Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

411 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ADGRG7 adhesion G protein-coupled receptor G7
ADIPOR2 adiponectin receptor 2
ADORA3 adenosine A3 receptor
AHCYL1 adenosylhomocysteinase-like 1
AIDA axin interactor, dorsalization associated
AK3 adenylate kinase 3
AKAP3 A kinase (PRKA) anchor protein 3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPT4 angiopoietin 4
ANKRD46 ankyrin repeat domain 46
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOC1P1 apolipoprotein C-I pseudogene 1
APOL4 apolipoprotein L, 4
ARHGAP15 Rho GTPase activating protein 15
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL11 ADP-ribosylation factor-like 11
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARRB2 arrestin, beta 2
ASB15 ankyrin repeat and SOCS box containing 15
ASB3 ankyrin repeat and SOCS box containing 3
ATP9A ATPase, class II, type 9A
AXL AXL receptor tyrosine kinase
BAG3 BCL2-associated athanogene 3
BCAS3 breast carcinoma amplified sequence 3
BHLHE41 basic helix-loop-helix family, member e41
BTK Bruton agammaglobulinemia tyrosine kinase
C10ORF128 chromosome 10 open reading frame 128
C10ORF54 chromosome 10 open reading frame 54
C11ORF52 chromosome 11 open reading frame 52
C12ORF74 chromosome 12 open reading frame 74
C15ORF43 chromosome 15 open reading frame 43
C17ORF98 chromosome 17 open reading frame 98
C19ORF38 chromosome 19 open reading frame 38
C1ORF162 chromosome 1 open reading frame 162
C3AR1 complement component 3a receptor 1
CAB39L calcium binding protein 39-like
CALCOCO2 calcium binding and coiled-coil domain 2
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CARD11 caspase recruitment domain family, member 11
CASC2 cancer susceptibility candidate 2 (non-protein coding)
CCRL2 chemokine (C-C motif) receptor-like 2
CD37 CD37 molecule
CD53 CD53 molecule
CD84 CD84 molecule
CD86 CD86 molecule
CD99 CD99 molecule
CDK15 cyclin-dependent kinase 15
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHP2 calcineurin-like EF-hand protein 2
CLDN18 claudin 18
CLDND1 claudin domain containing 1
CLEC9A C-type lectin domain family 9, member A
CNPY3 canopy FGF signaling regulator 3
CPED1 cadherin-like and PC-esterase domain containing 1
CPVL carboxypeptidase, vitellogenic-like
CREBL2 cAMP responsive element binding protein-like 2
CREG1 cellular repressor of E1A-stimulated genes 1
CSF1R colony stimulating factor 1 receptor
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTNND2 catenin (cadherin-associated protein), delta 2
CXCL16 chemokine (C-X-C motif) ligand 16
CXCR4 chemokine (C-X-C motif) receptor 4
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DEFA6 defensin, alpha 6, Paneth cell-specific
DERA deoxyribose-phosphate aldolase (putative)
DERL1 derlin 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNASE2B deoxyribonuclease II beta
DOCK8 dedicator of cytokinesis 8
DRAM2 DNA-damage regulated autophagy modulator 2
DTNA dystrobrevin, alpha
DUOXA1 dual oxidase maturation factor 1
DUSP27 dual specificity phosphatase 27 (putative)
DYM dymeclin
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EBI3 Epstein-Barr virus induced 3
ECHDC3 enoyl CoA hydratase domain containing 3
EDARADD EDAR-associated death domain
EFHD1 EF-hand domain family, member D1
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3IP1 eukaryotic translation initiation factor 3, subunit I pseudogene 1
EIF5B eukaryotic translation initiation factor 5B
ENY2 enhancer of yellow 2 homolog (Drosophila)
EVI2A ecotropic viral integration site 2A
EVI2B ecotropic viral integration site 2B
EXT1 exostosin glycosyltransferase 1
FAM101A family with sequence similarity 101, member A
FAM105A family with sequence similarity 105, member A
FAM107A family with sequence similarity 107, member A
