelial differentiation-related factor 1 1.54936
SYNPO synaptopodin 1.54913
C10ORF10 chromosome 10 open reading frame 10 1.54423
SEC61B Sec61 beta subunit 1.5407
DUT deoxyuridine triphosphatase 1.5375
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.52964
STK19 serine/threonine kinase 19 1.52959
FBLN5 fibulin 5 1.52717
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 1.52144
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.51986
PRCP prolylcarboxypeptidase (angiotensinase C) 1.51978
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 1.51712
PNRC2 proline-rich nuclear receptor coactivator 2 1.51444
MYO1D myosin ID 1.51297
PVRIG poliovirus receptor related immunoglobulin domain containing 1.51155
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.51098
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.51073
TMEM176B transmembrane protein 176B 1.5085
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 1.50821
LDHB lactate dehydrogenase B 1.50747
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.50268
CD24 CD24 molecule 1.50207
RPS9 ribosomal protein S9 1.50184
TSPAN6 tetraspanin 6 1.50167
UFC1 ubiquitin-fold modifier conjugating enzyme 1 1.50065
CD302 CD302 molecule 1.49628
HLTF helicase-like transcription factor 1.49479
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.4943
MADD MAP-kinase activating death domain 1.49414
FAM53B family with sequence similarity 53, member B 1.49184
MLX MLX, MAX dimerization protein 1.49057
PAM peptidylglycine alpha-amidating monooxygenase 1.4895
CHPT1 choline phosphotransferase 1 1.48158
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 1.47582
CXCL12 chemokine (C-X-C motif) ligand 12 1.47569
RAB17 RAB17, member RAS oncogene family 1.47472
H1F0 H1 histone family, member 0 1.47455
TBXA2R thromboxane A2 receptor 1.47371
CNPY2 canopy FGF signaling regulator 2 1.47225
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.47046
MED13 mediator complex subunit 13 1.46977
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.46974
CBX1 chromobox homolog 1 1.46833
PFN2 profilin 2 1.46791
PLAU plasminogen activator, urokinase 1.46518
MID1 midline 1 1.46471
FAM193B family with sequence similarity 193, member B 1.46465
CLK2 CDC-like kinase 2 1.46424
H2AFZ H2A histone family, member Z 1.46205
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 1.46074
TSC2 tuberous sclerosis 2 1.46071
MED12 mediator complex subunit 12 1.45655
AHCY adenosylhomocysteinase 1.45401
MYLK myosin light chain kinase 1.45248
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 1.45212
ACO1 aconitase 1, soluble 1.44858
CALR calreticulin 1.44806
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 1.44781
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.44589
TLR5 toll-like receptor 5 1.4444
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 1.44386
CRELD1 cysteine-rich with EGF-like domains 1 1.44197
MOGS mannosyl-oligosaccharide glucosidase 1.44059
GYG1 glycogenin 1 1.44058
SRPK1 SRSF protein kinase 1 1.43914
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 1.43656
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.43617
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.43535

decreased expression

Symbol Name Standardized Value
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -2.97231
GON4L gon-4-like (C. elegans) -2.84272
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -2.72899
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.72072
MX2 MX dynamin-like GTPase 2 -2.6171
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.5744
GNAS GNAS complex locus -2.56682
HECA headcase homolog (Drosophila) -2.54721
DCTN6 dynactin 6 -2.48669
MFN2 mitofusin 2 -2.48009
TMEM248 transmembrane protein 248 -2.43998
ADAM22 ADAM metallopeptidase domain 22 -2.42922
ACOT13 acyl-CoA thioesterase 13 -2.38842
MGST3 microsomal glutathione S-transferase 3 -2.376
PRDX1 peroxiredoxin 1 -2.36418
PARL presenilin associated, rhomboid-like -2.30417
APH1B APH1B gamma secretase subunit -2.29494
STX8 syntaxin 8 -2.27806
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -2.25571
RPL41 ribosomal protein L41 -2.24774
FLII flightless I homolog (Drosophila) -2.24248
ANXA2 annexin A2 -2.23028
SH3GLB1 SH3-domain GRB2-like endophilin B1 -2.22274
CIRBP cold inducible RNA binding protein -2.19971
JTB jumping translocation breakpoint -2.18778
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -2.18269
LSM12 LSM12 homolog (S. cerevisiae) -2.16131
CSNK1E casein kinase 1, epsilon -2.15092
LOC139061 plasmolipin pseudogene -2.14798
