Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

395 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABLIM1 actin binding LIM protein 1
ACAA1 acetyl-CoA acyltransferase 1
ACBD5 acyl-CoA binding domain containing 5
ACE2 angiotensin I converting enzyme 2
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACSM5 acyl-CoA synthetase medium-chain family member 5
ACTL9 actin-like 9
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADD1 adducin 1 (alpha)
ADGRF4 adhesion G protein-coupled receptor F4
ADGRG5 adhesion G protein-coupled receptor G5
AHCYL1 adenosylhomocysteinase-like 1
AHCYL2 adenosylhomocysteinase-like 2
AK3 adenylate kinase 3
AKAP13 A kinase (PRKA) anchor protein 13
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANGPT4 angiopoietin 4
ANGPTL1 angiopoietin-like 1
ANKRD28 ankyrin repeat domain 28
ANKRD44 ankyrin repeat domain 44
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
AP1AR adaptor-related protein complex 1 associated regulatory protein
AR androgen receptor
AREG amphiregulin
ARHGAP12 Rho GTPase activating protein 12
ARHGAP27 Rho GTPase activating protein 27
ARHGAP31 Rho GTPase activating protein 31
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL8B ADP-ribosylation factor-like 8B
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASB3 ankyrin repeat and SOCS box containing 3
ATG13 autophagy related 13
ATP13A4 ATPase type 13A4
AZI2 5-azacytidine induced 2
BARD1 BRCA1 associated RING domain 1
BMP10 bone morphogenetic protein 10
BMP15 bone morphogenetic protein 15
BTN3A2 butyrophilin, subfamily 3, member A2
C10ORF120 chromosome 10 open reading frame 120
C11ORF52 chromosome 11 open reading frame 52
C19ORF33 chromosome 19 open reading frame 33
C1ORF162 chromosome 1 open reading frame 162
C20ORF197 chromosome 20 open reading frame 197
C22ORF34 chromosome 22 open reading frame 34
C2ORF57 chromosome 2 open reading frame 57
C4ORF3 chromosome 4 open reading frame 3
C6ORF89 chromosome 6 open reading frame 89
C7ORF73 chromosome 7 open reading frame 73
C9ORF139 chromosome 9 open reading frame 139
CAB39L calcium binding protein 39-like
CACUL1 CDK2-associated, cullin domain 1
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN7 calpain 7
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3
CARD17 caspase recruitment domain family, member 17
CARD6 caspase recruitment domain family, member 6
CBWD1 COBW domain containing 1
CCDC136 coiled-coil domain containing 136
CCDC160 coiled-coil domain containing 160
CCDC178 coiled-coil domain containing 178
CCR2 chemokine (C-C motif) receptor 2
CCR9 chemokine (C-C motif) receptor 9
CD1D CD1d molecule
CD38 CD38 molecule
CD69 CD69 molecule
CDC14A cell division cycle 14A
CDH20 cadherin 20, type 2
CDK19 cyclin-dependent kinase 19
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEMIP cell migration inducing protein, hyaluronan binding
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
CLASP2 cytoplasmic linker associated protein 2
CLEC16A C-type lectin domain family 16, member A
CLIC2 chloride intracellular channel 2
CNTF ciliary neurotrophic factor
CNTN1 contactin 1
CNTN3 contactin 3 (plasmacytoma associated)
COL4A6 collagen, type IV, alpha 6
CRBN cereblon
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSNK1A1L casein kinase 1, alpha 1-like
CSTA cystatin A (stefin A)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTRB1 chymotrypsinogen B1
CTSO cathepsin O
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCAF12 DDB1 and CUL4 associated factor 12
DCP1A decapping mRNA 1A
DDB1 damage-specific DNA binding protein 1, 127kDa
DEFB1 defensin, beta 1
DHFRL1 dihydrofolate reductase-like 1
DHRS4-AS1 DHRS4 antisense RNA 1
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DMD dystrophin
DNASE2B deoxyribonuclease II beta
DNMBP-AS1 DNMBP antisense RNA 1
DOCK11 dedicator of cytokinesis 11
DSPP dentin sialophosphoprotein
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDNRA endothelin receptor type A
EIF1B eukaryotic translation initiation factor 1B
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
ERBB2IP erbb2 interacting protein
EXOC4 exocyst complex component 4
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EYS eyes shut homolog (Drosophila)
F8 coagulation factor VIII, procoagulant component
FAM105A family with sequence similarity 105, member A
FAM136BP family with sequence similarity 136, member B, pseudogene
FAM169A family with sequence similarity 169, member A
FAM180A family with sequence similarity 180, member A
FAM185A family with sequence similarity 185, member A
FAM188A family with sequence similarity 188, member A
FAM188B family with sequence similarity 188, member B
FAM214A family with sequence similarity 214, member A
FAM214B family with sequence similarity 214, member B
