Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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388 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL2 arylacetamide deacetylase-like 2
AADACL4 arylacetamide deacetylase-like 4
ABHD17C abhydrolase domain containing 17C
ACAD8 acyl-CoA dehydrogenase family, member 8
ACP1 acid phosphatase 1, soluble
ACSM5 acyl-CoA synthetase medium-chain family member 5
ACSS1 acyl-CoA synthetase short-chain family member 1
ACYP2 acylphosphatase 2, muscle type
ADGRB1 adhesion G protein-coupled receptor B1
ADGRF1 adhesion G protein-coupled receptor F1
ADI1 acireductone dioxygenase 1
AGFG2 ArfGAP with FG repeats 2
AGMO alkylglycerol monooxygenase
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C4 aldo-keto reductase family 1, member C4
AKR1C6P aldo-keto reductase family 1, member C6, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ALG1L ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMY2A amylase, alpha 2A (pancreatic)
ANAPC16 anaphase promoting complex subunit 16
ANGPTL1 angiopoietin-like 1
ANKRD37 ankyrin repeat domain 37
ANXA8L1 annexin A8-like 1
AP1M2 adaptor-related protein complex 1, mu 2 subunit
ARHGAP8 Rho GTPase activating protein 8
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARRB1 arrestin, beta 1
ASB15 ankyrin repeat and SOCS box containing 15
ATP13A5 ATPase type 13A5
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BID BH3 interacting domain death agonist
BMP15 bone morphogenetic protein 15
BOLL boule-like RNA-binding protein
BTNL8 butyrophilin-like 8
C10ORF120 chromosome 10 open reading frame 120
C11ORF53 chromosome 11 open reading frame 53
C12ORF29 chromosome 12 open reading frame 29
C12ORF54 chromosome 12 open reading frame 54
C14ORF105 chromosome 14 open reading frame 105
C17ORF104 chromosome 17 open reading frame 104
C1ORF116 chromosome 1 open reading frame 116
C1ORF52 chromosome 1 open reading frame 52
C1ORF94 chromosome 1 open reading frame 94
C1QBP complement component 1, q subcomponent binding protein
C20ORF197 chromosome 20 open reading frame 197
C2ORF78 chromosome 2 open reading frame 78
C3ORF79 chromosome 3 open reading frame 79
C4ORF33 chromosome 4 open reading frame 33
C5ORF38 chromosome 5 open reading frame 38
C6ORF52 chromosome 6 open reading frame 52
C7ORF71 chromosome 7 open reading frame 71
C9ORF152 chromosome 9 open reading frame 152
CABLES1 Cdk5 and Abl enzyme substrate 1
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CCBL2 cysteine conjugate-beta lyase 2
CCDC105 coiled-coil domain containing 105
CCDC116 coiled-coil domain containing 116
CCDC157 coiled-coil domain containing 157
CCND3 cyclin D3
CD9 CD9 molecule
CDC16 cell division cycle 16
CEACAM18 carcinoembryonic antigen-related cell adhesion molecule 18
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CERS1 ceramide synthase 1
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli)
CLDN4 claudin 4
CLDN6 claudin 6
CMC2 C-x(9)-C motif containing 2
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
COL23A1 collagen, type XXIII, alpha 1
COLCA1 colorectal cancer associated 1
COLCA2 colorectal cancer associated 2
COX7B2 cytochrome c oxidase subunit VIIb2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRISP3 cysteine-rich secretory protein 3
CSDC2 cold shock domain containing C2, RNA binding
CSTL1 cystatin-like 1
CT45A2 cancer/testis antigen family 45, member A2
CT45A5 cancer/testis antigen family 45, member A5
CTNNBIP1 catenin, beta interacting protein 1
CTNND2 catenin (cadherin-associated protein), delta 2
CTSE cathepsin E
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAAM2 dishevelled associated activator of morphogenesis 2
DAGLA diacylglycerol lipase, alpha
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEXI Dexi homolog (mouse)
DLD dihydrolipoamide dehydrogenase
DNMBP-AS1 DNMBP antisense RNA 1
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
E2F6 E2F transcription factor 6
EHD1 EH-domain containing 1
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERN2 endoplasmic reticulum to nucleus signaling 2
ESX1 ESX homeobox 1
ETFA electron-transfer-flavoprotein, alpha polypeptide
EZR ezrin
FADS2 fatty acid desaturase 2
FAM118A family with sequence similarity 118, member A
FAM182B family with sequence similarity 182, member B
FAM185A family with sequence similarity 185, member A
FAM200A family with sequence similarity 200, member A
FAM213A family with sequence similarity 213, member A
FAM43B family with sequence similarity 43, member B
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXW10 F-box and WD repeat domain containing 10
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLJ16779 uncharacterized LOC100192386
FLJ42393 uncharacterized LOC401105
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATSL3 GATS protein-like 3
GBP7 guanylate binding protein 7
