Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

427 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL4 arylacetamide deacetylase-like 4
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABLIM1 actin binding LIM protein 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACBD5 acyl-CoA binding domain containing 5
ACOX2 acyl-CoA oxidase 2, branched chain
ACVR1C activin A receptor, type IC
ADAMTSL3 ADAMTS-like 3
ADCY8 adenylate cyclase 8 (brain)
ADD3 adducin 3 (gamma)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AHCYL1 adenosylhomocysteinase-like 1
AHNAK AHNAK nucleoprotein
AKAP5 A kinase (PRKA) anchor protein 5
ALAD aminolevulinate dehydratase
AMOT angiomotin
ANGPTL3 angiopoietin-like 3
ANK2 ankyrin 2, neuronal
ANKDD1A ankyrin repeat and death domain containing 1A
ANKRD9 ankyrin repeat domain 9
ANO3 anoctamin 3
ANTXR1 anthrax toxin receptor 1
ANXA8L1 annexin A8-like 1
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGAP21 Rho GTPase activating protein 21
ARHGAP42 Rho GTPase activating protein 42
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARSG arylsulfatase G
ARSH arylsulfatase family, member H
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASCL3 achaete-scute family bHLH transcription factor 3
ATOH7 atonal homolog 7 (Drosophila)
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide
AZIN1 antizyme inhibitor 1
B3GAT2 beta-1,3-glucuronyltransferase 2
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BBS1 Bardet-Biedl syndrome 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP10 bone morphogenetic protein 10
BSPH1 binder of sperm protein homolog 1
BTBD3 BTB (POZ) domain containing 3
C10ORF131 chromosome 10 open reading frame 131
C10ORF91 chromosome 10 open reading frame 91
C22ORF24 chromosome 22 open reading frame 24
C2ORF88 chromosome 2 open reading frame 88
C5ORF52 chromosome 5 open reading frame 52
C6ORF10 chromosome 6 open reading frame 10
C7ORF66 chromosome 7 open reading frame 66
C7ORF72 chromosome 7 open reading frame 72
C8ORF33 chromosome 8 open reading frame 33
CACHD1 cache domain containing 1
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAPN1 calpain 1, (mu/I) large subunit
CARD18 caspase recruitment domain family, member 18
CASC4 cancer susceptibility candidate 4
CCDC163P coiled-coil domain containing 163, pseudogene
CCDC6 coiled-coil domain containing 6
CCDC85A coiled-coil domain containing 85A
CCIN calicin
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CD38 CD38 molecule
CEACAM22P carcinoembryonic antigen-related cell adhesion molecule 22, pseudogene
CERS6 ceramide synthase 6
CH25H cholesterol 25-hydroxylase
CHD1L chromodomain helicase DNA binding protein 1-like
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
CNTN5 contactin 5
COL10A1 collagen, type X, alpha 1
COLCA2 colorectal cancer associated 2
CRYGN crystallin, gamma N
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTNND2 catenin (cadherin-associated protein), delta 2
CTSH cathepsin H
CUL5 cullin 5
CXORF58 chromosome X open reading frame 58
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DAAM2 dishevelled associated activator of morphogenesis 2
DCK deoxycytidine kinase
DCLK1 doublecortin-like kinase 1
DCLK3 doublecortin-like kinase 3
DCSTAMP dendrocyte expressed seven transmembrane protein
DDR2 discoidin domain receptor tyrosine kinase 2
DEFB132 defensin, beta 132
DGKI diacylglycerol kinase, iota
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNAJC25-GNG10 DNAJC25-GNG10 readthrough
DNAL1 dynein, axonemal, light chain 1
DOCK7 dedicator of cytokinesis 7
DOK6 docking protein 6
DPPA5 developmental pluripotency associated 5
DPY19L3 dpy-19-like 3 (C. elegans)
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EBAG9 estrogen receptor binding site associated, antigen, 9
EDNRB endothelin receptor type B
EGR3 early growth response 3
ELSPBP1 epididymal sperm binding protein 1
EMC2 ER membrane protein complex subunit 2
EML6 echinoderm microtubule associated protein like 6
ENKUR enkurin, TRPC channel interacting protein
