Brain Lower Grade Glioma_LGG_TCGA-DU-6407-01A-13R-1708-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

415 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-6407-01A-13R-1708-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACPP acid phosphatase, prostate
ADAM17 ADAM metallopeptidase domain 17
ADCY8 adenylate cyclase 8 (brain)
ADD1 adducin 1 (alpha)
ADGRF3 adhesion G protein-coupled receptor F3
AGO1 argonaute RISC catalytic component 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMOTL2 angiomotin like 2
ANKRD46 ankyrin repeat domain 46
ANO2 anoctamin 2, calcium activated chloride channel
ANTXR1 anthrax toxin receptor 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP35 Rho GTPase activating protein 35
ARMC1 armadillo repeat containing 1
ASCL1 achaete-scute family bHLH transcription factor 1
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAG4 BCL2-associated athanogene 4
BANP BTG3 associated nuclear protein
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAN brevican
BCDIN3D BCDIN3 domain containing
BPI bactericidal/permeability-increasing protein
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C1ORF116 chromosome 1 open reading frame 116
C1ORF185 chromosome 1 open reading frame 185
C1ORF94 chromosome 1 open reading frame 94
C21ORF33 chromosome 21 open reading frame 33
C2ORF44 chromosome 2 open reading frame 44
C8ORF31 chromosome 8 open reading frame 31
C8ORF33 chromosome 8 open reading frame 33
CARD18 caspase recruitment domain family, member 18
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CCAR2 cell cycle and apoptosis regulator 2
CCDC97 coiled-coil domain containing 97
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHMP7 charged multivesicular body protein 7
CLIP2 CAP-GLY domain containing linker protein 2
CLUAP1 clusterin associated protein 1
CNOT4 CCR4-NOT transcription complex, subunit 4
CNOT6L CCR4-NOT transcription complex, subunit 6-like
CNOT7 CCR4-NOT transcription complex, subunit 7
CPNE3 copine III
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CTCF CCCTC-binding factor (zinc finger protein)
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNND1 catenin (cadherin-associated protein), delta 1
CTNND2 catenin (cadherin-associated protein), delta 2
DCAF7 DDB1 and CUL4 associated factor 7
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DERL1 derlin 1
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DLL3 delta-like 3 (Drosophila)
DNAAF5 dynein, axonemal, assembly factor 5
DPP6 dipeptidyl-peptidase 6
DSCR3 Down syndrome critical region 3
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
E2F5 E2F transcription factor 5, p130-binding
EEF2 eukaryotic translation elongation factor 2
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4H eukaryotic translation initiation factor 4H
ELMO1 engulfment and cell motility 1
ELP3 elongator acetyltransferase complex subunit 3
ERLIN2 ER lipid raft associated 2
ERO1LB ERO1-like beta (S. cerevisiae)
ESRG embryonic stem cell related (non-protein coding)
EXOC4 exocyst complex component 4
FAM110B family with sequence similarity 110, member B
FAM182A family with sequence similarity 182, member A
FAM193A family with sequence similarity 193, member A
FAM200A family with sequence similarity 200, member A
FAM220A family with sequence similarity 220, member A
FAM66A family with sequence similarity 66, member A
FAM84B family with sequence similarity 84, member B
FAM9B family with sequence similarity 9, member B
FBXO21 F-box protein 21
FHL1 four and a half LIM domains 1
FIBIN fin bud initiation factor homolog (zebrafish)
FLG filaggrin
FMO2 flavin containing monooxygenase 2 (non-functional)
FNTA farnesyltransferase, CAAX box, alpha
FOXK1 forkhead box K1
FOXP2 forkhead box P2
FSD2 fibronectin type III and SPRY domain containing 2
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