FAM26F family with sequence similarity 26, member F
FGL2 fibrinogen-like 2
FLT3 fms-related tyrosine kinase 3
FMO5 flavin containing monooxygenase 5
FRG2C FSHD region gene 2 family, member C
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALC galactosylceramidase
GFRA2 GDNF family receptor alpha 2
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene
GJA3 gap junction protein, alpha 3, 46kDa
GK2 glycerol kinase 2
GLT8D1 glycosyltransferase 8 domain containing 1
GMPR2 guanosine monophosphate reductase 2
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPR75 G protein-coupled receptor 75
GPR88 G protein-coupled receptor 88
GRAMD3 GRAM domain containing 3
GREB1L growth regulation by estrogen in breast cancer-like
H3F3C H3 histone, family 3C
HBBP1 hemoglobin, beta pseudogene 1
HEATR5A HEAT repeat containing 5A
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HNMT histamine N-methyltransferase
HNRNPK heterogeneous nuclear ribonucleoprotein K
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1
IGFBP6 insulin-like growth factor binding protein 6
IL10RA interleukin 10 receptor, alpha
IL1R2 interleukin 1 receptor, type II
IL23A interleukin 23, alpha subunit p19
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
INMT indolethylamine N-methyltransferase
INTS10 integrator complex subunit 10
INTU inturned planar cell polarity protein
IPO11 importin 11
IPO9 importin 9
IRGC immunity-related GTPase family, cinema
ITGAV integrin, alpha V
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
IZUMO1R IZUMO1 receptor, JUNO
JADE1 jade family PHD finger 1
JAK1 Janus kinase 1
JAM2 junctional adhesion molecule 2
JKAMP JNK1/MAPK8-associated membrane protein
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCNT2 potassium channel, sodium activated subfamily T, member 2
KDM5D lysine (K)-specific demethylase 5D
KDM7A lysine (K)-specific demethylase 7A
KIAA0391 KIAA0391
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF5 Kruppel-like factor 5 (intestinal)
KLF9 Kruppel-like factor 9
KLHDC8B kelch domain containing 8B
KLK8 kallikrein-related peptidase 8
KRTAP5-6 keratin associated protein 5-6
KSR2 kinase suppressor of ras 2
LAPTM4A lysosomal protein transmembrane 4 alpha
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LEPR leptin receptor
LIMK2 LIM domain kinase 2
LMOD1 leiomodin 1 (smooth muscle)
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LOC649330
LPL lipoprotein lipase
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LUZP6 leucine zipper protein 6
LYPLAL1 lysophospholipase-like 1
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MARVELD3 MARVEL domain containing 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MAT2A methionine adenosyltransferase II, alpha
MBIP MAP3K12 binding inhibitory protein 1
MEIG1 meiosis/spermiogenesis associated 1
MESTIT1 MEST intronic transcript 1, antisense RNA
METTL6 methyltransferase like 6
MEX3C mex-3 RNA binding family member C
MFSD11 major facilitator superfamily domain containing 11
MGAT4C MGAT4 family, member C
MKRN2 makorin ring finger protein 2
MKX mohawk homeobox
MLIP muscular LMNA-interacting protein
MMP27 matrix metallopeptidase 27
MORF4 mortality factor 4 (pseudogene)
MYH15 myosin, heavy chain 15
MYOT myotilin
NAV2 neuron navigator 2
NCF1C neutrophil cytosolic factor 1C pseudogene
NEBL nebulette
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEK4 NIMA-related kinase 4
NOTCH2 notch 2
NOTCH2NL notch 2 N-terminal like
NOV nephroblastoma overexpressed
NT5C2 5'-nucleotidase, cytosolic II
NT5DC3 5'-nucleotidase domain containing 3
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OGN osteoglycin
OLFML2B olfactomedin-like 2B
OMD osteomodulin
OR4N5 olfactory receptor, family 4, subfamily N, member 5
OR4Q3 olfactory receptor, family 4, subfamily Q, member 3
OR52A4P olfactory receptor, family 52, subfamily A, member 4, pseudogene
OR52L1 olfactory receptor, family 52, subfamily L, member 1
OR56B1 olfactory receptor, family 56, subfamily B, member 1
OR6S1 olfactory receptor, family 6, subfamily S, member 1
OR6X1 olfactory receptor, family 6, subfamily X, member 1
OXSR1 oxidative stress responsive 1
PAM peptidylglycine alpha-amidating monooxygenase
PARD3 par-3 family cell polarity regulator
PCDHA6 protocadherin alpha 6
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGB4 protocadherin gamma subfamily B, 4
PCNAP1 proliferating cell nuclear antigen pseudogene 1
PDCD6IP programmed cell death 6 interacting protein
PDE4DIP phosphodiesterase 4D interacting protein
PDE8B phosphodiesterase 8B
PEX19 peroxisomal biogenesis factor 19
PGA3 pepsinogen 3, group I (pepsinogen A)
PGA4 pepsinogen 4, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKDREJ polycystin (PKD) family receptor for egg jelly
