Brain Lower Grade Glioma_LGG_TCGA-HT-7479-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

350 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-7479-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACY3 aminoacylase 3
ADAMTSL3 ADAMTS-like 3
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ADD3 adducin 3 (gamma)
ADRB2 adrenoceptor beta 2, surface
AICDA activation-induced cytidine deaminase
AK3 adenylate kinase 3
AKR1C1 aldo-keto reductase family 1, member C1
AKTIP AKT interacting protein
ALAD aminolevulinate dehydratase
AMOT angiomotin
AMPD3 adenosine monophosphate deaminase 3
ANKRD40 ankyrin repeat domain 40
ANLN anillin, actin binding protein
ANTXR1 anthrax toxin receptor 1
ARHGAP21 Rho GTPase activating protein 21
ARHGAP6 Rho GTPase activating protein 6
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARRDC4 arrestin domain containing 4
ASPA aspartoacylase
ATG4C autophagy related 4C, cysteine peptidase
ATP1A1-AS1 ATP1A1 antisense RNA 1
BHLHE41 basic helix-loop-helix family, member e41
BLNK B-cell linker
BSPRY B-box and SPRY domain containing
BTBD8 BTB (POZ) domain containing 8
BTG2 BTG family, member 2
C10ORF128 chromosome 10 open reading frame 128
C12ORF75 chromosome 12 open reading frame 75
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C21ORF91 chromosome 21 open reading frame 91
C22ORF46 chromosome 22 open reading frame 46
C4ORF3 chromosome 4 open reading frame 3
CALR3 calreticulin 3
CASC2 cancer susceptibility candidate 2 (non-protein coding)
CCDC122 coiled-coil domain containing 122
CCDC141 coiled-coil domain containing 141
CCDC25 coiled-coil domain containing 25
CCL3 chemokine (C-C motif) ligand 3
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCL4 chemokine (C-C motif) ligand 4
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CFHR4 complement factor H-related 4
CH25H cholesterol 25-hydroxylase
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHMP2B charged multivesicular body protein 2B
CHP2 calcineurin-like EF-hand protein 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLCA2 chloride channel accessory 2
CLCA4 chloride channel accessory 4
CLDND1 claudin domain containing 1
CLEC9A C-type lectin domain family 9, member A
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
CNKSR3 CNKSR family member 3
CNTNAP4 contactin associated protein-like 4
COPS5 COP9 signalosome subunit 5
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXORF21 chromosome X open reading frame 21
CYS1 cystin 1
DAAM2 dishevelled associated activator of morphogenesis 2
DAO D-amino-acid oxidase
DAZAP2 DAZ associated protein 2
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DCTN6 dynactin 6
DEFB118 defensin, beta 118
DEFB119 defensin, beta 119
DEFB123 defensin, beta 123
DHFRL1 dihydrofolate reductase-like 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAH17 dynein, axonemal, heavy chain 17
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DOCK5 dedicator of cytokinesis 5
DPRX divergent-paired related homeobox
DUSP22 dual specificity phosphatase 22
DUSP27 dual specificity phosphatase 27 (putative)
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EGR2 early growth response 2
ELOVL1 ELOVL fatty acid elongase 1
EMC2 ER membrane protein complex subunit 2
EML1 echinoderm microtubule associated protein like 1
ENKUR enkurin, TRPC channel interacting protein
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERMN ermin, ERM-like protein
ESD esterase D
EVI2A ecotropic viral integration site 2A
FA2H fatty acid 2-hydroxylase
FAIM Fas apoptotic inhibitory molecule
FAM105A family with sequence similarity 105, member A
FAM124A family with sequence similarity 124A
FAM129B family with sequence similarity 129, member B
FAM149B1 family with sequence similarity 149, member B1
FAM171A1 family with sequence similarity 171, member A1
FAM19A4 family with sequence similarity 19 (chemokine (C-C motif)-like), member A4
FAM229B family with sequence similarity 229, member B
FAM45A family with sequence similarity 45, member A
FAM45B family with sequence similarity 45, member A pseudogene
FAXDC2 fatty acid hydroxylase domain containing 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FFAR3 free fatty acid receptor 3
FGF1 fibroblast growth factor 1 (acidic)
FLNB filamin B, beta
FNBP1L formin binding protein 1-like
FNTA farnesyltransferase, CAAX box, alpha