EPCAM epithelial cell adhesion molecule
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERBB2IP erbb2 interacting protein
ETNPPL ethanolamine-phosphate phospho-lyase
FAM167A family with sequence similarity 167, member A
FAM168A family with sequence similarity 168, member A
FAM171A1 family with sequence similarity 171, member A1
FAM217A family with sequence similarity 217, member A
FAM227B family with sequence similarity 227, member B
FAM69A family with sequence similarity 69, member A
FAM83H family with sequence similarity 83, member H
FAM90A7P putative protein FAM90A7
FAM92A1 family with sequence similarity 92, member A1
FAM92A1P2 family with sequence similarity 92, member A3
FCAR Fc fragment of IgA receptor
FER fer (fps/fes related) tyrosine kinase
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF4 fibroblast growth factor 4
FMN2 formin 2
FNBP1L formin binding protein 1-like
FRG2 FSHD region gene 2
FSD1L fibronectin type III and SPRY domain containing 1-like
FSHB follicle stimulating hormone, beta polypeptide
FTO fat mass and obesity associated
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GATSL2 GATS protein-like 2
GBX2 gastrulation brain homeobox 2
GCM2 glial cells missing homolog 2 (Drosophila)
GDF11 growth differentiation factor 11
GFRA4 GDNF family receptor alpha 4
GHR growth hormone receptor
GHSR growth hormone secretagogue receptor
GINS3 GINS complex subunit 3 (Psf3 homolog)
GJA1 gap junction protein, alpha 1, 43kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GJB7 gap junction protein, beta 7, 25kDa
GLT6D1 glycosyltransferase 6 domain containing 1
GMFB glia maturation factor, beta
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA8IP golgin A8 family, member I, pseudogene
GOLIM4 golgi integral membrane protein 4
GOLM1 golgi membrane protein 1
GPR25 G protein-coupled receptor 25
GRXCR1 glutaredoxin, cysteine rich 1
GSDMC gasdermin C
GSTM3 glutathione S-transferase mu 3 (brain)
GTF2H5 general transcription factor IIH, polypeptide 5
GUCA2B guanylate cyclase activator 2B (uroguanylin)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HADH hydroxyacyl-CoA dehydrogenase
HEPACAM hepatic and glial cell adhesion molecule
HES1 hes family bHLH transcription factor 1
HIST1H2BI histone cluster 1, H2bi
HIST1H4L histone cluster 1, H4l
HLTF helicase-like transcription factor
HPSE2 heparanase 2 (inactive)
HSDL2 hydroxysteroid dehydrogenase like 2
IDI1 isopentenyl-diphosphate delta isomerase 1
IDI2-AS1 IDI2 antisense RNA 1
IGFL4 IGF-like family member 4
IL17RD interleukin 17 receptor D
IL9 interleukin 9
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCJ IQ motif containing J
ITGA6 integrin, alpha 6
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITSN1 intersectin 1 (SH3 domain protein)
JAM2 junctional adhesion molecule 2
KATNAL1 katanin p60 subunit A-like 1
KBTBD3 kelch repeat and BTB (POZ) domain containing 3
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNU1 potassium channel, subfamily U, member 1
KHDC1L KH homology domain containing 1-like
KLHL5 kelch-like family member 5
KLK7 kallikrein-related peptidase 7
KLK8 kallikrein-related peptidase 8
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRT25 keratin 25, type I
KRT33A keratin 33A, type I
KRT78 keratin 78, type II
KRT83 keratin 83, type II
KRTAP1-1 keratin associated protein 1-1
KRTAP11-1 keratin associated protein 11-1
LIMCH1 LIM and calponin homology domains 1
LIMK2 LIM domain kinase 2
LINC00032 long intergenic non-protein coding RNA 32
LINC00521 long intergenic non-protein coding RNA 521
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC100130987 uncharacterized LOC100130987
LOC200726 hCG1657980
LOC645752 golgin A6 family, member A pseudogene
LOC653653 adaptor-related protein complex 1, sigma 2 subunit pseudogene
LOC728392 uncharacterized LOC728392
LOC728554 THO complex 3 pseudogene
LPIN1 lipin 1
LRMP lymphoid-restricted membrane protein
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LRTM1 leucine-rich repeats and transmembrane domains 1
