Brain Lower Grade Glioma_LGG_TCGA-FG-5965-01B-11R-1896-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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350 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-FG-5965-01B-11R-1896-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL3 arylacetamide deacetylase-like 3
ABLIM1 actin binding LIM protein 1
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGRB1 adhesion G protein-coupled receptor B1
ADGRF4 adhesion G protein-coupled receptor F4
ADGRG3 adhesion G protein-coupled receptor G3
AGO1 argonaute RISC catalytic component 1
AHSP alpha hemoglobin stabilizing protein
AIRE autoimmune regulator
AKAP3 A kinase (PRKA) anchor protein 3
AKAP6 A kinase (PRKA) anchor protein 6
ALAS2 5'-aminolevulinate synthase 2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANGPT4 angiopoietin 4
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD31 ankyrin repeat domain 31
ANKRD6 ankyrin repeat domain 6
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
AQP4 aquaporin 4
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGAP42 Rho GTPase activating protein 42
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASB3 ankyrin repeat and SOCS box containing 3
ATF7 activating transcription factor 7
ATF7IP activating transcription factor 7 interacting protein
ATP1A1-AS1 ATP1A1 antisense RNA 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BEND2 BEN domain containing 2
BTG2 BTG family, member 2
C10ORF120 chromosome 10 open reading frame 120
C11ORF52 chromosome 11 open reading frame 52
C14ORF105 chromosome 14 open reading frame 105
C14ORF37 chromosome 14 open reading frame 37
C17ORF47 chromosome 17 open reading frame 47
C17ORF77 chromosome 17 open reading frame 77
C17ORF99 chromosome 17 open reading frame 99
C1ORF106 chromosome 1 open reading frame 106
C1ORF94 chromosome 1 open reading frame 94
C2ORF42 chromosome 2 open reading frame 42
C3ORF22 chromosome 3 open reading frame 22
C3ORF58 chromosome 3 open reading frame 58
C4ORF17 chromosome 4 open reading frame 17
C6ORF25 chromosome 6 open reading frame 25
C6ORF89 chromosome 6 open reading frame 89
C7ORF66 chromosome 7 open reading frame 66
CA1 carbonic anhydrase I
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CCBL2 cysteine conjugate-beta lyase 2
CCDC38 coiled-coil domain containing 38
CD38 CD38 molecule
CD69 CD69 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH20 cadherin 20, type 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CEP350 centrosomal protein 350kDa
CGB8 chorionic gonadotropin, beta polypeptide 8
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLCN3 chloride channel, voltage-sensitive 3
CLEC4D C-type lectin domain family 4, member D
CMTM2 CKLF-like MARVEL transmembrane domain containing 2
COLCA2 colorectal cancer associated 2
CPT2 carnitine palmitoyltransferase 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSDC2 cold shock domain containing C2, RNA binding
CSF1 colony stimulating factor 1 (macrophage)
CSRNP1 cysteine-serine-rich nuclear protein 1
CST9 cystatin 9 (testatin)
CTBP2 C-terminal binding protein 2
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DAPK1 death-associated protein kinase 1
DCAF12 DDB1 and CUL4 associated factor 12
DDR1 discoidin domain receptor tyrosine kinase 1
DEFA1B defensin, alpha 1B
DEFB125 defensin, beta 125
DIS3L DIS3 like exosome 3'-5' exoribonuclease
DLG5 discs, large homolog 5 (Drosophila)
DNAH7 dynein, axonemal, heavy chain 7
DUSP1 dual specificity phosphatase 1
DUXA double homeobox A
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EGR1 early growth response 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EPB42 erythrocyte membrane protein band 4.2
ESRG embryonic stem cell related (non-protein coding)
EVA1A eva-1 homolog A (C. elegans)
EYA1 EYA transcriptional coactivator and phosphatase 1
EZR ezrin
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FAM188B family with sequence similarity 188, member B
FBXL22 F-box and leucine-rich repeat protein 22
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FFAR2 free fatty acid receptor 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXO3B forkhead box O3B pseudogene
FRMD3 FERM domain containing 3
FRMD5 FERM domain containing 5
FTO fat mass and obesity associated
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GATA5 GATA binding protein 5