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -2.14062
HEXB hexosaminidase B (beta polypeptide) -2.13119
JRK Jrk homolog (mouse) -2.13115
MSL1 male-specific lethal 1 homolog (Drosophila) -2.11648
KRT33A keratin 33A, type I -2.10436
UBE2Z ubiquitin-conjugating enzyme E2Z -2.07997
OXSR1 oxidative stress responsive 1 -2.0796
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -2.07601
ASXL2 additional sex combs like transcriptional regulator 2 -2.07043
S100A10 S100 calcium binding protein A10 -2.06869
PHF10 PHD finger protein 10 -2.04834
LHFPL2 lipoma HMGIC fusion partner-like 2 -2.0157
MYO5C myosin VC -2.01122
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.00871
TRIOBP TRIO and F-actin binding protein -1.99408
HELZ helicase with zinc finger -1.99095
GLA galactosidase, alpha -1.98992
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) -1.97863
ATF4 activating transcription factor 4 -1.97476
STRADA STE20-related kinase adaptor alpha -1.971
OPN3 opsin 3 -1.96625
ACVR1 activin A receptor, type I -1.95216
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) -1.94959
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -1.94446
FGL1 fibrinogen-like 1 -1.93752
ANXA1 annexin A1 -1.93159
FXYD3 FXYD domain containing ion transport regulator 3 -1.90974
TERF2IP telomeric repeat binding factor 2, interacting protein -1.90072
C7ORF49 chromosome 7 open reading frame 49 -1.88926
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -1.88103
TDRD7 tudor domain containing 7 -1.87712
OR3A1 olfactory receptor, family 3, subfamily A, member 1 -1.867
LPXN leupaxin -1.86589
CIB1 calcium and integrin binding 1 (calmyrin) -1.86566
ADSL adenylosuccinate lyase -1.85708
SH2B1 SH2B adaptor protein 1 -1.84497
TAL1 T-cell acute lymphocytic leukemia 1 -1.84394
ACP1 acid phosphatase 1, soluble -1.8423
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -1.83906
FABP4 fatty acid binding protein 4, adipocyte -1.82789
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) -1.82091
TMUB2 transmembrane and ubiquitin-like domain containing 2 -1.81581
PTTG1IP pituitary tumor-transforming 1 interacting protein -1.8142
CSNK2B casein kinase 2, beta polypeptide -1.81363
ADPGK ADP-dependent glucokinase -1.80992
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -1.80823
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.80778
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -1.80281
NECAP2 NECAP endocytosis associated 2 -1.80177
PPP1R10 protein phosphatase 1, regulatory subunit 10 -1.79345
FBRS fibrosin -1.79271
ZNF7 zinc finger protein 7 -1.79168
STARD13 StAR-related lipid transfer (START) domain containing 13 -1.79114
GDF15 growth differentiation factor 15 -1.76925
NOP16 NOP16 nucleolar protein -1.76755
SDF4 stromal cell derived factor 4 -1.75772
CDC16 cell division cycle 16 -1.75579
VIM vimentin -1.75547
HMOX1 heme oxygenase 1 -1.7554
CAPRIN2 caprin family member 2 -1.75224
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.75173
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -1.74941
ANXA3 annexin A3 -1.74786
SUN2 Sad1 and UNC84 domain containing 2 -1.7467
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -1.7464
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -1.7444
ZC3H7A zinc finger CCCH-type containing 7A -1.7407
HYI hydroxypyruvate isomerase (putative) -1.7403
TM2D1 TM2 domain containing 1 -1.73757
IRF8 interferon regulatory factor 8 -1.73422
SLC31A2 solute carrier family 31 (copper transporter), member 2 -1.73359
TUBB6 tubulin, beta 6 class V -1.73184
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -1.73155
SMCP sperm mitochondria-associated cysteine-rich protein -1.72149
ANKRD17 ankyrin repeat domain 17 -1.71868
WDR26 WD repeat domain 26 -1.71615
LINC00667 long intergenic non-protein coding RNA 667 -1.71465
FAM184A family with sequence similarity 184, member A -1.71336
BTNL3 butyrophilin-like 3 -1.71249
THEMIS2 thymocyte selection associated family member 2 -1.71101
RPH3AL rabphilin 3A-like (without C2 domains) -1.709
C18ORF8 chromosome 18 open reading frame 8 -1.70407
HSBP1 heat shock factor binding protein 1 -1.69454
BRD9 bromodomain containing 9 -1.69311
AMT aminomethyltransferase -1.6917
TREM1 triggering receptor expressed on myeloid cells 1 -1.68771
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -1.68721
SAP130 Sin3A-associated protein, 130kDa -1.68566
PRDM8 PR domain containing 8 -1.6856
LGALS3 lectin, galactoside-binding, soluble, 3 -1.68446
CSF1 colony stimulating factor 1 (macrophage) -1.68207
PCBP1 poly(rC) binding protein 1 -1.67857