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene)
MAP4 microtubule-associated protein 4
MAPK1 mitogen-activated protein kinase 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MBOAT4 membrane bound O-acyltransferase domain containing 4
MC4R melanocortin 4 receptor
MCCD1 mitochondrial coiled-coil domain 1
MINK1 misshapen-like kinase 1
MLNR motilin receptor
MOGAT2 monoacylglycerol O-acyltransferase 2
MPRIP myosin phosphatase Rho interacting protein
MROH6 maestro heat-like repeat family member 6
MRVI1 murine retrovirus integration site 1 homolog
MSRB3 methionine sulfoxide reductase B3
MUC7 mucin 7, secreted
MYH15 myosin, heavy chain 15
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
MYL10 myosin, light chain 10, regulatory
NADK2 NAD kinase 2, mitochondrial
NEK7 NIMA-related kinase 7
NEUROG3 neurogenin 3
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NLRP10 NLR family, pyrin domain containing 10
NLRP3 NLR family, pyrin domain containing 3
NMT2 N-myristoyltransferase 2
NPY4R neuropeptide Y receptor Y4
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRBP2 nuclear receptor binding protein 2
NRG3 neuregulin 3
NRROS negative regulator of reactive oxygen species
NT5DC3 5'-nucleotidase domain containing 3
NUDCD1 NudC domain containing 1
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
NXNL2 nucleoredoxin-like 2
OGFRL1 opioid growth factor receptor-like 1
OPRM1 opioid receptor, mu 1
OPTN optineurin
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2Z1 olfactory receptor, family 2, subfamily Z, member 1
OR51Q1 olfactory receptor, family 51, subfamily Q, member 1 (gene/pseudogene)
OR52E4 olfactory receptor, family 52, subfamily E, member 4
OR52N5 olfactory receptor, family 52, subfamily N, member 5
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2
OR5AK2 olfactory receptor, family 5, subfamily AK, member 2
OR5K1 olfactory receptor, family 5, subfamily K, member 1
OR5V1 olfactory receptor, family 5, subfamily V, member 1
OR6C65 olfactory receptor, family 6, subfamily C, member 65
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTOF otoferlin
OTUD1 OTU deubiquitinase 1
PARD3B par-3 family cell polarity regulator beta
PATE1 prostate and testis expressed 1
PC pyruvate carboxylase
PCDHGB1 protocadherin gamma subfamily B, 1
PDE4DIP phosphodiesterase 4D interacting protein
PHEX phosphate regulating endopeptidase homolog, X-linked
PITRM1 pitrilysin metallopeptidase 1
PLA2G12A phospholipase A2, group XIIA
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCD3 phospholipase C, delta 3
PLEC plectin
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLSCR4 phospholipid scramblase 4
PMP2 peripheral myelin protein 2
PPBPP2 pro-platelet basic protein pseudogene 2
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PRAP1 proline-rich acidic protein 1
PRDM5 PR domain containing 5
PRKCG protein kinase C, gamma
PRSS21 protease, serine, 21 (testisin)
PRSS37 protease, serine, 37
PRTFDC1 phosphoribosyl transferase domain containing 1
PSG5 pregnancy specific beta-1-glycoprotein 5
PTCH2 patched 2
PTCHD1 patched domain containing 1
RAB23 RAB23, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RAVER2 ribonucleoprotein, PTB-binding 2
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RDX radixin
REC114 REC114 meiotic recombination protein
RESP18 regulated endocrine-specific protein 18
RET ret proto-oncogene
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGS1 regulator of G-protein signaling 1
RHPN1 rhophilin, Rho GTPase binding protein 1
RIPPLY1 ripply transcriptional repressor 1
RMDN1 regulator of microtubule dynamics 1
RNF115 ring finger protein 115
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RSG1 REM2 and RAB-like small GTPase 1
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RTP3 receptor (chemosensory) transporter protein 3
RYR1 ryanodine receptor 1 (skeletal)
SAG S-antigen; retina and pineal gland (arrestin)
SC5D sterol-C5-desaturase