GATSL2 GATS protein-like 2
GLG1 golgi glycoprotein 1
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPKOW G patch domain and KOW motifs
GPM6B glycoprotein M6B
GPR119 G protein-coupled receptor 119
GPR75 G protein-coupled receptor 75
GRAP2 GRB2-related adaptor protein 2
GRHL3 grainyhead-like 3 (Drosophila)
GTF2IRD2B GTF2I repeat domain containing 2B
GYPB glycophorin B (MNS blood group)
HAL histidine ammonia-lyase
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HBD hemoglobin, delta
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HBM hemoglobin, mu
HCAR2 hydroxycarboxylic acid receptor 2
HCAR3 hydroxycarboxylic acid receptor 3
HCG22 HLA complex group 22
HEATR5A HEAT repeat containing 5A
HEMGN hemogen
HES1 hes family bHLH transcription factor 1
HMBOX1 homeobox containing 1
HSPB2 heat shock 27kDa protein 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B
IFNA5 interferon, alpha 5
IFNK interferon, kappa
IL17A interleukin 17A
IL18R1 interleukin 18 receptor 1
IL1R2 interleukin 1 receptor, type II
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KIAA0355 KIAA0355
KIAA0754 KIAA0754
KIAA1147 KIAA1147
KIF1B kinesin family member 1B
KLF4 Kruppel-like factor 4 (gut)
KLHL36 kelch-like family member 36
KLHL8 kelch-like family member 8
KRT23 keratin 23, type I
KRTAP10-2 keratin associated protein 10-2
KRTAP9-2 keratin associated protein 9-2
KRTAP9-4 keratin associated protein 9-4
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LHFPL1 lipoma HMGIC fusion partner-like 1
LINC01550 long intergenic non-protein coding RNA 1550
LIPG lipase, endothelial
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC646813 DEAH (Asp-Glu-Ala-His) box helicase 9 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP1B low density lipoprotein receptor-related protein 1B
LRRC17 leucine rich repeat containing 17
LRRC3 leucine rich repeat containing 3
LRRC3B leucine rich repeat containing 3B
LRRN3 leucine rich repeat neuronal 3
LTBP4 latent transforming growth factor beta binding protein 4
LY6G6F lymphocyte antigen 6 complex, locus G6F
MACF1 microtubule-actin crosslinking factor 1
MARVELD3 MARVEL domain containing 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCL1 myeloid cell leukemia 1
MEFV Mediterranean fever
METTL9 methyltransferase like 9
MEX3C mex-3 RNA binding family member C
MGA MGA, MAX dimerization protein
MGAM maltase-glucoamylase
MGC16025 uncharacterized LOC85009
MGC16275 uncharacterized protein MGC16275
MKL1 megakaryoblastic leukemia (translocation) 1
MKRN3 makorin ring finger protein 3
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMP8 matrix metallopeptidase 8
MSI2 musashi RNA-binding protein 2
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAV1 neuron navigator 1
NCKAP5 NCK-associated protein 5
NCOA1 nuclear receptor coactivator 1
NF1 neurofibromin 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFE2 nuclear factor, erythroid 2
NFIA nuclear factor I/A
NHLRC2 NHL repeat containing 2
NHSL1 NHS-like 1
NKAIN3 Na+/K+ transporting ATPase interacting 3
NKX2-6 NK2 homeobox 6
NLGN4X neuroligin 4, X-linked
NPHP4 nephronophthisis 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRADDP neurotrophin receptor associated death domain, pseudogene
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OCLN occludin
OR13C9 olfactory receptor, family 13, subfamily C, member 9
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR4F5 olfactory receptor, family 4, subfamily F, member 5
OR4K2 olfactory receptor, family 4, subfamily K, member 2
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR52B4 olfactory receptor, family 52, subfamily B, member 4 (gene/pseudogene)
OR6K3 olfactory receptor, family 6, subfamily K, member 3
OR6N1 olfactory receptor, family 6, subfamily N, member 1
OR6V1 olfactory receptor, family 6, subfamily V, member 1
OR8B8 olfactory receptor, family 8, subfamily B, member 8
PARD3B par-3 family cell polarity regulator beta
PCDHA5 protocadherin alpha 5
PCDHA8 protocadherin alpha 8
PCDHGB2 protocadherin gamma subfamily B, 2
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDZD8 PDZ domain containing 8
PF4 platelet factor 4
PF4V1 platelet factor 4 variant 1
PGLYRP1 peptidoglycan recognition protein 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHOSPHO1 phosphatase, orphan 1
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1