GAB1 GRB2-associated binding protein 1
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GATSL2 GATS protein-like 2
GCC1 GRIP and coiled-coil domain containing 1
GLTPD2 glycolipid transfer protein domain containing 2
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GOLIM4 golgi integral membrane protein 4
GPR137B G protein-coupled receptor 137B
GRIK4 glutamate receptor, ionotropic, kainate 4
GSC goosecoid homeobox
GSR glutathione reductase
GTF2IP1 general transcription factor IIi pseudogene 1
GTF2IRD2B GTF2I repeat domain containing 2B
H2AFV H2A histone family, member V
HEATR5A HEAT repeat containing 5A
HIP1 huntingtin interacting protein 1
HIPK2 homeodomain interacting protein kinase 2
HIRA histone cell cycle regulator
HM13 histocompatibility (minor) 13
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HOXA13 homeobox A13
HPS6 Hermansky-Pudlak syndrome 6
HRNR hornerin
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA8 heat shock 70kDa protein 8
HTT huntingtin
IFT140 intraflagellar transport 140
IL17RD interleukin 17 receptor D
IMPAD1 inositol monophosphatase domain containing 1
INTS9 integrator complex subunit 9
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JAM2 junctional adhesion molecule 2
KAT6A K(lysine) acetyltransferase 6A
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCTD20 potassium channel tetramerization domain containing 20
KHDC1 KH homology domain containing 1
KIAA0196 KIAA0196
KIAA1429 KIAA1429
KIAA1549 KIAA1549
KIF26A kinesin family member 26A
KLK2 kallikrein-related peptidase 2
KLK4 kallikrein-related peptidase 4
KRT35 keratin 35, type I
KRTAP10-2 keratin associated protein 10-2
KRTAP4-4 keratin associated protein 4-4
LAPTM4B lysosomal protein transmembrane 4 beta
LDAH lipid droplet associated hydrolase
LDOC1L leucine zipper, down-regulated in cancer 1-like
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LIMCH1 LIM and calponin homology domains 1
LINC00304 long intergenic non-protein coding RNA 304
LOC642852 uncharacterized LOC642852
LOC646999 akirin 1 pseudogene
LPIN1 lipin 1
LRRC14 leucine rich repeat containing 14
LRRC3 leucine rich repeat containing 3
LUZP6 leucine zipper protein 6
LY6K lymphocyte antigen 6 complex, locus K
MAML2 mastermind-like 2 (Drosophila)
MBOAT2 membrane bound O-acyltransferase domain containing 2
MEIG1 meiosis/spermiogenesis associated 1
MEPCE methylphosphate capping enzyme
METAP2 methionyl aminopeptidase 2
MEX3A mex-3 RNA binding family member A
MIEF1 mitochondrial elongation factor 1
MKRN1 makorin ring finger protein 1
MMP20 matrix metallopeptidase 20
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MSMB microseminoprotein, beta-
MSTN myostatin
MTDH metadherin
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH10 myosin, heavy chain 10, non-muscle
NBAS neuroblastoma amplified sequence
NBN nibrin
NCOA5 nuclear receptor coactivator 5
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NELFA negative elongation factor complex member A
NES nestin
NFIA nuclear factor I/A
NFIB nuclear factor I/B
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NKAIN3 Na+/K+ transporting ATPase interacting 3
NOBOX NOBOX oogenesis homeobox
NOL10 nucleolar protein 10
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOTCH2 notch 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRIP1 nuclear receptor interacting protein 1
OR13G1 olfactory receptor, family 13, subfamily G, member 1
OR5T1 olfactory receptor, family 5, subfamily T, member 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PABPC3 poly(A) binding protein, cytoplasmic 3
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PBX1 pre-B-cell leukemia homeobox 1
PCA3 prostate cancer associated 3 (non-protein coding)
PCDH10 protocadherin 10
PCDHA3 protocadherin alpha 3
PCDHB5 protocadherin beta 5
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGA12 protocadherin gamma subfamily A, 12