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLH1B folate hydrolase 1B
FOLR2 folate receptor 2 (fetal)
FOXO4 forkhead box O4
FOXQ1 forkhead box Q1
FRYL FRY-like
FXYD4 FXYD domain containing ion transport regulator 4
GAB2 GRB2-associated binding protein 2
GALC galactosylceramidase
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GDF11 growth differentiation factor 11
GIMAP8 GTPase, IMAP family member 8
GJB1 gap junction protein, beta 1, 32kDa
GLTP glycolipid transfer protein
GMFB glia maturation factor, beta
GOLGA7 golgin A7
GPN3 GPN-loop GTPase 3
GPR183 G protein-coupled receptor 183
GPR62 G protein-coupled receptor 62
GPRC5B G protein-coupled receptor, class C, group 5, member B
GSDMC gasdermin C
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GTF2H5 general transcription factor IIH, polypeptide 5
HACD2 3-hydroxyacyl-CoA dehydratase 2
HHEX hematopoietically expressed homeobox
HHLA2 HERV-H LTR-associating 2
HMGB4 high mobility group box 4
HMSD histocompatibility (minor) serpin domain containing
HN1L hematological and neurological expressed 1-like
HOXD1 homeobox D1
HPGDS hematopoietic prostaglandin D synthase
HPSE2 heparanase 2 (inactive)
IDNK idnK, gluconokinase homolog (E. coli)
IER2 immediate early response 2
IER3 immediate early response 3
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B
IFT88 intraflagellar transport 88
IGIP IgA-inducing protein
IL1B interleukin 1, beta
IL33 interleukin 33
ILDR1 immunoglobulin-like domain containing receptor 1
IRF8 interferon regulatory factor 8
JKAMP JNK1/MAPK8-associated membrane protein
KANK4 KN motif and ankyrin repeat domains 4
KCTD21 potassium channel tetramerization domain containing 21
KCTD7 potassium channel tetramerization domain containing 7
KIAA0196 KIAA0196
KIF13B kinesin family member 13B
KIF1C kinesin family member 1C
KIF5B kinesin family member 5B
KLHL5 kelch-like family member 5
KLK6 kallikrein-related peptidase 6
KRT12 keratin 12, type I
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIMCH1 LIM and calponin homology domains 1
LIPA lipase A, lysosomal acid, cholesterol esterase
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMBRD1 LMBR1 domain containing 1
LMNTD1 lamin tail domain containing 1
LOC728024 chromosome X open reading frame 56 pseudogene
LPIN1 lipin 1
LRP2 low density lipoprotein receptor-related protein 2
LRRC8D leucine rich repeat containing 8 family, member D
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LURAP1 leucine rich adaptor protein 1
LY6K lymphocyte antigen 6 complex, locus K
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAMDC2 MAM domain containing 2
MAP4 microtubule-associated protein 4
MAP7 microtubule-associated protein 7
MBNL2 muscleblind-like splicing regulator 2
MBP myelin basic protein
MOB3B MOB kinase activator 3B
MOBP myelin-associated oligodendrocyte basic protein
MOG myelin oligodendrocyte glycoprotein
MORC1 MORC family CW-type zinc finger 1
MOSPD2 motile sperm domain containing 2
MPDZ multiple PDZ domain protein
MPEG1 macrophage expressed 1
MSRB3 methionine sulfoxide reductase B3
MTMR10 myotubularin related protein 10
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
MTUS1 microtubule associated tumor suppressor 1
MVB12B multivesicular body subunit 12B
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NDRG1 N-myc downstream regulated 1
NEK7 NIMA-related kinase 7
NET1 neuroepithelial cell transforming 1
NIPAL4 NIPA-like domain containing 4
NKAIN2 Na+/K+ transporting ATPase interacting 2
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
NT5DC1 5'-nucleotidase domain containing 1
OARD1 O-acyl-ADP-ribose deacylase 1
OCM2 oncomodulin 2
OPTN optineurin
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OR1I1 olfactory receptor, family 1, subfamily I, member 1
OR52B6 olfactory receptor, family 52, subfamily B, member 6
OR52N1 olfactory receptor, family 52, subfamily N, member 1
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2
OR6C1 olfactory receptor, family 6, subfamily C, member 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTC ornithine carbamoyltransferase
OTUD1 OTU deubiquitinase 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PAIP2B poly(A) binding protein interacting protein 2B
PAOX polyamine oxidase (exo-N4-amino)
PAQR6 progestin and adipoQ receptor family member VI
PCDH12 protocadherin 12
