Brain Lower Grade Glioma_LGG_TCGA-HT-7468-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

425 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-7468-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABI2 abl-interactor 2
ACER2 alkaline ceramidase 2
ADGRB3 adhesion G protein-coupled receptor B3
ADGRV1 adhesion G protein-coupled receptor V1
AFAP1 actin filament associated protein 1
AFAP1L2 actin filament associated protein 1-like 2
AGPS alkylglycerone phosphate synthase
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALG9 ALG9, alpha-1,2-mannosyltransferase
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANGEL2 angel homolog 2 (Drosophila)
ANO5 anoctamin 5
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP12 Rho GTPase activating protein 12
ARL4A ADP-ribosylation factor-like 4A
ASCC3 activating signal cointegrator 1 complex subunit 3
ASTN1 astrotactin 1
ASXL2 additional sex combs like transcriptional regulator 2
ATRX alpha thalassemia/mental retardation syndrome X-linked
BCHE butyrylcholinesterase
BCLAF1 BCL2-associated transcription factor 1
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BROX BRO1 domain and CAAX motif containing
BRWD3 bromodomain and WD repeat domain containing 3
C11ORF30 chromosome 11 open reading frame 30
C12ORF49 chromosome 12 open reading frame 49
C14ORF105 chromosome 14 open reading frame 105
C14ORF132 chromosome 14 open reading frame 132
C14ORF37 chromosome 14 open reading frame 37
C2ORF80 chromosome 2 open reading frame 80
C3ORF17 chromosome 3 open reading frame 17
C4ORF45 chromosome 4 open reading frame 45
CADM2 cell adhesion molecule 2
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CANX calnexin
CAPN14 calpain 14
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCDC171 coiled-coil domain containing 171
CCDC88A coiled-coil domain containing 88A
CDC14B cell division cycle 14B
CDC73 cell division cycle 73
CDH13 cadherin 13
CDH18 cadherin 18, type 2
CEP350 centrosomal protein 350kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHURC1 churchill domain containing 1
CLCN3 chloride channel, voltage-sensitive 3
CLRN1-AS1 CLRN1 antisense RNA 1
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CPE carboxypeptidase E
CREB3L1 cAMP responsive element binding protein 3-like 1
CRYM-AS1 CRYM antisense RNA 1
CSMD1 CUB and Sushi multiple domains 1
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSO cathepsin O
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DACH1 dachshund family transcription factor 1
DACH2 dachshund family transcription factor 2
DCAF10 DDB1 and CUL4 associated factor 10
DCAF4 DDB1 and CUL4 associated factor 4
DCAF5 DDB1 and CUL4 associated factor 5
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DEFB126 defensin, beta 126
DENND1B DENN/MADD domain containing 1B
DEPDC4 DEP domain containing 4
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6
DGKB diacylglycerol kinase, beta 90kDa
DISC1 disrupted in schizophrenia 1
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18
DOCK1 dedicator of cytokinesis 1
DPY19L4 dpy-19-like 4 (C. elegans)
DRAM1 DNA-damage regulated autophagy modulator 1
DROSHA drosha, ribonuclease type III
DYM dymeclin
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EML5 echinoderm microtubule associated protein like 5
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC8 excision repair cross-complementation group 8
ETV1 ets variant 1
EXOC6B exocyst complex component 6B
EYS eyes shut homolog (Drosophila)
FAM168A family with sequence similarity 168, member A
FAM173B family with sequence similarity 173, member B
FAM178A family with sequence similarity 178, member A
FAM196A family with sequence similarity 196, member A
FAM205A family with sequence similarity 205, member A
FAM208A family with sequence similarity 208, member A
FAM21A family with sequence similarity 21, member A
FAM66C family with sequence similarity 66, member C