LGALS14 lectin, galactoside-binding, soluble, 14 -1.67856
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -1.67601
RECQL4 RecQ protein-like 4 -1.67015
GALT galactose-1-phosphate uridylyltransferase -1.66999
CTSO cathepsin O -1.66868
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -1.6617
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -1.66089
HPCAL1 hippocalcin-like 1 -1.65943
KYNU kynureninase -1.65833
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) -1.65618
TGIF1 TGFB-induced factor homeobox 1 -1.65457
ADGRE5 adhesion G protein-coupled receptor E5 -1.65057
ADCK2 aarF domain containing kinase 2 -1.64707
COX17 COX17 cytochrome c oxidase copper chaperone -1.64489
BCL2L2 BCL2-like 2 -1.64358
FAM189A2 family with sequence similarity 189, member A2 -1.63861
TRIO trio Rho guanine nucleotide exchange factor -1.63694
GGPS1 geranylgeranyl diphosphate synthase 1 -1.63329
UBA7 ubiquitin-like modifier activating enzyme 7 -1.63149
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -1.63076
DSCR3 Down syndrome critical region 3 -1.62947
AGTR1 angiotensin II receptor, type 1 -1.62569
ZNF263 zinc finger protein 263 -1.62407
CDHR5 cadherin-related family member 5 -1.62071
BRD1 bromodomain containing 1 -1.61238
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -1.60692
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -1.6041
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -1.60098
DOLPP1 dolichyldiphosphatase 1 -1.59582
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 -1.59547
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) -1.59535
MTMR14 myotubularin related protein 14 -1.59327
DIAPH1 diaphanous-related formin 1 -1.59219
IRF7 interferon regulatory factor 7 -1.58824
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -1.58793
RLF rearranged L-myc fusion -1.58784
CAV1 caveolin 1, caveolae protein, 22kDa -1.5856
APMAP adipocyte plasma membrane associated protein -1.58456
FBXO28 F-box protein 28 -1.58319
ADGRE1 adhesion G protein-coupled receptor E1 -1.58282
BTG3 BTG family, member 3 -1.58255
ADCY3 adenylate cyclase 3 -1.5824
NUP85 nucleoporin 85kDa -1.58186
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -1.5801
GLT8D1 glycosyltransferase 8 domain containing 1 -1.57848
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -1.57725
ITPK1 inositol-tetrakisphosphate 1-kinase -1.57658
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 -1.57562
AMD1 adenosylmethionine decarboxylase 1 -1.57062
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 -1.56954
DENND3 DENN/MADD domain containing 3 -1.56915
ETF1 eukaryotic translation termination factor 1 -1.56753
EIF5 eukaryotic translation initiation factor 5 -1.56502
LRRC14 leucine rich repeat containing 14 -1.56039
IVNS1ABP influenza virus NS1A binding protein -1.55953
MGST2 microsomal glutathione S-transferase 2 -1.55824
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -1.55476
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 -1.55364
MUS81 MUS81 structure-specific endonuclease subunit -1.55322
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -1.55199
PANK4 pantothenate kinase 4 -1.548
TEX264 testis expressed 264 -1.54794
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -1.53796
MINK1 misshapen-like kinase 1 -1.53632
DAPK1 death-associated protein kinase 1 -1.53297
TAC3 tachykinin 3 -1.53145
CNTNAP1 contactin associated protein 1 -1.52971
RGS12 regulator of G-protein signaling 12 -1.52053
BTK Bruton agammaglobulinemia tyrosine kinase -1.51908
FAM53C family with sequence similarity 53, member C -1.51756
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -1.51732
HCFC1 host cell factor C1 -1.5158
MUC3B mucin 3B, cell surface associated -1.5157
UIMC1 ubiquitin interaction motif containing 1 -1.51507
MRPS22 mitochondrial ribosomal protein S22 -1.5149
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -1.51114
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -1.51035
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -1.50391
FSHR follicle stimulating hormone receptor -1.50326
TMSB10 thymosin beta 10 -1.50025
CCDC28A coiled-coil domain containing 28A -1.49939
RPL23A ribosomal protein L23a -1.49886
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.49652
ADGRG6 adhesion G protein-coupled receptor G6 -1.49526
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -1.49294
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -1.49223
COPS3 COP9 signalosome subunit 3 -1.49141
SNW1 SNW domain containing 1 -1.49107
WNT6 wingless-type MMTV integration site family, member 6 -1.4905