FAM129B family with sequence similarity 129, member B
FAM159A family with sequence similarity 159, member A
FAM19A4 family with sequence similarity 19 (chemokine (C-C motif)-like), member A4
FAM212A family with sequence similarity 212, member A
FAM229B family with sequence similarity 229, member B
FAM3B family with sequence similarity 3, member B
FAM49B family with sequence similarity 49, member B
FAM58BP cyclin-related protein FAM58B
FAM71D family with sequence similarity 71, member D
FAXDC2 fatty acid hydroxylase domain containing 2
FBXO31 F-box protein 31
FBXO32 F-box protein 32
FBXO8 F-box protein 8
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FFAR4 free fatty acid receptor 4
FGF20 fibroblast growth factor 20
FLJ44635 TPT1-like protein
FNTA farnesyltransferase, CAAX box, alpha
FOXO4 forkhead box O4
FRG2B FSHD region gene 2 family, member B
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
GABARAPL2 GABA(A) receptor-associated protein-like 2
GBX2 gastrulation brain homeobox 2
GDI2 GDP dissociation inhibitor 2
GFAP glial fibrillary acidic protein
GHRL ghrelin/obestatin prepropeptide
GIMAP4 GTPase, IMAP family member 4
GLRX glutaredoxin (thioltransferase)
GMFB glia maturation factor, beta
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPN3 GPN-loop GTPase 3
GPR183 G protein-coupled receptor 183
GPR34 G protein-coupled receptor 34
GPSM3 G-protein signaling modulator 3
GPX1 glutathione peroxidase 1
GTF2A1L general transcription factor IIA, 1-like
GTF2H5 general transcription factor IIH, polypeptide 5
GUCA2B guanylate cyclase activator 2B (uroguanylin)
GYPC glycophorin C (Gerbich blood group)
HAPLN2 hyaluronan and proteoglycan link protein 2
HAUS4 HAUS augmin-like complex, subunit 4
HAVCR2 hepatitis A virus cellular receptor 2
HCLS1 hematopoietic cell-specific Lyn substrate 1
HHEX hematopoietically expressed homeobox
HMOX2 heme oxygenase 2
HNMT histamine N-methyltransferase
HPR haptoglobin-related protein
HPSE heparanase
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSP90B3P heat shock protein 90kDa beta (Grp94), member 3, pseudogene
IFNGR1 interferon gamma receptor 1
IFNLR1 interferon, lambda receptor 1
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1
IL13RA1 interleukin 13 receptor, alpha 1
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IPO11 importin 11
IRF8 interferon regulatory factor 8
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNK13 potassium channel, two pore domain subfamily K, member 13
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIAA0196 KIAA0196
KIAA2013 KIAA2013
KIF1C kinesin family member 1C
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KRT33A keratin 33A, type I
KRTAP11-1 keratin associated protein 11-1
LAPTM5 lysosomal protein transmembrane 5
LASP1 LIM and SH3 protein 1
LAT2 linker for activation of T cells family, member 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LGALS9 lectin, galactoside-binding, soluble, 9
LHFPL2 lipoma HMGIC fusion partner-like 2
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LINC00310 long intergenic non-protein coding RNA 310
LINC00323 long intergenic non-protein coding RNA 323
LINC00324 long intergenic non-protein coding RNA 324
LMBRD1 LMBR1 domain containing 1
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC100132831 A20-binding inhibitor of NF-kappaB activation 2 pseudogene
LOC284441 actin-related protein 2 pseudogene
LOC286094
LOC400043 uncharacterized LOC400043
LOC494141 solute carrier family 25, member 51 pseudogene
LOC646813 DEAH (Asp-Glu-Ala-His) box helicase 9 pseudogene
LOC649330
LOC727924 uncharacterized LOC727924
LPAR5 lysophosphatidic acid receptor 5
LPCAT2 lysophosphatidylcholine acyltransferase 2
LPL lipoprotein lipase
LPXN leupaxin
LY86 lymphocyte antigen 86
