Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

437 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACRV1 acrosomal vesicle protein 1
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTSL3 ADAMTS-like 3
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADK adenosine kinase
AGO1 argonaute RISC catalytic component 1
AGO3 argonaute RISC catalytic component 3
AHNAK AHNAK nucleoprotein
AK8 adenylate kinase 8
AKAP13 A kinase (PRKA) anchor protein 13
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL1 angiomotin like 1
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD44 ankyrin repeat domain 44
ANOS1 anosmin 1
ANTXR1 anthrax toxin receptor 1
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AR androgen receptor
ATF6 activating transcription factor 6
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATL3 atlastin GTPase 3
ATP11AUN ATP11A upstream neighbor
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
B3GALTL beta 1,3-galactosyltransferase-like
B3GAT2 beta-1,3-glucuronyltransferase 2
BARD1 BRCA1 associated RING domain 1
BBS1 Bardet-Biedl syndrome 1
BBX bobby sox homolog (Drosophila)
BCL9 B-cell CLL/lymphoma 9
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
C12ORF56 chromosome 12 open reading frame 56
C14ORF132 chromosome 14 open reading frame 132
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF198 chromosome 1 open reading frame 198
C1ORF94 chromosome 1 open reading frame 94
C2ORF88 chromosome 2 open reading frame 88
C6ORF89 chromosome 6 open reading frame 89
C8ORF34 chromosome 8 open reading frame 34
CAT catalase
CC2D2A coiled-coil and C2 domain containing 2A
CCDC144B coiled-coil domain containing 144B (pseudogene)
CCDC169 coiled-coil domain containing 169
CCDC170 coiled-coil domain containing 170
CCDC177 coiled-coil domain containing 177
CCDC40 coiled-coil domain containing 40
CCDC80 coiled-coil domain containing 80
CD84 CD84 molecule
CDH7 cadherin 7, type 2
CDO1 cysteine dioxygenase type 1
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CEP85L centrosomal protein 85kDa-like
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLSTN2 calsyntenin 2
CLTCL1 clathrin, heavy chain-like 1
CLUAP1 clusterin associated protein 1
CNBD1 cyclic nucleotide binding domain containing 1
CNTN1 contactin 1
COL28A1 collagen, type XXVIII, alpha 1
COMMD2 COMM domain containing 2
CPNE2 copine II
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CRB2 crumbs family member 2
CSPP1 centrosome and spindle pole associated protein 1
CTNND2 catenin (cadherin-associated protein), delta 2
CTSH cathepsin H
CXADRP3 coxsackie virus and adenovirus receptor pseudogene 3
CXXC4 CXXC finger protein 4
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DAAM2 dishevelled associated activator of morphogenesis 2
DCAF5 DDB1 and CUL4 associated factor 5
DCDC1 doublecortin domain containing 1
DCLK1 doublecortin-like kinase 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEPTOR DEP domain containing MTOR-interacting protein
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFNA5 deafness, autosomal dominant 5
DHRS4-AS1 DHRS4 antisense RNA 1
DICER1 dicer 1, ribonuclease type III
DLEC1 deleted in lung and esophageal cancer 1
DMKN dermokine
DNAH7 dynein, axonemal, heavy chain 7
DNAL1 dynein, axonemal, light chain 1
DOCK10 dedicator of cytokinesis 10
DOCK7 dedicator of cytokinesis 7
DPEP3 dipeptidase 3
DUOX1 dual oxidase 1
DUOXA1 dual oxidase maturation factor 1
DUSP18 dual specificity phosphatase 18
DUSP22 dual specificity phosphatase 22
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDA ectodysplasin A
EDNRA endothelin receptor type A
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3
ELMO2 engulfment and cell motility 2
EML1 echinoderm microtubule associated protein like 1
ENAH enabled homolog (Drosophila)
ENKUR enkurin, TRPC channel interacting protein
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