PDE4DIP phosphodiesterase 4D interacting protein -1.48744
GRHPR glyoxylate reductase/hydroxypyruvate reductase -1.48731
SPAG7 sperm associated antigen 7 -1.48615
SF3A3 splicing factor 3a, subunit 3, 60kDa -1.48575
SYNGR2 synaptogyrin 2 -1.48484
JAK1 Janus kinase 1 -1.4842
BLVRA biliverdin reductase A -1.48236
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -1.48065
CSNK1A1 casein kinase 1, alpha 1 -1.47809
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -1.47541
MPL MPL proto-oncogene, thrombopoietin receptor -1.47531
GALC galactosylceramidase -1.47525
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -1.47373
RECQL5 RecQ protein-like 5 -1.47349
CIT citron rho-interacting serine/threonine kinase -1.47269
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -1.47231
CERK ceramide kinase -1.4698
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -1.46905
APH1A APH1A gamma secretase subunit -1.46863
SPRED2 sprouty-related, EVH1 domain containing 2 -1.46318
ECH1 enoyl CoA hydratase 1, peroxisomal -1.46297
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -1.46149
EFHD2 EF-hand domain family, member D2 -1.46034
LMBRD1 LMBR1 domain containing 1 -1.45893
UBL5 ubiquitin-like 5 -1.4581
LAMA2 laminin, alpha 2 -1.45777
GSN gelsolin -1.45558
CARD10 caspase recruitment domain family, member 10 -1.45511
BCKDK branched chain ketoacid dehydrogenase kinase -1.45489
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -1.45396
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -1.45369
S100A4 S100 calcium binding protein A4 -1.45327
ENSA endosulfine alpha -1.45264
TRAPPC3 trafficking protein particle complex 3 -1.45188
PRKCA protein kinase C, alpha -1.44611
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -1.44346
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -1.44324
AKAP8 A kinase (PRKA) anchor protein 8 -1.44145
RBMX RNA binding motif protein, X-linked -1.44044
ARID1A AT rich interactive domain 1A (SWI-like) -1.43919
FAM65A family with sequence similarity 65, member A -1.43781
ABHD10 abhydrolase domain containing 10 -1.4376
ZNF428 zinc finger protein 428 -1.43547
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene -1.43512
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -1.43488
DIAPH2 diaphanous-related formin 2 -1.43285
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -1.43085
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.4272
NEK3 NIMA-related kinase 3 -1.42708
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -1.42355
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -1.4225
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -1.4224
LARP7 La ribonucleoprotein domain family, member 7 -1.42105
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -1.42054
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -1.41928
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -1.41083
HIF3A hypoxia inducible factor 3, alpha subunit -1.41074
FANCI Fanconi anemia, complementation group I -1.40908
SYNE1 spectrin repeat containing, nuclear envelope 1 -1.40547
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -1.40525
TBP TATA box binding protein -1.40289
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -1.39799
TFRC transferrin receptor -1.39747
ZC3H14 zinc finger CCCH-type containing 14 -1.39687
RAB11FIP1 RAB11 family interacting protein 1 (class I) -1.39629
USP25 ubiquitin specific peptidase 25 -1.39544
RANBP1 RAN binding protein 1 -1.39493
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -1.39261
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -1.39115
GMFG glia maturation factor, gamma -1.3903
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -1.38927
ACP2 acid phosphatase 2, lysosomal -1.38851
GPR132 G protein-coupled receptor 132 -1.38843
DCTN3 dynactin 3 (p22) -1.38763
CD53 CD53 molecule -1.38538
ZNF672 zinc finger protein 672 -1.38438
FOXF1 forkhead box F1 -1.38369
MBD2 methyl-CpG binding domain protein 2 -1.38359
SART1 squamous cell carcinoma antigen recognized by T cells -1.38356
U2AF1 U2 small nuclear RNA auxiliary factor 1 -1.38258
CREBZF CREB/ATF bZIP transcription factor -1.38178
TAOK2 TAO kinase 2 -1.38109
RALYL RALY RNA binding protein-like -1.37794
KIAA0141 KIAA0141 -1.37704
SGCE sarcoglycan, epsilon -1.37288
MMP19 matrix metallopeptidase 19 -1.37232
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -1.37132
TMEM74B transmembrane protein 74B -1.37039
COG2 component of oligomeric golgi complex 2 -1.37038
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 -1.36935