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAF1 MAF1 homolog (S. cerevisiae)
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MAP4 microtubule-associated protein 4
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MED30 mediator complex subunit 30
MED31 mediator complex subunit 31
MEP1A meprin A, alpha (PABA peptide hydrolase)
MERTK MER proto-oncogene, tyrosine kinase
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIA2 melanoma inhibitory activity 2
MORC1 MORC family CW-type zinc finger 1
MPC2 mitochondrial pyruvate carrier 2
MRC1 mannose receptor, C type 1
MSTN myostatin
MTDH metadherin
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
MYBPC1 myosin binding protein C, slow type
MYOT myotilin
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAPSB napsin B aspartic peptidase, pseudogene
NCF2 neutrophil cytosolic factor 2
NCK2 NCK adaptor protein 2
NCKAP1L NCK-associated protein 1-like
NDRG1 N-myc downstream regulated 1
NFE2L1 nuclear factor, erythroid 2-like 1
NINJ1 ninjurin 1
NKX2-8 NK2 homeobox 8
NLRP9 NLR family, pyrin domain containing 9
NRROS negative regulator of reactive oxygen species
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NUDCD1 NudC domain containing 1
NUDT16P1 nudix (nucleoside diphosphate linked moiety X)-type motif 16 pseudogene 1
ODF1 outer dense fiber of sperm tails 1
OLFML3 olfactomedin-like 3
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR4N4 olfactory receptor, family 4, subfamily N, member 4
OR52A4P olfactory receptor, family 52, subfamily A, member 4, pseudogene
OR52E2 olfactory receptor, family 52, subfamily E, member 2
OTC ornithine carbamoyltransferase
OTOP1 otopetrin 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PA2G4P4 proliferation-associated 2G4 pseudogene 4
PABPC1 poly(A) binding protein, cytoplasmic 1
PABPC1P2 poly(A) binding protein, cytoplasmic 1 pseudogene 2
PABPC3 poly(A) binding protein, cytoplasmic 3
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PARD3 par-3 family cell polarity regulator
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHGA9 protocadherin gamma subfamily A, 9
PCDHGB5 protocadherin gamma subfamily B, 5
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDGFB platelet-derived growth factor beta polypeptide
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLD4 phospholipase D family, member 4
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLGLA plasminogen-like A (pseudogene)
PLIN3 perilipin 3
PLXDC2 plexin domain containing 2
PMCHL2 pro-melanin-concentrating hormone-like 2, pseudogene
PNRC1 proline-rich nuclear receptor coactivator 1
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POTEE POTE ankyrin domain family, member E
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
POU1F1 POU class 1 homeobox 1
PPIAL4D peptidylprolyl isomerase A (cyclophilin A)-like 4D
PPT1 palmitoyl-protein thioesterase 1
PRKX protein kinase, X-linked
PROSC proline synthetase co-transcribed homolog (bacterial)
PRR5L proline rich 5 like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTTG1IP pituitary tumor-transforming 1 interacting protein
PYCARD PYD and CARD domain containing
RAB10 RAB10, member RAS oncogene family
RAB13 RAB13, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAD21 RAD21 homolog (S. pombe)
RANBP3L RAN binding protein 3-like
RAP1A RAP1A, member of RAS oncogene family
RASGRP4 RAS guanyl releasing protein 4
RASL11A RAS-like, family 11, member A
RCSD1 RCSD domain containing 1
RGS1 regulator of G-protein signaling 1
RGS10 regulator of G-protein signaling 10
RGS19 regulator of G-protein signaling 19
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOA ras homolog family member A
RNASE6 ribonuclease, RNase A family, k6
RNASET2 ribonuclease T2
RND2 Rho family GTPase 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF13 ring finger protein 13