ERCC6 excision repair cross-complementation group 6
EXPH5 exophilin 5
EYA3 EYA transcriptional coactivator and phosphatase 3
EZR ezrin
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM151B family with sequence similarity 151, member B
FAM182A family with sequence similarity 182, member A
FAM229B family with sequence similarity 229, member B
FAM45B family with sequence similarity 45, member A pseudogene
FAM86B2 family with sequence similarity 86, member B2
FANK1 fibronectin type III and ankyrin repeat domains 1
FAT1 FAT atypical cadherin 1
FBXO36 F-box protein 36
FIGN fidgetin
FLNB filamin B, beta
FMN2 formin 2
FOXE1 forkhead box E1
FOXP2 forkhead box P2
FREM2 FRAS1 related extracellular matrix protein 2
FRY furry homolog (Drosophila)
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
FZD3 frizzled class receptor 3
GAN gigaxonin
GAREM GRB2 associated, regulator of MAPK1
GATA3 GATA binding protein 3
GBE1 glucan (1,4-alpha-), branching enzyme 1
GDF7 growth differentiation factor 7
GIGYF2 GRB10 interacting GYF protein 2
GINM1 glycoprotein integral membrane 1
GJA1 gap junction protein, alpha 1, 43kDa
GLIS3 GLIS family zinc finger 3
GLUD2 glutamate dehydrogenase 2
GOLGA6A golgin A6 family, member A
GOLIM4 golgi integral membrane protein 4
GRAMD3 GRAM domain containing 3
GREB1L growth regulation by estrogen in breast cancer-like
GRHL1 grainyhead-like 1 (Drosophila)
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2IRD2B GTF2I repeat domain containing 2B
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
H3F3C H3 histone, family 3C
HEATR5A HEAT repeat containing 5A
HMBOX1 homeobox containing 1
HPSE heparanase
HPSE2 heparanase 2 (inactive)
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFT140 intraflagellar transport 140
IGSF1 immunoglobulin superfamily, member 1
IGSF3 immunoglobulin superfamily, member 3
IL17RD interleukin 17 receptor D
IPO11 importin 11
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1
IRF8 interferon regulatory factor 8
ITM2B integral membrane protein 2B
ITSN1 intersectin 1 (SH3 domain protein)
IVNS1ABP influenza virus NS1A binding protein
IYD iodotyrosine deiodinase
JADE3 jade family PHD finger 3
JAK1 Janus kinase 1
KAAG1 kidney associated antigen 1
KANK2 KN motif and ankyrin repeat domains 2
KAT6A K(lysine) acetyltransferase 6A
KATNAL1 katanin p60 subunit A-like 1
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCTD20 potassium channel tetramerization domain containing 20
KIAA0355 KIAA0355
KIAA1549 KIAA1549
KIF1B kinesin family member 1B
KIF27 kinesin family member 27
KRT33A keratin 33A, type I
LDLRAD1 low density lipoprotein receptor class A domain containing 1
LHFP lipoma HMGIC fusion partner
LIMCH1 LIM and calponin homology domains 1
LINC00310 long intergenic non-protein coding RNA 310
LIPG lipase, endothelial
LIX1 Lix1 homolog (chicken)
LNPEP leucyl/cystinyl aminopeptidase
LOC100130987 uncharacterized LOC100130987
LOC643923 uncharacterized LOC643923
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPIN1 lipin 1
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
LRRC3 leucine rich repeat containing 3
LTBP4 latent transforming growth factor beta binding protein 4
LUZP2 leucine zipper protein 2
LZIC leucine zipper and CTNNBIP1 domain containing
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7D3 MAP7 domain containing 3
MAST4 microtubule associated serine/threonine kinase family member 4
MED4 mediator complex subunit 4
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGA MGA, MAX dimerization protein
MGAT4C MGAT4 family, member C
MICA MHC class I polypeptide-related sequence A
MKX mohawk homeobox
MLF1 myeloid leukemia factor 1
MMEL1 membrane metallo-endopeptidase-like 1
MORF4L1 mortality factor 4 like 1
MORN1 MORN repeat containing 1
MPDZ multiple PDZ domain protein
MPEG1 macrophage expressed 1
MRPS31 mitochondrial ribosomal protein S31
MSTN myostatin
MTF1 metal-regulatory transcription factor 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC4 mucin 4, cell surface associated