FAT3 FAT atypical cadherin 3
FCHO2 FCH domain only 2
FER fer (fps/fes related) tyrosine kinase
FKTN fukutin
FOXN3 forkhead box N3
FRMPD1 FERM and PDZ domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
FUBP3 far upstream element (FUSE) binding protein 3
G6PC glucose-6-phosphatase, catalytic subunit
GAB1 GRB2-associated binding protein 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GATSL2 GATS protein-like 2
GFRA1 GDNF family receptor alpha 1
GINM1 glycoprotein integral membrane 1
GLDC glycine dehydrogenase (decarboxylating)
GLP1R glucagon-like peptide 1 receptor
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GPATCH2L G patch domain containing 2-like
GPR161 G protein-coupled receptor 161
GPR45 G protein-coupled receptor 45
GPR75 G protein-coupled receptor 75
GPSM2 G-protein signaling modulator 2
GPX5 glutathione peroxidase 5
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRID2 glutamate receptor, ionotropic, delta 2
GSPT1 G1 to S phase transition 1
GUCY2F guanylate cyclase 2F, retinal
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HDAC9 histone deacetylase 9
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2
HMBOX1 homeobox containing 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HOOK3 hook microtubule-tethering protein 3
HSF2BP heat shock transcription factor 2 binding protein
HSPA13 heat shock protein 70kDa family, member 13
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IFNA14 interferon, alpha 14
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
INTS2 integrator complex subunit 2
INVS inversin
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KAZN kazrin, periplakin interacting protein
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KDM1B lysine (K)-specific demethylase 1B
KDM4E lysine (K)-specific demethylase 4E
KIAA0586 KIAA0586
KIAA1143 KIAA1143
KIAA1644 KIAA1644
KIAA2018 KIAA2018
KIAA2026 KIAA2026
KIF13A kinesin family member 13A
KIF26B kinesin family member 26B
KIF2A kinesin heavy chain member 2A
KLF12 Kruppel-like factor 12
KLHL9 kelch-like family member 9
KMT2A lysine (K)-specific methyltransferase 2A
KPNA3 karyopherin alpha 3 (importin alpha 4)
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT37 keratin 37, type I
LACE1 lactation elevated 1
LCE1D late cornified envelope 1D
LDOC1L leucine zipper, down-regulated in cancer 1-like
LEPROTL1 leptin receptor overlapping transcript-like 1
LHFPL3 lipoma HMGIC fusion partner-like 3
LINC00472 long intergenic non-protein coding RNA 472
LINC01550 long intergenic non-protein coding RNA 1550
LMBR1 limb development membrane protein 1
LOC100133050 glucuronidase, beta pseudogene
LOC284788 uncharacterized LOC284788
LOC400940 uncharacterized LOC400940
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRP1B low density lipoprotein receptor-related protein 1B
LRRN1 leucine rich repeat neuronal 1
LRRTM3 leucine rich repeat transmembrane neuronal 3
LRRTM4 leucine rich repeat transmembrane neuronal 4
MAGEH1 melanoma antigen family H1
MAP2 microtubule-associated protein 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MARVELD3 MARVEL domain containing 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MDS2 myelodysplastic syndrome 2 translocation associated
MED13 mediator complex subunit 13
MESTIT1 MEST intronic transcript 1, antisense RNA
METTL6 methyltransferase like 6
MIA3 melanoma inhibitory activity family, member 3
MIB1 mindbomb E3 ubiquitin protein ligase 1
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMD2 monocyte to macrophage differentiation-associated 2
MMGT1 membrane magnesium transporter 1
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MSX2P1 msh homeobox 2 pseudogene 1
MYH15 myosin, heavy chain 15
MYO10 myosin X
MYOM1 myomesin 1
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NBEAL1 neurobeachin-like 1
NCAM2 neural cell adhesion molecule 2
NCKAP5 NCK-associated protein 5
NF1 neurofibromin 1
NLGN1 neuroligin 1
NLGN3 neuroligin 3