RNF130 ring finger protein 130
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL13AP20 ribosomal protein L13a pseudogene 20
RPL13AP6 ribosomal protein L13a pseudogene 6
RPL19P12 ribosomal protein L19 pseudogene 12
RPL30 ribosomal protein L30
RPS26P11 ribosomal protein S26 pseudogene 11
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RTP2 receptor (chemosensory) transporter protein 2
SAMD4A sterile alpha motif domain containing 4A
SAP18 Sin3A-associated protein, 18kDa
SASH3 SAM and SH3 domain containing 3
SCARNA9L small Cajal body-specific RNA 9-like
SCCPDH saccharopine dehydrogenase (putative)
SCIMP SLP adaptor and CSK interacting membrane protein
SELL selectin L
SELPLG selectin P ligand
SEPP1 selenoprotein P, plasma, 1
SFR1 SWI5-dependent recombination repair 1
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC8 sialic acid binding Ig-like lectin 8
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRPB2 signal-regulatory protein beta 2
SIRPD signal-regulatory protein delta
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SMAP2 small ArfGAP2
SNAI3 snail family zinc finger 3
SNORA45A small nucleolar RNA, H/ACA box 45A
SNX24 sorting nexin 24
SORBS1 sorbin and SH3 domain containing 1
SOWAHD sosondowah ankyrin repeat domain family member D
SPN sialophorin
SPP1 secreted phosphoprotein 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
STIM1 stromal interaction molecule 1
STX12 syntaxin 12
SYK spleen tyrosine kinase
SYTL4 synaptotagmin-like 4
TAAR5 trace amine associated receptor 5
TATDN1 TatD DNase domain containing 1
TBXAS1 thromboxane A synthase 1 (platelet)
TCEB3C transcription elongation factor B polypeptide 3C (elongin A3)
TECRL trans-2,3-enoyl-CoA reductase-like
TGFB1 transforming growth factor, beta 1
TIMP4 TIMP metallopeptidase inhibitor 4
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TMEM119 transmembrane protein 119
TMEM144 transmembrane protein 144
TMEM156 transmembrane protein 156
TMEM52B transmembrane protein 52B
TMEM86A transmembrane protein 86A
TMIGD2 transmembrane and immunoglobulin domain containing 2
TMOD1 tropomodulin 1
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TNK1 tyrosine kinase, non-receptor, 1
TOR4A torsin family 4, member A
TPI1P3 triosephosphate isomerase 1 pseudogene 3
TPT1 tumor protein, translationally-controlled 1
TRAK2 trafficking protein, kinesin binding 2
TREM2 triggering receptor expressed on myeloid cells 2
TSPAN14 tetraspanin 14
UBC ubiquitin C
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
VSIG4 V-set and immunoglobulin domain containing 4
VWA5A von Willebrand factor A domain containing 5A
WASF2 WAS protein family, member 2
WBP11P1 WW domain binding protein 11 pseudogene 1
WBSCR27 Williams Beuren syndrome chromosome region 27
WDYHV1 WDYHV motif containing 1
ZDHHC20 zinc finger, DHHC-type containing 20
ZNF16 zinc finger protein 16
ZNF641 zinc finger protein 641
ZNF706 zinc finger protein 706

low expression

Symbol Name
AP3D1 adaptor-related protein complex 3, delta 1 subunit
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CUL9 cullin 9
DZIP1 DAZ interacting zinc finger protein 1
FOXK2 forkhead box K2
GRAMD4 GRAM domain containing 4
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MTX3 metaxin 3
NEURL4 neuralized E3 ubiquitin protein ligase 4
PCNXL3 pecanex-like 3 (Drosophila)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PRDM15 PR domain containing 15
REV1 REV1, polymerase (DNA directed)
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SUGP2 SURP and G patch domain containing 2
TTPAL tocopherol (alpha) transfer protein-like
XPO6 exportin 6
ZNF335 zinc finger protein 335
ZNF512B zinc finger protein 512B
ZNF557 zinc finger protein 557
ZSWIM1 zinc finger, SWIM-type containing 1