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GEMIN8 gem (nuclear organelle) associated protein 8
GGT6 gamma-glutamyltransferase 6
GINS3 GINS complex subunit 3 (Psf3 homolog)
GK2 glycerol kinase 2
GLB1L2 galactosidase, beta 1-like 2
GLB1L3 galactosidase, beta 1-like 3
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GOLGA7B golgin A7 family, member B
GPM6B glycoprotein M6B
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GUCA1B guanylate cyclase activator 1B (retina)
GYPA glycophorin A (MNS blood group)
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HBZ hemoglobin, zeta
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HGC6.3 uncharacterized LOC100128124
HMGB3P1 high mobility group box 3 pseudogene 1
HMOX2 heme oxygenase 2
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HRSP12 heat-responsive protein 12
HSBP1L1 heat shock factor binding protein 1-like 1
HSPB2 heat shock 27kDa protein 2
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNL2 interferon, lambda 2
IL31 interleukin 31
IL9 interleukin 9
ILDR1 immunoglobulin-like domain containing receptor 1
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IQCF1 IQ motif containing F1
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGB6 integrin, beta 6
IVD isovaleryl-CoA dehydrogenase
KAAG1 kidney associated antigen 1
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD11 potassium channel tetramerization domain containing 11
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLB klotho beta
KLHDC8B kelch domain containing 8B
KLK10 kallikrein-related peptidase 10
KRT17 keratin 17, type I
KRT19 keratin 19, type I
KRT7 keratin 7, type II
KRTAP5-7 keratin associated protein 5-7
KRTAP9-4 keratin associated protein 9-4
LAD1 ladinin 1
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LINC00521 long intergenic non-protein coding RNA 521
LINC00588 long intergenic non-protein coding RNA 588
LRWD1 leucine-rich repeats and WD repeat domain containing 1
LURAP1L leucine rich adaptor protein 1-like
LUZP4 leucine zipper protein 4
LYPD2 LY6/PLAUR domain containing 2
MAGED1 melanoma antigen family D1
MAGED4B melanoma antigen family D4B
MARVELD3 MARVEL domain containing 3
MC4R melanocortin 4 receptor
MED31 mediator complex subunit 31
METTL9 methyltransferase like 9
MROH8 maestro heat-like repeat family member 8
MRPS28 mitochondrial ribosomal protein S28
MT1G metallothionein 1G
MTCH1 mitochondrial carrier 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MUC13 mucin 13, cell surface associated
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBPC1 myosin binding protein C, slow type
MYEOV2 myeloma overexpressed 2
MYLK4 myosin light chain kinase family, member 4
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NBAS neuroblastoma amplified sequence
NFS1 NFS1 cysteine desulfurase
NKAIN4 Na+/K+ transporting ATPase interacting 4
NOD2 nucleotide-binding oligomerization domain containing 2
NPHP4 nephronophthisis 4
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1
NTSR2 neurotensin receptor 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUTM2A NUT family member 2A
OARD1 O-acyl-ADP-ribose deacylase 1
OLMALINC oligodendrocyte maturation-associated long intergenic non-coding RNA
OR10A2 olfactory receptor, family 10, subfamily A, member 2
OR10A3 olfactory receptor, family 10, subfamily A, member 3
OR2A2 olfactory receptor, family 2, subfamily A, member 2
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR2T10 olfactory receptor, family 2, subfamily T, member 10
OR4K5 olfactory receptor, family 4, subfamily K, member 5
OR52A4P olfactory receptor, family 52, subfamily A, member 4, pseudogene
OR5K2 olfactory receptor, family 5, subfamily K, member 2
OSBPL2 oxysterol binding protein-like 2
PAGE4 P antigen family, member 4 (prostate associated)
PALM paralemmin
PARK7 parkinson protein 7
PASD1 PAS domain containing 1
PC pyruvate carboxylase
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDHGA2 protocadherin gamma subfamily A, 2
PDAP1 PDGFA associated protein 1
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDZD9 PDZ domain containing 9
PEBP1 phosphatidylethanolamine binding protein 1
PEBP4 phosphatidylethanolamine-binding protein 4
PEX11G peroxisomal biogenesis factor 11 gamma
PGA3 pepsinogen 3, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1
PIGR polymeric immunoglobulin receptor
PINK1 PTEN induced putative kinase 1
PLIN1 perilipin 1
PMPCB peptidase (mitochondrial processing) beta
PNPLA8 patatin-like phospholipase domain containing 8
POF1B premature ovarian failure, 1B
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
PON1 paraoxonase 1
PON2 paraoxonase 2
POR P450 (cytochrome) oxidoreductase
PPIAL4C peptidylprolyl isomerase A (cyclophilin A)-like 4C
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PQLC1 PQ loop repeat containing 1
PRAMEF10 PRAME family member 10