NLGN4Y neuroligin 4, Y-linked
NPAS3 neuronal PAS domain protein 3
NPFFR1 neuropeptide FF receptor 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP210 nucleoporin 210kDa
NXPE2 neurexophilin and PC-esterase domain family, member 2
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OR4M2 olfactory receptor, family 4, subfamily M, member 2
OR4N3P olfactory receptor, family 4, subfamily N, member 3 pseudogene
OR52B4 olfactory receptor, family 52, subfamily B, member 4 (gene/pseudogene)
OSBPL8 oxysterol binding protein-like 8
OTC ornithine carbamoyltransferase
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAGE4 P antigen family, member 4 (prostate associated)
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARD6G par-6 family cell polarity regulator gamma
PARP8 poly (ADP-ribose) polymerase family, member 8
PCDH20 protocadherin 20
PCDHA10 protocadherin alpha 10
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGB6 protocadherin gamma subfamily B, 6
PCDHGC3 protocadherin gamma subfamily C, 3
PCDHGC4 protocadherin gamma subfamily C, 4
PCNAP1 proliferating cell nuclear antigen pseudogene 1
PCNX pecanex homolog (Drosophila)
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDCL phosducin-like
PDZD2 PDZ domain containing 2
PDZD8 PDZ domain containing 8
PGAP1 post-GPI attachment to proteins 1
PGM3 phosphoglucomutase 3
PHAX phosphorylated adaptor for RNA export
PHIP pleckstrin homology domain interacting protein
PID1 phosphotyrosine interaction domain containing 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIKFYVE phosphoinositide kinase, FYVE finger containing
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP4R1 protein phosphatase 4, regulatory subunit 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKY protein kinase, Y-linked, pseudogene
PRO0611 PRO0611 protein
PROSER1 proline and serine rich 1
PRRC1 proline-rich coiled-coil 1
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRO protein tyrosine phosphatase, receptor type, O
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PUM2 pumilio RNA-binding family member 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PVRL3 poliovirus receptor-related 3
PWP1 PWP1 homolog (S. cerevisiae)
QSER1 glutamine and serine rich 1
RANBP17 RAN binding protein 17
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBBP9 retinoblastoma binding protein 9
RBM26 RNA binding motif protein 26
RBM41 RNA binding motif protein 41
RBSN rabenosyn, RAB effector
RGPD8 RANBP2-like and GRIP domain containing 8
RGR retinal G protein coupled receptor
RIC1 RAB6A GEF complex partner 1
RMI1 RecQ mediated genome instability 1
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RSF1 remodeling and spacing factor 1
RWDD2A RWD domain containing 2A
SAMD8 sterile alpha motif domain containing 8
SAP30L SAP30-like
SBF2 SET binding factor 2
SCAF11 SR-related CTD-associated factor 11
SCAMP1 secretory carrier membrane protein 1
SCARA5 scavenger receptor class A, member 5
SCD5 stearoyl-CoA desaturase 5
SDHAP2 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
SEC63 SEC63 homolog (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEPT2 septin 2
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SETBP1 SET binding protein 1
SH3RF1 SH3 domain containing ring finger 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHISA3 shisa family member 3
SHISA6 shisa family member 6
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SLAIN1 SLAIN motif family, member 1
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SLC35G1 solute carrier family 35, member G1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
SLITRK2 SLIT and NTRK-like family, member 2
SLMO2 slowmo homolog 2 (Drosophila)
SLX4IP SLX4 interacting protein
SMAD5 SMAD family member 5
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SNORA44 small nucleolar RNA, H/ACA box 44
SNTG1 syntrophin, gamma 1
SNX13 sorting nexin 13