MYLIP myosin regulatory light chain interacting protein
NADK2 NAD kinase 2, mitochondrial
NCR1 natural cytotoxicity triggering receptor 1
NEK1 NIMA-related kinase 1
NEK11 NIMA-related kinase 11
NEK9 NIMA-related kinase 9
NFIB nuclear factor I/B
NHLRC2 NHL repeat containing 2
NKAIN3 Na+/K+ transporting ATPase interacting 3
NLRP14 NLR family, pyrin domain containing 14
NOTCH2 notch 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUMB numb homolog (Drosophila)
NUTM1 NUT midline carcinoma, family member 1
OGFRL1 opioid growth factor receptor-like 1
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR51I2 olfactory receptor, family 51, subfamily I, member 2
OR52A4P olfactory receptor, family 52, subfamily A, member 4, pseudogene
OR6C4 olfactory receptor, family 6, subfamily C, member 4
OR8K1 olfactory receptor, family 8, subfamily K, member 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
OSR2 odd-skipped related transciption factor 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAM peptidylglycine alpha-amidating monooxygenase
PARD3 par-3 family cell polarity regulator
PARD3B par-3 family cell polarity regulator beta
PATE1 prostate and testis expressed 1
PATE2 prostate and testis expressed 2
PATE3 prostate and testis expressed 3
PCDH10 protocadherin 10
PCDHA10 protocadherin alpha 10
PCDHA4 protocadherin alpha 4
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGB5 protocadherin gamma subfamily B, 5
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDIA5 protein disulfide isomerase family A, member 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER3 period circadian clock 3
PEX11A peroxisomal biogenesis factor 11 alpha
PHEX phosphate regulating endopeptidase homolog, X-linked
PI15 peptidase inhibitor 15
PKDREJ polycystin (PKD) family receptor for egg jelly
PLCD1 phospholipase C, delta 1
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLXDC2 plexin domain containing 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRR5L proline rich 5 like
PRSS54 protease, serine, 54
PRUNE2 prune homolog 2 (Drosophila)
PTAFR platelet-activating factor receptor
PTCH2 patched 2
PTCHD1 patched domain containing 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRG protein tyrosine phosphatase, receptor type, G
PURA purine-rich element binding protein A
RBM23 RNA binding motif protein 23
RDX radixin
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RHPN2 rhophilin, Rho GTPase binding protein 2
RIN2 Ras and Rab interactor 2
RIPK2 receptor-interacting serine-threonine kinase 2
RNF182 ring finger protein 182
RNF39 ring finger protein 39
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPE65 retinal pigment epithelium-specific protein 65kDa
RPGRIP1L RPGRIP1-like
RSPO3 R-spondin 3
SALL2 spalt-like transcription factor 2
SAMD15 sterile alpha motif domain containing 15
SBF2 SET binding factor 2
SCGB2B2 secretoglobin, family 2B, member 2
SEC1P secretory blood group 1, pseudogene
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SENP8 SUMO/sentrin specific peptidase family member 8
SEPT7P9 septin 7 pseudogene 9
SESN3 sestrin 3
SFMBT2 Scm-like with four mbt domains 2
SFTPD surfactant protein D
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIDT1 SID1 transmembrane family, member 1
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A53 solute carrier family 25, member 53
SLC35E4 solute carrier family 35, member E4
SLC38A4 solute carrier family 38, member 4
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
SMAD9 SMAD family member 9
SMAP1 small ArfGAP 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNX18 sorting nexin 18
SOCS6 suppressor of cytokine signaling 6
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SORBS1 sorbin and SH3 domain containing 1
SORD sorbitol dehydrogenase
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPATA12 spermatogenesis associated 12
