Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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330 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABI1 abl-interactor 1
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADCY2 adenylate cyclase 2 (brain)
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AHCTF1 AT hook containing transcription factor 1
AHCYL1 adenosylhomocysteinase-like 1
ALDOB aldolase B, fructose-bisphosphate
ANKRD46 ankyrin repeat domain 46
ANTXR1 anthrax toxin receptor 1
APIP APAF1 interacting protein
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARHGAP12 Rho GTPase activating protein 12
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARMC1 armadillo repeat containing 1
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASB3 ankyrin repeat and SOCS box containing 3
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATG4C autophagy related 4C, cysteine peptidase
ATP11AUN ATP11A upstream neighbor
BHLHE41 basic helix-loop-helix family, member e41
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C12ORF29 chromosome 12 open reading frame 29
C12ORF75 chromosome 12 open reading frame 75
C12ORF77 chromosome 12 open reading frame 77
C21ORF91 chromosome 21 open reading frame 91
C22ORF46 chromosome 22 open reading frame 46
C2ORF69 chromosome 2 open reading frame 69
C8ORF58 chromosome 8 open reading frame 58
C9ORF66 chromosome 9 open reading frame 66
CARD18 caspase recruitment domain family, member 18
CCDC172 coiled-coil domain containing 172
CCDC25 coiled-coil domain containing 25
CCDC91 coiled-coil domain containing 91
CDNF cerebral dopamine neurotrophic factor
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CENPQ centromere protein Q
CEP70 centrosomal protein 70kDa
CHMP7 charged multivesicular body protein 7
CHP2 calcineurin-like EF-hand protein 2
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CLCA2 chloride channel accessory 2
CLDN17 claudin 17
CLDND1 claudin domain containing 1
CNBD1 cyclic nucleotide binding domain containing 1
CNGA1 cyclic nucleotide gated channel alpha 1
CNOT7 CCR4-NOT transcription complex, subunit 7
CNTNAP4 contactin associated protein-like 4
COL4A5 collagen, type IV, alpha 5
COPS5 COP9 signalosome subunit 5
CPA2 carboxypeptidase A2 (pancreatic)
CPNE3 copine III
CRBN cereblon
CREG1 cellular repressor of E1A-stimulated genes 1
CRIPT cysteine-rich PDZ-binding protein
CSRP2 cysteine and glycine-rich protein 2
CSTL1 cystatin-like 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYCSP52 cytochrome c, somatic pseudogene 52
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCTN6 dynactin 6
DEFB124 defensin, beta 124
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAH17 dynein, axonemal, heavy chain 17
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DPYSL2 dihydropyrimidinase-like 2
DTX4 deltex 4, E3 ubiquitin ligase
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EBAG9 estrogen receptor binding site associated, antigen, 9
EFHB EF-hand domain family, member B
EIF3J eukaryotic translation initiation factor 3, subunit J
EIF5B eukaryotic translation initiation factor 5B
ELP3 elongator acetyltransferase complex subunit 3
EMC2 ER membrane protein complex subunit 2
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ERBB2IP erbb2 interacting protein
ERMN ermin, ERM-like protein
EVI2A ecotropic viral integration site 2A
FAIM Fas apoptotic inhibitory molecule
FAM134B family with sequence similarity 134, member B
FAM227B family with sequence similarity 227, member B
FAM45A family with sequence similarity 45, member A
FAR1 fatty acyl CoA reductase 1
FAXDC2 fatty acid hydroxylase domain containing 2
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FGF20 fibroblast growth factor 20
FNTA farnesyltransferase, CAAX box, alpha
FNTB farnesyltransferase, CAAX box, beta
FOLH1B folate hydrolase 1B
FOLR2 folate receptor 2 (fetal)
FRG2B FSHD region gene 2 family, member B
FRG2C FSHD region gene 2 family, member C
FRMD3 FERM domain containing 3
FSD2 fibronectin type III and SPRY domain containing 2
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GDF2 growth differentiation factor 2
GHSR growth hormone secretagogue receptor