PDZRN3 PDZ domain containing ring finger 3
PKNOX1 PBX/knotted 1 homeobox 1
PLD6 phospholipase D family, member 6
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POM121C POM121 transmembrane nucleoporin C
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT2 protein arginine methyltransferase 2
PROSC proline synthetase co-transcribed homolog (bacterial)
PRR12 proline rich 12
PRR23C proline rich 23C
PTCD1 pentatricopeptide repeat domain 1
PTK2 protein tyrosine kinase 2
PTTG1IP pituitary tumor-transforming 1 interacting protein
PUM1 pumilio RNA-binding family member 1
PUM2 pumilio RNA-binding family member 2
PURB purine-rich element binding protein B
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB2A RAB2A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD21 RAD21 homolog (S. pombe)
RAD21L1 RAD21-like 1 (S. pombe)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RBKS ribokinase
RBM27 RNA binding motif protein 27
REG4 regenerating islet-derived family, member 4
REPIN1 replication initiator 1
RFTN2 raftlin family member 2
RHOA ras homolog family member A
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIPK4 receptor-interacting serine-threonine kinase 4
RNF139 ring finger protein 139
RNF150 ring finger protein 150
RNF216 ring finger protein 216
RNF32 ring finger protein 32
RNF39 ring finger protein 39
RNF4 ring finger protein 4
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPL13AP17 ribosomal protein L13a pseudogene 17
RPL23AP53 ribosomal protein L23a pseudogene 53
RPL7 ribosomal protein L7
RRP1B ribosomal RNA processing 1B
RSBN1 round spermatid basic protein 1
RSBN1L round spermatid basic protein 1-like
SALL2 spalt-like transcription factor 2
SAMD13 sterile alpha motif domain containing 13
SAR1A secretion associated, Ras related GTPase 1A
SCAF4 SR-related CTD-associated factor 4
SCN4B sodium channel, voltage gated, type IV beta subunit
SCRIB scribbled planar cell polarity protein
SEBOX SEBOX homeobox
SEC1P secretory blood group 1, pseudogene
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SERBP1 SERPINE1 mRNA binding protein 1
SERINC5 serine incorporator 5
SF3B3 splicing factor 3b, subunit 3, 130kDa
SGK223 homolog of rat pragma of Rnd2
SKI SKI proto-oncogene
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC25A47 solute carrier family 25, member 47
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC44A4 solute carrier family 44, member 4
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLITRK6 SLIT and NTRK-like family, member 6
SMIM19 small integral membrane protein 19
SND1 staphylococcal nuclease and tudor domain containing 1
SNIP1 Smad nuclear interacting protein 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX15 SRY (sex determining region Y)-box 15
SPATA45 spermatogenesis associated 45
SPERT spermatid associated
SPESP1 sperm equatorial segment protein 1
SPIN4 spindlin family, member 4
SPON1 spondin 1, extracellular matrix protein
SPP2 secreted phosphoprotein 2, 24kDa
SPRR4 small proline-rich protein 4
STK17B serine/threonine kinase 17b
STYXL1 serine/threonine/tyrosine interacting-like 1
SUFU suppressor of fused homolog (Drosophila)
SULF2 sulfatase 2
SUMO3 small ubiquitin-like modifier 3
TBCEL tubulin folding cofactor E-like
TCAF1 TRPM8 channel-associated factor 1
TCEA1 transcription elongation factor A (SII), 1
TCF3 transcription factor 3
TCP10L t-complex 10-like
TGS1 trimethylguanosine synthase 1
THAP1 THAP domain containing, apoptosis associated protein 1
TIGD5 tigger transposable element derived 5
TLX1NB TLX1 neighbor
TMEM106B transmembrane protein 106B
TMEM170A transmembrane protein 170A
TMEM218 transmembrane protein 218
TMPRSS6 transmembrane protease, serine 6
TNIP2 TNFAIP3 interacting protein 2
TNPO3 transportin 3
TOX3 TOX high mobility group box family member 3
TPTEP1 transmembrane phosphatase with tensin homology pseudogene 1