PEX2 peroxisomal biogenesis factor 2
PHF10 PHD finger protein 10
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIR pirin (iron-binding nuclear protein)
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLP1 proteolipid protein 1
PLRG1 pleiotropic regulator 1
PM20D1 peptidase M20 domain containing 1
PMP22 peripheral myelin protein 22
POC1B POC1 centriolar protein B
POU1F1 POU class 1 homeobox 1
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROSC proline synthetase co-transcribed homolog (bacterial)
PRR32 proline rich 32
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRTFDC1 phosphoribosyl transferase domain containing 1
PSEN1 presenilin 1
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB23 RAB23, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD51B RAD51 paralog B
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RBM17 RNA binding motif protein 17
RBP7 retinol binding protein 7, cellular
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RHD Rh blood group, D antigen
RMDN1 regulator of microtubule dynamics 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF13 ring finger protein 13
RNF130 ring finger protein 130
RNF141 ring finger protein 141
RNLS renalase, FAD-dependent amine oxidase
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNX1-IT1 RUNX1 intronic transcript 1
S1PR5 sphingosine-1-phosphate receptor 5
SAMD4A sterile alpha motif domain containing 4A
SAMD7 sterile alpha motif domain containing 7
SAP18 Sin3A-associated protein, 18kDa
SBDS Shwachman-Bodian-Diamond syndrome
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SCCPDH saccharopine dehydrogenase (putative)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2B2 secretoglobin, family 2B, member 2
SECISBP2L SECIS binding protein 2-like
SELPLG selectin P ligand
SEPP1 selenoprotein P, plasma, 1
SEPT10 septin 10
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SFT2D1 SFT2 domain containing 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIGLEC11 sialic acid binding Ig-like lectin 11
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNX18 sorting nexin 18
SOCS6 suppressor of cytokine signaling 6
SORBS1 sorbin and SH3 domain containing 1
SPDYC speedy/RINGO cell cycle regulator family member C
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST18 suppression of tumorigenicity 18, zinc finger
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
SVIP small VCP/p97-interacting protein
SYNJ2 synaptojanin 2
SYNPO2 synaptopodin 2
TAAR5 trace amine associated receptor 5
TARP TCR gamma alternate reading frame protein
TARSL2 threonyl-tRNA synthetase-like 2
TAS2R38 taste receptor, type 2, member 38
TBC1D12 TBC1 domain family, member 12
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TDGF1 teratocarcinoma-derived growth factor 1
TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3
TDRD7 tudor domain containing 7
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TESK2 testis-specific kinase 2
TEX37 testis expressed 37
TF transferrin
TFB1M transcription factor B1, mitochondrial
TGFB3 transforming growth factor, beta 3
THAP1 THAP domain containing, apoptosis associated protein 1
TJP2 tight junction protein 2
TMC7 transmembrane channel-like 7
TMEM144 transmembrane protein 144
TMEM52B transmembrane protein 52B
TNF tumor necrosis factor
TP53INP2 tumor protein p53 inducible nuclear protein 2
TRAK2 trafficking protein, kinesin binding 2
TRIM59 tripartite motif containing 59
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSPAN15 tetraspanin 15
TSPAN8 tetraspanin 8
TTLL5 tubulin tyrosine ligase-like family member 5
TTPA tocopherol (alpha) transfer protein
TTTY22 testis-specific transcript, Y-linked 22 (non-protein coding)
TTTY23 testis-specific transcript, Y-linked 23 (non-protein coding)
UGT8 UDP glycosyltransferase 8
USP46 ubiquitin specific peptidase 46
UTRN utrophin
VAMP3 vesicle-associated membrane protein 3
WNT9B wingless-type MMTV integration site family, member 9B
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWTR1 WW domain containing transcription regulator 1
ZCRB1 zinc finger CCHC-type and RNA binding motif 1
ZFAT-AS1 ZFAT antisense RNA 1
ZHX1 zinc fingers and homeoboxes 1
ZNF185 zinc finger protein 185 (LIM domain)

low expression

Symbol Name
FOXK2 forkhead box K2
SERF1A small EDRK-rich factor 1A (telomeric)
ZNF512 zinc finger protein 512