GLT6D1 glycosyltransferase 6 domain containing 1
GLTP glycolipid transfer protein
GMFB glia maturation factor, beta
GOLGA7 golgin A7
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPM6B glycoprotein M6B
GPN3 GPN-loop GTPase 3
GPR34 G protein-coupled receptor 34
GTF2B general transcription factor IIB
HCG22 HLA complex group 22
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HHLA2 HERV-H LTR-associating 2
HPGDS hematopoietic prostaglandin D synthase
HPSE heparanase
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFNGR1 interferon gamma receptor 1
IGSF6 immunoglobulin superfamily, member 6
IL33 interleukin 33
IL36RN interleukin 36 receptor antagonist
IMPAD1 inositol monophosphatase domain containing 1
JKAMP JNK1/MAPK8-associated membrane protein
KANK4 KN motif and ankyrin repeat domains 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK18 potassium channel, two pore domain subfamily K, member 18
KCTD21 potassium channel tetramerization domain containing 21
KCTD9 potassium channel tetramerization domain containing 9
KIAA0196 KIAA0196
KIAA1033 KIAA1033
KIF1BP KIF1 binding protein
KRCC1 lysine-rich coiled-coil 1
KRT33A keratin 33A, type I
KRTAP9-9 keratin associated protein 9-9
LEPROTL1 leptin receptor overlapping transcript-like 1
LINC00028 long intergenic non-protein coding RNA 28
LIX1 Lix1 homolog (chicken)
LMBRD1 LMBR1 domain containing 1
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LOC646999 akirin 1 pseudogene
LPAR5 lysophosphatidic acid receptor 5
LRRC39 leucine rich repeat containing 39
LSM1 LSM1, U6 small nuclear RNA associated
LY86 lymphocyte antigen 86
LYPLAL1 lysophospholipase-like 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAK16 MAK16 homolog (S. cerevisiae)
MAMDC2 MAM domain containing 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MCPH1 microcephalin 1
MEIG1 meiosis/spermiogenesis associated 1
MEP1A meprin A, alpha (PABA peptide hydrolase)
MINA MYC induced nuclear antigen
MKX mohawk homeobox
MNDA myeloid cell nuclear differentiation antigen
MOB3B MOB kinase activator 3B
MOBP myelin-associated oligodendrocyte basic protein
MORC1 MORC family CW-type zinc finger 1
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
MTUS1 microtubule associated tumor suppressor 1
MYO1A myosin IA
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit
NANOS1 nanos homolog 1 (Drosophila)
NBN nibrin
NEK7 NIMA-related kinase 7
NEMF nuclear export mediator factor
NKAIN2 Na+/K+ transporting ATPase interacting 2
NKAPL NFKB activating protein-like
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OR1C1 olfactory receptor, family 1, subfamily C, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2A25 olfactory receptor, family 2, subfamily A, member 25
OR2G6 olfactory receptor, family 2, subfamily G, member 6
OR4N5 olfactory receptor, family 4, subfamily N, member 5
OR52E2 olfactory receptor, family 52, subfamily E, member 2
OR52I2 olfactory receptor, family 52, subfamily I, member 2
OR56B4 olfactory receptor, family 56, subfamily B, member 4
OR5K1 olfactory receptor, family 5, subfamily K, member 1
OR5K2 olfactory receptor, family 5, subfamily K, member 2
OR6B2 olfactory receptor, family 6, subfamily B, member 2
OR6B3 olfactory receptor, family 6, subfamily B, member 3
OSGIN2 oxidative stress induced growth inhibitor family member 2
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PAIP2 poly(A) binding protein interacting protein 2
PCDHA10 protocadherin alpha 10
PCDHGB3 protocadherin gamma subfamily B, 3
PCM1 pericentriolar material 1
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE11A phosphodiesterase 11A
PDILT protein disulfide isomerase-like, testis expressed
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX2 peroxisomal biogenesis factor 2
PHF10 PHD finger protein 10
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLP1 proteolipid protein 1
PMP2 peripheral myelin protein 2
POC1B POC1 centriolar protein B
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKG2 protein kinase, cGMP-dependent, type II
PROSC proline synthetase co-transcribed homolog (bacterial)
PRR5L proline rich 5 like
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRTFDC1 phosphoribosyl transferase domain containing 1