TRIM35 tripartite motif containing 35
TRRAP transformation/transcription domain-associated protein
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TTC3 tetratricopeptide repeat domain 3
TTI2 TELO2 interacting protein 2
TTYH1 tweety family member 1
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBTD2 ubiquitin domain containing 2
UBXN2A UBX domain protein 2A
UBXN2B UBX domain protein 2B
UNC119B unc-119 homolog B (C. elegans)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP42 ubiquitin specific peptidase 42
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGLL4 vestigial-like family member 4
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae)
WASL Wiskott-Aldrich syndrome-like
WDFY3-AS2 WDFY3 antisense RNA 2
WDR35 WD repeat domain 35
WDR4 WD repeat domain 4
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
WNT5A wingless-type MMTV integration site family, member 5A
XPO7 exportin 7
YLPM1 YLP motif containing 1
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBTB10 zinc finger and BTB domain containing 10
ZBTB45 zinc finger and BTB domain containing 45
ZC3H3 zinc finger CCCH-type containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZDHHC2 zinc finger, DHHC-type containing 2
ZDHHC4 zinc finger, DHHC-type containing 4
ZFHX4 zinc finger homeobox 4
ZFYVE1 zinc finger, FYVE domain containing 1
ZHX1 zinc fingers and homeoboxes 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZMYM4 zinc finger, MYM-type 4
ZNF12 zinc finger protein 12
ZNF268 zinc finger protein 268
ZNF282 zinc finger protein 282
ZNF3 zinc finger protein 3
ZNF319 zinc finger protein 319
ZNF395 zinc finger protein 395
ZNF398 zinc finger protein 398
ZNF420 zinc finger protein 420
ZNF425 zinc finger protein 425
ZNF556 zinc finger protein 556
ZNF596 zinc finger protein 596
ZNF614 zinc finger protein 614
ZNF615 zinc finger protein 615
ZNF616 zinc finger protein 616
ZNF623 zinc finger protein 623
ZNF649 zinc finger protein 649
ZNF677 zinc finger protein 677
ZNF704 zinc finger protein 704
ZNF721 zinc finger protein 721
ZNF746 zinc finger protein 746
ZNF765 zinc finger protein 765
ZNF777 zinc finger protein 777
ZNF804A zinc finger protein 804A
ZNF813 zinc finger protein 813
ZNF827 zinc finger protein 827
ZNF835 zinc finger protein 835
ZNF843 zinc finger protein 843
ZNF853 zinc finger protein 853
ZSCAN20 zinc finger and SCAN domain containing 20
ZSCAN25 zinc finger and SCAN domain containing 25
ZZZ3 zinc finger, ZZ-type containing 3

low expression

Symbol Name
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
C18ORF8 chromosome 18 open reading frame 8
CAPN10 calpain 10
CCNL1 cyclin L1
CREBZF CREB/ATF bZIP transcription factor
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DUSP28 dual specificity phosphatase 28
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
GANC glucosidase, alpha; neutral C
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
KRBOX4 KRAB box domain containing 4
LOC728613 programmed cell death 6 pseudogene
LONP2 lon peptidase 2, peroxisomal
MCTS1 malignant T cell amplified sequence 1
MPPE1 metallophosphoesterase 1
MTERF4 mitochondrial transcription termination factor 4
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
PBX2 pre-B-cell leukemia homeobox 2
PCSK7 proprotein convertase subtilisin/kexin type 7
POLI polymerase (DNA directed) iota
PRPF4B pre-mRNA processing factor 4B
RBFA ribosome binding factor A (putative)
RNF214 ring finger protein 214
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SNRNP48 small nuclear ribonucleoprotein 48kDa (U11/U12)
SRSF5 serine/arginine-rich splicing factor 5
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMEM126A transmembrane protein 126A
TMEM126B transmembrane protein 126B
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
WDR11 WD repeat domain 11
WRNIP1 Werner helicase interacting protein 1
YTHDC2 YTH domain containing 2