SCCPDH saccharopine dehydrogenase (putative)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG3 secretogranin III
SCN4B sodium channel, voltage gated, type IV beta subunit
SCRIB scribbled planar cell polarity protein
SEC1P secretory blood group 1, pseudogene
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SERTM1 serine-rich and transmembrane domain containing 1
SH3BP2 SH3-domain binding protein 2
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMIM21 small integral membrane protein 21
SNORA18 small nucleolar RNA, H/ACA box 18
SNORA81 small nucleolar RNA, H/ACA box 81
SNORA9 small nucleolar RNA, H/ACA box 9
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNX7 sorting nexin 7
SOAT2 sterol O-acyltransferase 2
SORBS1 sorbin and SH3 domain containing 1
SORD sorbitol dehydrogenase
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPAG11B sperm associated antigen 11B
SPANXB1 SPANX family, member B1
SPANXC SPANX family, member C
SPIN1 spindlin 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SPX spexin hormone
ST7-OT4 ST7 overlapping transcript 4
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STH saitohin
STK3 serine/threonine kinase 3
STOX1 storkhead box 1
STX11 syntaxin 11
STX17 syntaxin 17
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SUMO3 small ubiquitin-like modifier 3
SUMO4 small ubiquitin-like modifier 4
SYNM synemin, intermediate filament protein
SYTL1 synaptotagmin-like 1
SYTL5 synaptotagmin-like 5
TAAR6 trace amine associated receptor 6
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D21 TBC1 domain family, member 21
TBCEL tubulin folding cofactor E-like
TDO2 tryptophan 2,3-dioxygenase
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TESK2 testis-specific kinase 2
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
TGFBR3 transforming growth factor, beta receptor III
TGM3 transglutaminase 3
TGM6 transglutaminase 6
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TJP2 tight junction protein 2
TLR4 toll-like receptor 4
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TMEM215 transmembrane protein 215
TMEM236 transmembrane protein 236
TMEM47 transmembrane protein 47
TMEM56 transmembrane protein 56
TMPRSS11A transmembrane protease, serine 11A
TMPRSS6 transmembrane protease, serine 6
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TPRX1 tetra-peptide repeat homeobox 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM43 tripartite motif containing 43
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPS1 trichorhinophalangeal syndrome I
TTPA tocopherol (alpha) transfer protein
TUBB7P tubulin, beta 7, pseudogene
TWSG1 twisted gastrulation BMP signaling modulator 1
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10
ULK4P3 ULK4 pseudogene 3
UNC13B unc-13 homolog B (C. elegans)
USP46 ubiquitin specific peptidase 46
USP50 ubiquitin specific peptidase 50
UTRN utrophin
UTS2B urotensin 2B
VENTX VENT homeobox
VN1R1 vomeronasal 1 receptor 1
WDR11 WD repeat domain 11
WDR31 WD repeat domain 31
WDR49 WD repeat domain 49
WNT8A wingless-type MMTV integration site family, member 8A
WWOX WW domain containing oxidoreductase
WWP1 WW domain containing E3 ubiquitin protein ligase 1
YAP1 Yes-associated protein 1
ZBTB25 zinc finger and BTB domain containing 25
ZC3H12C zinc finger CCCH-type containing 12C
ZHX1 zinc fingers and homeoboxes 1
ZMYND11 zinc finger, MYND-type containing 11
ZNF251 zinc finger protein 251
ZNF252P zinc finger protein 252, pseudogene
ZNF483 zinc finger protein 483
ZNF518B zinc finger protein 518B
ZNF641 zinc finger protein 641
ZNF664 zinc finger protein 664
ZNF7 zinc finger protein 7
ZNF703 zinc finger protein 703
ZNF706 zinc finger protein 706
ZNF81 zinc finger protein 81
ZPBP2 zona pellucida binding protein 2
ZSCAN5B zinc finger and SCAN domain containing 5B

low expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ANAPC13 anaphase promoting complex subunit 13
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
DBR1 debranching RNA lariats 1
PBDC1 polysaccharide biosynthesis domain containing 1