PSEN1 presenilin 1
PSG2 pregnancy specific beta-1-glycoprotein 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
QKI QKI, KH domain containing, RNA binding
RAB10 RAB10, member RAS oncogene family
RAB18 RAB18, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RAD21 RAD21 homolog (S. pombe)
RAP1A RAP1A, member of RAS oncogene family
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBM11 RNA binding motif protein 11
RBM17 RNA binding motif protein 17
RDX radixin
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REM1 RAS (RAD and GEM)-like GTP-binding 1
REP15 RAB15 effector protein
RIPK2 receptor-interacting serine-threonine kinase 2
RMDN1 regulator of microtubule dynamics 1
RNASE8 ribonuclease, RNase A family, 8
RNF13 ring finger protein 13
RNF170 ring finger protein 170
RNF32 ring finger protein 32
RTP3 receptor (chemosensory) transporter protein 3
RTTN rotatin
SAMD4A sterile alpha motif domain containing 4A
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SARAF store-operated calcium entry-associated regulatory factor
SBDS Shwachman-Bodian-Diamond syndrome
SCCPDH saccharopine dehydrogenase (putative)
SEC62 SEC62 homolog (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SEPT10 septin 10
SERP1 stress-associated endoplasmic reticulum protein 1
SFXN2 sideroflexin 2
SGK3 serum/glucocorticoid regulated kinase family, member 3
SH3BGRL SH3 domain binding glutamate-rich protein like
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC38A4 solute carrier family 38, member 4
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SMIM15 small integral membrane protein 15
SMIM19 small integral membrane protein 19
SNORA16B small nucleolar RNA, H/ACA box 16B
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
SNX16 sorting nexin 16
SNX18 sorting nexin 18
SNX2 sorting nexin 2
SNX24 sorting nexin 24
SNX6 sorting nexin 6
SOCS6 suppressor of cytokine signaling 6
SORBS1 sorbin and SH3 domain containing 1
SPANXN2 SPANX family, member N2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRP54 signal recognition particle 54kDa
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
STX7 syntaxin 7
STXBP3 syntaxin binding protein 3
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4
SUMO1P1 SUMO1 pseudogene 1
SYNDIG1 synapse differentiation inducing 1
TAAR5 trace amine associated receptor 5
TAAR8 trace amine associated receptor 8
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAS2R4 taste receptor, type 2, member 4
TBC1D12 TBC1 domain family, member 12
TC2N tandem C2 domains, nuclear
TCEA1 transcription elongation factor A (SII), 1
TDGF1 teratocarcinoma-derived growth factor 1
TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TEX37 testis expressed 37
THAP1 THAP domain containing, apoptosis associated protein 1
TLR7 toll-like receptor 7
TM2D2 TM2 domain containing 2
TMEM106A transmembrane protein 106A
TMEM64 transmembrane protein 64
TMIGD1 transmembrane and immunoglobulin domain containing 1
TMIGD2 transmembrane and immunoglobulin domain containing 2
TRIM50 tripartite motif containing 50
TRIQK triple QxxK/R motif containing
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TTLL5 tubulin tyrosine ligase-like family member 5
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBXN2A UBX domain protein 2A
UBXN8 UBX domain protein 8
UGT8 UDP glycosyltransferase 8
ULK2 unc-51 like autophagy activating kinase 2
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast)
VAMP3 vesicle-associated membrane protein 3
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VDAC3 voltage-dependent anion channel 3
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
WRB tryptophan rich basic protein
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZCWPW2 zinc finger, CW type with PWWP domain 2
ZDHHC19 zinc finger, DHHC-type containing 19
ZDHHC2 zinc finger, DHHC-type containing 2
ZNF143 zinc finger protein 143
ZNHIT6 zinc finger, HIT-type containing 6

low expression

Symbol Name
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
NLRC3 NLR family, CARD domain containing 3
RNF123 ring finger protein 123
SCAP SREBF chaperone
TMCO6 transmembrane and coiled-coil domains 6
USP19 ubiquitin specific peptidase 19