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRM1 protamine 1
PRSS22 protease, serine, 22
PRSS35 protease, serine, 35
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PTCD1 pentatricopeptide repeat domain 1
PTTG2 pituitary tumor-transforming 2
RAB41 RAB41, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RASA4 RAS p21 protein activator 4
RASL12 RAS-like, family 12
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RAVER2 ribonucleoprotein, PTB-binding 2
RFC5 replication factor C (activator 1) 5, 36.5kDa
RFPL4B ret finger protein-like 4B
RGAG1 retrotransposon gag domain containing 1
RGCC regulator of cell cycle
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RHEB Ras homolog enriched in brain
RINT1 RAD50 interactor 1
RND2 Rho family GTPase 2
S100A14 S100 calcium binding protein A14
S100P S100 calcium binding protein P
S1PR1 sphingosine-1-phosphate receptor 1
SCARNA15 small Cajal body-specific RNA 15
SCGB2A2 secretoglobin, family 2A, member 2
SCRG1 stimulator of chondrogenesis 1
SELL selectin L
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERF1A small EDRK-rich factor 1A (telomeric)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SH2B2 SH2B adaptor protein 2
SH2D1B SH2 domain containing 1B
SH2D6 SH2 domain containing 6
SH3YL1 SH3 and SYLF domain containing 1
SHCBP1L SHC SH2-domain binding protein 1-like
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SLC12A9 solute carrier family 12, member 9
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC25A18 solute carrier family 25 (glutamate carrier), member 18
SLC25A41 solute carrier family 25, member 41
SLC35E4 solute carrier family 35, member E4
SLC39A11 solute carrier family 39, member 11
SLC44A4 solute carrier family 44, member 4
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLURP1 secreted LY6/PLAUR domain containing 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNHG7 small nucleolar RNA host gene 7
SNN stannin
SNORA11E small nucleolar RNA, H/ACA box 11E
SNORA38 small nucleolar RNA, H/ACA box 38
SNORA40 small nucleolar RNA, H/ACA box 40
SNORA65 small nucleolar RNA, H/ACA box 65
SNORA71B small nucleolar RNA, H/ACA box 71B
SNORA76C small nucleolar RNA, H/ACA box 76C
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPANXN4 SPANX family, member N4
SPHAR S-phase response (cyclin related)
SPINK5 serine peptidase inhibitor, Kazal type 5
SRRT serrate, RNA effector molecule
SSX6 synovial sarcoma, X breakpoint 6 (pseudogene)
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST5 suppression of tumorigenicity 5
ST7-AS2 ST7 antisense RNA 2
STK16 serine/threonine kinase 16
STON2 stonin 2
STX18 syntaxin 18
SYCP3 synaptonemal complex protein 3
SYPL1 synaptophysin-like 1
TAAR6 trace amine associated receptor 6
TAS2R41 taste receptor, type 2, member 41
TG thyroglobulin
TGM6 transglutaminase 6
THRA thyroid hormone receptor, alpha
TIMP4 TIMP metallopeptidase inhibitor 4
TM4SF4 transmembrane 4 L six family member 4
TMEM95 transmembrane protein 95
TMPRSS4 transmembrane protease, serine 4
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TPRKB TP53RK binding protein
TPST2 tyrosylprotein sulfotransferase 2
TRAF3IP2 TRAF3 interacting protein 2
TRAPPC12 trafficking protein particle complex 12
TRIM16L tripartite motif containing 16-like
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TSHB thyroid stimulating hormone, beta
TSPAN1 tetraspanin 1
TSPAN33 tetraspanin 33
TSSC1 tumor suppressing subtransferable candidate 1
TST thiosulfate sulfurtransferase (rhodanese)
TXNDC17 thioredoxin domain containing 17
TXNL4A thioredoxin-like 4A
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UFSP1 UFM1-specific peptidase 1 (non-functional)
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UPP2 uridine phosphorylase 2
USH1C Usher syndrome 1C (autosomal recessive, severe)
USP2 ubiquitin specific peptidase 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR45B WD repeat domain 45B
WDR5B WD repeat domain 5B
WFDC2 WAP four-disulfide core domain 2
WISP2 WNT1 inducible signaling pathway protein 2
YAF2 YY1 associated factor 2
ZC3HC1 zinc finger, C3HC-type containing 1
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF225 zinc finger protein 225
ZNF277 zinc finger protein 277
ZNF385A zinc finger protein 385A
ZNF630 zinc finger protein 630
ZNF668 zinc finger protein 668
ZNHIT1 zinc finger, HIT-type containing 1

low expression

Symbol Name
GABPA GA binding protein transcription factor, alpha subunit 60kDa
LTN1 listerin E3 ubiquitin protein ligase 1
MRPL35 mitochondrial ribosomal protein L35
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
RWDD2B RWD domain containing 2B
SCAF4 SR-related CTD-associated factor 4
SEC23IP SEC23 interacting protein
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZDHHC6 zinc finger, DHHC-type containing 6
ZNF594 zinc finger protein 594