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPOP speckle-type POZ protein
SPTBN1 spectrin, beta, non-erythrocytic 1
SSBP2 single-stranded DNA binding protein 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STON1 stonin 1
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNM synemin, intermediate filament protein
SYT6 synaptotagmin VI
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAS2R41 taste receptor, type 2, member 41
TC2N tandem C2 domains, nuclear
TCP11L2 t-complex 11, testis-specific-like 2
TESK2 testis-specific kinase 2
TET1 tet methylcytosine dioxygenase 1
TET3 tet methylcytosine dioxygenase 3
TFDP3 transcription factor Dp family, member 3
TG thyroglobulin
TGFBR3 transforming growth factor, beta receptor III
THOC2 THO complex 2
THRAP3 thyroid hormone receptor associated protein 3
TJP2 tight junction protein 2
TMC1 transmembrane channel-like 1
TMEM184C transmembrane protein 184C
TMEM231 transmembrane protein 231
TMEM232 transmembrane protein 232
TMEM47 transmembrane protein 47
TMIGD1 transmembrane and immunoglobulin domain containing 1
TMOD3 tropomodulin 3 (ubiquitous)
TMX1 thioredoxin-related transmembrane protein 1
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIK TRAF2 and NCK interacting kinase
TNK1 tyrosine kinase, non-receptor, 1
TP53BP1 tumor protein p53 binding protein 1
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPO thyroid peroxidase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM56 tripartite motif containing 56
TRIP11 thyroid hormone receptor interactor 11
TSC22D2 TSC22 domain family, member 2
TSHR thyroid stimulating hormone receptor
TTC30A tetratricopeptide repeat domain 30A
TTC30B tetratricopeptide repeat domain 30B
TTLL5 tubulin tyrosine ligase-like family member 5
TTTY13 testis-specific transcript, Y-linked 13 (non-protein coding)
TUBGCP3 tubulin, gamma complex associated protein 3
UBL3 ubiquitin-like 3
UNC13B unc-13 homolog B (C. elegans)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP44 ubiquitin specific peptidase 44
UTRN utrophin
VANGL1 VANGL planar cell polarity protein 1
VANGL2 VANGL planar cell polarity protein 2
VCAM1 vascular cell adhesion molecule 1
VCL vinculin
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR19 WD repeat domain 19
WDR31 WD repeat domain 31
WDR35 WD repeat domain 35
WIPF2 WAS/WASL interacting protein family, member 2
WNT2B wingless-type MMTV integration site family, member 2B
WNT5A wingless-type MMTV integration site family, member 5A
WNT9B wingless-type MMTV integration site family, member 9B
YAP1 Yes-associated protein 1
ZBTB20 zinc finger and BTB domain containing 20
ZBTB7C zinc finger and BTB domain containing 7C
ZC3H13 zinc finger CCCH-type containing 13
ZC3H14 zinc finger CCCH-type containing 14
ZDHHC3 zinc finger, DHHC-type containing 3
ZFHX4 zinc finger homeobox 4
ZFYVE1 zinc finger, FYVE domain containing 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF132 zinc finger protein 132
ZNF281 zinc finger protein 281
ZNF295-AS1 ZNF295 antisense RNA 1
ZNF396 zinc finger protein 396
ZNF417 zinc finger protein 417
ZNF474 zinc finger protein 474
ZNF487 zinc finger protein 487
ZNF497 zinc finger protein 497
ZNF532 zinc finger protein 532
ZNF592 zinc finger protein 592
ZNF609 zinc finger protein 609
ZNF619 zinc finger protein 619
ZNF710 zinc finger protein 710
ZNF772 zinc finger protein 772
ZNF81 zinc finger protein 81
ZNF823 zinc finger protein 823
ZSCAN20 zinc finger and SCAN domain containing 20

low expression

Symbol Name
ANAPC5 anaphase promoting complex subunit 5
ANKLE2 ankyrin repeat and LEM domain containing 2
DENR density-regulated protein
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
RAN RAN, member RAS oncogene family
RNF10 ring finger protein 10
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
SORBS3 sorbin and SH3 domain containing 3
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
ZNF26 zinc finger protein 26