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
PLAC8 placenta-specific 8
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
PMPCB peptidase (mitochondrial processing) beta
PNLIPRP1 pancreatic lipase-related protein 1
PNPLA8 patatin-like phospholipase domain containing 8
POTEE POTE ankyrin domain family, member E
PPP1R2P1 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1
PPP5C protein phosphatase 5, catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKX protein kinase, X-linked
PRLHR prolactin releasing hormone receptor
PRMT9 protein arginine methyltransferase 9
PTGDR prostaglandin D2 receptor (DP)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PXYLP1 2-phosphoxylose phosphatase 1
QRICH1 glutamine-rich 1
RAB10 RAB10, member RAS oncogene family
RAB18 RAB18, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RANBP3L RAN binding protein 3-like
RANBP6 RAN binding protein 6
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBL2 retinoblastoma-like 2
RBM17 RNA binding motif protein 17
REPS1 RALBP1 associated Eps domain containing 1
RFC5 replication factor C (activator 1) 5, 36.5kDa
RFT1 RFT1 homolog (S. cerevisiae)
RGAG1 retrotransposon gag domain containing 1
RGPD8 RANBP2-like and GRIP domain containing 8
RHOA ras homolog family member A
RIC1 RAB6A GEF complex partner 1
RNASE6 ribonuclease, RNase A family, k6
RNASE9 ribonuclease, RNase A family, 9 (non-active)
RNF141 ring finger protein 141
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF32 ring finger protein 32
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPL19P12 ribosomal protein L19 pseudogene 12
RPL29P2 ribosomal protein L29 pseudogene 2
RTN1 reticulon 1
RXRG retinoid X receptor, gamma
S1PR3 sphingosine-1-phosphate receptor 3
SBF1P1 SET binding factor 1 pseudogene 1
SCARA5 scavenger receptor class A, member 5
SCN7A sodium channel, voltage gated, type VII alpha subunit
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
SELK selenoprotein K
SELPLG selectin P ligand
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SETD2 SET domain containing 2
SETMAR SET domain and mariner transposase fusion gene
SFMBT2 Scm-like with four mbt domains 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A9 solute carrier family 16, member 9
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC39A11 solute carrier family 39, member 11
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMCP sperm mitochondria-associated cysteine-rich protein
SMIM14 small integral membrane protein 14
SORBS1 sorbin and SH3 domain containing 1
SP7 Sp7 transcription factor
SPANXA2 SPANX family, member A2
SPANXC SPANX family, member C
SPARCL1 SPARC-like 1 (hevin)
SPICE1 spindle and centriole associated protein 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STIM1 stromal interaction molecule 1
STK17B serine/threonine kinase 17b
STON1-GTF2A1L STON1-GTF2A1L readthrough
STX12 syntaxin 12
SUFU suppressor of fused homolog (Drosophila)
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4
SUMO1P1 SUMO1 pseudogene 1
SYT6 synaptotagmin VI
TAS2R38 taste receptor, type 2, member 38
TBC1D5 TBC1 domain family, member 5
TBCK TBC1 domain containing kinase
TCAIM T cell activation inhibitor, mitochondrial
TCP11 t-complex 11, testis-specific
TEX36 testis expressed 36
TGM7 transglutaminase 7
THUMPD3 THUMP domain containing 3
TIMP4 TIMP metallopeptidase inhibitor 4
TKTL1 transketolase-like 1
TLR4 toll-like receptor 4
TMEM14E transmembrane protein 14E
TMEM184C transmembrane protein 184C
TMEM30A transmembrane protein 30A
TMEM43 transmembrane protein 43
TMEM86A transmembrane protein 86A
TNNC1 troponin C type 1 (slow)
TNNI3K TNNI3 interacting kinase
TPI1P2 triosephosphate isomerase 1 pseudogene 2
TPM1 tropomyosin 1 (alpha)
TRAK1 trafficking protein, kinesin binding 1
TRIM42 tripartite motif containing 42
TSHR thyroid stimulating hormone receptor
TSPAN2 tetraspanin 2
TTC24 tetratricopeptide repeat domain 24
TTTY18 testis-specific transcript, Y-linked 18 (non-protein coding)
UBE2H ubiquitin-conjugating enzyme E2H
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
ULK4 unc-51 like kinase 4
UNC13B unc-13 homolog B (C. elegans)
UPB1 ureidopropionase, beta
UPK1B uroplakin 1B
USP15 ubiquitin specific peptidase 15
UTRN utrophin
UTS2B urotensin 2B
VPREB1 pre-B lymphocyte 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR48 WD repeat domain 48
WDR82 WD repeat domain 82
WLS wntless Wnt ligand secretion mediator
WNK2 WNK lysine deficient protein kinase 2
ZBED3 zinc finger, BED-type containing 3
ZCWPW2 zinc finger, CW type with PWWP domain 2
ZDHHC3 zinc finger, DHHC-type containing 3
ZNF525 zinc finger protein 525
ZNF589 zinc finger protein 589
ZNF619 zinc finger protein 619

low expression

Symbol Name
ADNP2 ADNP homeobox 2
RBFA ribosome binding factor A (putative)