PKDREJ polycystin (PKD) family receptor for egg jelly
PKNOX1 PBX/knotted 1 homeobox 1
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
PLXNC1 plexin C1
PON2 paraoxonase 2
POU2F1 POU class 2 homeobox 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRDM11 PR domain containing 11
PRR34 proline rich 34
PRX periaxin
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRG protein tyrosine phosphatase, receptor type, G
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFX4 regulatory factor X, 4 (influences HLA class II expression)
RGAG1 retrotransposon gag domain containing 1
S100A12 S100 calcium binding protein A12
S100P S100 calcium binding protein P
S1PR1 sphingosine-1-phosphate receptor 1
SCGB2B2 secretoglobin, family 2B, member 2
SCHIP1 schwannomin interacting protein 1
SDPR serum deprivation response
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
SETBP1 SET binding protein 1
SGPL1 sphingosine-1-phosphate lyase 1
SIRPB1 signal-regulatory protein beta 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC35E4 solute carrier family 35, member E4
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLITRK1 SLIT and NTRK-like family, member 1
SMAD7 SMAD family member 7
SMAD9 SMAD family member 9
SMG6 SMG6 nonsense mediated mRNA decay factor
SNCAIP synuclein, alpha interacting protein
SNN stannin
SNORA15 small nucleolar RNA, H/ACA box 15
SNORD116-4 small nucleolar RNA, C/D box 116-4
SNX27 sorting nexin family member 27
SPANXB1 SPANX family, member B1
SPATA2 spermatogenesis associated 2
SPEN spen family transcriptional repressor
SPINK5 serine peptidase inhibitor, Kazal type 5
SRL sarcalumenin
STAG1 stromal antigen 1
STPG2 sperm-tail PG-rich repeat containing 2
SUPT20HL2 suppressor of Ty 20 homolog (S. cerevisiae)-like 2
TAAR2 trace amine associated receptor 2
TAAR5 trace amine associated receptor 5
TACR1 tachykinin receptor 1
TCP10L2 t-complex 10-like 2
TECTB tectorin beta
TFDP3 transcription factor Dp family, member 3
TIGD2 tigger transposable element derived 2
TIMP3 TIMP metallopeptidase inhibitor 3
TJP1 tight junction protein 1
TMEM244 transmembrane protein 244
TMEM254 transmembrane protein 254
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNIK TRAF2 and NCK interacting kinase
TNNI1 troponin I type 1 (skeletal, slow)
TNS3 tensin 3
TPRXL tetra-peptide repeat homeobox-like
TPST2 tyrosylprotein sulfotransferase 2
TREML2 triggering receptor expressed on myeloid cells-like 2
TREML3P triggering receptor expressed on myeloid cells-like 3, pseudogene
TRIM42 tripartite motif containing 42
TRRAP transformation/transcription domain-associated protein
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTC28 tetratricopeptide repeat domain 28
TXNIP thioredoxin interacting protein
UBIAD1 UbiA prenyltransferase domain containing 1
UBL4B ubiquitin-like 4B
USP26 ubiquitin specific peptidase 26
USP9X ubiquitin specific peptidase 9, X-linked
VEPH1 ventricular zone expressed PH domain-containing 1
VGLL4 vestigial-like family member 4
VNN3 vanin 3
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WBP1L WW domain binding protein 1-like
WDR31 WD repeat domain 31
WDR88 WD repeat domain 88
WEE2 WEE1 homolog 2 (S. pombe)
WIPF2 WAS/WASL interacting protein family, member 2
WNT3 wingless-type MMTV integration site family, member 3
ZBED3 zinc finger, BED-type containing 3
ZBTB20 zinc finger and BTB domain containing 20
ZFHX4 zinc finger homeobox 4
ZFP36 ZFP36 ring finger protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZFX zinc finger protein, X-linked
ZHX3 zinc fingers and homeoboxes 3
ZNF275 zinc finger protein 275
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF425 zinc finger protein 425
ZNF429 zinc finger protein 429
ZNF77 zinc finger protein 77
ZNF774 zinc finger protein 774
ZNF792 zinc finger protein 792
ZNF844 zinc finger protein 844

low expression

Symbol Name
BRD9 bromodomain containing 9
C11ORF58 chromosome 11 open reading frame 58
CCDC127 coiled-coil domain containing 127
DENR density-regulated protein
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
FAR1 fatty acyl CoA reductase 1
LIN7C lin-7 homolog C (C. elegans)
METTL15 methyltransferase like 15
PAIP1 poly(A) binding protein interacting protein 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
SMIM15 small integral membrane protein 15
STRAP serine/threonine kinase receptor associated protein