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SOX1 SRY (sex determining region Y)-box 1
SPAG9 sperm associated antigen 9
SPANXB1 SPANX family, member B1
SPAST spastin
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPRY3 sprouty homolog 3 (Drosophila)
STAG1 stromal antigen 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STON1-GTF2A1L STON1-GTF2A1L readthrough
STRADB STE20-related kinase adaptor beta
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STX17 syntaxin 17
SUB1 SUB1 homolog (S. cerevisiae)
SUCO SUN domain containing ossification factor
SULF2 sulfatase 2
SYN3 synapsin III
SYNJ2BP synaptojanin 2 binding protein
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TAOK1 TAO kinase 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCL1B T-cell leukemia/lymphoma 1B
TLX1NB TLX1 neighbor
TM9SF3 transmembrane 9 superfamily member 3
TMEM170A transmembrane protein 170A
TMEM257 transmembrane protein 257
TMEM263 transmembrane protein 263
TMLHE trimethyllysine hydroxylase, epsilon
TNN tenascin N
TNR tenascin R
TPR translocated promoter region, nuclear basket protein
TRAF3 TNF receptor-associated factor 3
TRIP11 thyroid hormone receptor interactor 11
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TSN translin
TSPAN11 tetraspanin 11
TTC3 tetratricopeptide repeat domain 3
TTC8 tetratricopeptide repeat domain 8
TTTY6B testis-specific transcript, Y-linked 6B (non-protein coding)
TUG1 taurine up-regulated 1 (non-protein coding)
TXNRD3NB thioredoxin reductase 3 neighbor
UBE2DNL ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene)
UBXN7 UBX domain protein 7
UEVLD UEV and lactate/malate dehyrogenase domains
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
USP10 ubiquitin specific peptidase 10
USP51 ubiquitin specific peptidase 51
VLDLR very low density lipoprotein receptor
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VRTN vertebrae development associated
VTI1A vesicle transport through interaction with t-SNAREs 1A
WDFY3-AS2 WDFY3 antisense RNA 2
WNK3 WNK lysine deficient protein kinase 3
XPO4 exportin 4
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YLPM1 YLP motif containing 1
ZAR1L zygote arrest 1-like
ZBTB20 zinc finger and BTB domain containing 20
ZBTB37 zinc finger and BTB domain containing 37
ZC3H13 zinc finger CCCH-type containing 13
ZC3H14 zinc finger CCCH-type containing 14
ZCCHC24 zinc finger, CCHC domain containing 24
ZCWPW2 zinc finger, CW type with PWWP domain 2
ZEB2 zinc finger E-box binding homeobox 2
ZIM2 zinc finger, imprinted 2
ZMAT3 zinc finger, matrin-type 3
ZMYM2 zinc finger, MYM-type 2
ZNF24 zinc finger protein 24
ZNF257 zinc finger protein 257
ZNF534 zinc finger protein 534
ZNF555 zinc finger protein 555
ZNF608 zinc finger protein 608
ZNF624 zinc finger protein 624
ZNF658 zinc finger protein 658
ZNF681 zinc finger protein 681
ZNF778 zinc finger protein 778
ZNF81 zinc finger protein 81
ZNF99 zinc finger protein 99

low expression

Symbol Name
ALKBH5 AlkB family member 5, RNA demethylase
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
EMC10 ER membrane protein complex subunit 10
EMC4 ER membrane protein complex subunit 4
FAM103A1 family with sequence similarity 103, member A1
FAM219B family with sequence similarity 219, member B
IPW imprinted in Prader-Willi syndrome (non-protein coding)
MORF4L1 mortality factor 4 like 1
MTFMT mitochondrial methionyl-tRNA formyltransferase
NDN necdin, melanoma antigen (MAGE) family member
NDNL2 necdin-like 2
OAZ2 ornithine decarboxylase antizyme 2
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PAQR7 progestin and adipoQ receptor family member VII
PDCD7 programmed cell death 7
RPUSD2 RNA pseudouridylate synthase domain containing 2
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4
SNRPN small nuclear ribonucleoprotein polypeptide N
TMEM62 transmembrane protein 62
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZFAND6 zinc finger, AN1-type domain 6