Brain Lower Grade Glioma_LGG_TCGA-DH-A66B-01A-11R-A29R-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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Genes

377 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DH-A66B-01A-11R-A29R-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL4 arylacetamide deacetylase-like 4
ACTB actin, beta
ACTG1 actin gamma 1
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAM17 ADAM metallopeptidase domain 17
ADAM9 ADAM metallopeptidase domain 9
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADGRE1 adhesion G protein-coupled receptor E1
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
AIDA axin interactor, dorsalization associated
AJUBA ajuba LIM protein
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANO6 anoctamin 6
AP1AR adaptor-related protein complex 1 associated regulatory protein
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APIP APAF1 interacting protein
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARG2 arginase 2
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BAHD1 bromo adjacent homology domain containing 1
BAIAP2 BAI1-associated protein 2
BCKDK branched chain ketoacid dehydrogenase kinase
BIRC2 baculoviral IAP repeat containing 2
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BMPR1A bone morphogenetic protein receptor, type IA
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTBD3 BTB (POZ) domain containing 3
C15ORF52 chromosome 15 open reading frame 52
C16ORF62 chromosome 16 open reading frame 62
C16ORF72 chromosome 16 open reading frame 72
C1ORF198 chromosome 1 open reading frame 198
C1ORF226 chromosome 1 open reading frame 226
C1QL1 complement component 1, q subcomponent-like 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C20ORF141 chromosome 20 open reading frame 141
C4A complement component 4A (Rodgers blood group)
CAB39L calcium binding protein 39-like
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPN2 calpain 2, (m/II) large subunit
CARS cysteinyl-tRNA synthetase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC90B coiled-coil domain containing 90B
CCND1 cyclin D1
CCNY cyclin Y
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CD44 CD44 molecule (Indian blood group)
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CLEC4C C-type lectin domain family 4, member C
CLHC1 clathrin heavy chain linker domain containing 1
CLIC4 chloride intracellular channel 4
CNN2 calponin 2
CNN3 calponin 3, acidic
CNOT11 CCR4-NOT transcription complex, subunit 11
COMMD2 COMM domain containing 2
COX7B2 cytochrome c oxidase subunit VIIb2
CREBL2 cAMP responsive element binding protein-like 2
CRNKL1 crooked neck pre-mRNA splicing factor 1
CRYAB crystallin, alpha B
CTNND2 catenin (cadherin-associated protein), delta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYBB cytochrome b-245, beta polypeptide
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DAPK3 death-associated protein kinase 3
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DGKD diacylglycerol kinase, delta 130kDa
DHRS1 dehydrogenase/reductase (SDR family) member 1
DSG3 desmoglein 3
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DUXA double homeobox A
E2F6 E2F transcription factor 6
ECEL1 endothelin converting enzyme-like 1
EDNRA endothelin receptor type A
EEA1 early endosome antigen 1
ENAH enabled homolog (Drosophila)
FADD Fas (TNFRSF6)-associated via death domain
FAM134B family with sequence similarity 134, member B
FAM157B family with sequence similarity 157, member B
FAM21A family with sequence similarity 21, member A
FAM83A family with sequence similarity 83, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGBP Fc fragment of IgG binding protein
FCGR1C Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FERMT2 fermitin family member 2
FILIP1L filamin A interacting protein 1-like
FLJ41941 uncharacterized LOC100192420
FOPNL FGFR1OP N-terminal like
FOXR1 forkhead box R1
FRG2 FSHD region gene 2
FRMD5 FERM domain containing 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
FXR1 fragile X mental retardation, autosomal homolog 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GAS2L1 growth arrest-specific 2 like 1
GDAP2 ganglioside induced differentiation associated protein 2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIPC2 GIPC PDZ domain containing family, member 2
GLIS3 GLIS family zinc finger 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNPDA1 glucosamine-6-phosphate deaminase 1
GORAB golgin, RAB6-interacting
GPR65 G protein-coupled receptor 65
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
HAMP hepcidin antimicrobial peptide
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HDGF hepatoma-derived growth factor
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H3E histone cluster 1, H3e
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLX H2.0-like homeobox
HMGN4 high mobility group nucleosomal binding domain 4
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFT140 intraflagellar transport 140
IL21R interleukin 21 receptor
IL31RA interleukin 31 receptor A
ILK integrin-linked kinase
IPO9 importin 9
IQGAP2 IQ motif containing GTPase activating protein 2
IRF2BP2 interferon regulatory factor 2 binding protein 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB6 integrin, beta 6
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KRT13 keratin 13, type I
KRT16 keratin 16, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRTAP3-3 keratin associated protein 3-3
KRTAP4-9 keratin associated protein 4-9
LAPTM4A lysosomal protein transmembrane 4 alpha
LIN7C lin-7 homolog C (C. elegans)
LMAN2L lectin, mannose-binding 2-like
LMCD1 LIM and cysteine-rich domains 1
LOC285692 uncharacterized LOC285692
LOC644936 actin, beta pseudogene
LOC728392 uncharacterized LOC728392
LPAR6 lysophosphatidic acid receptor 6
LRRC19 leucine rich repeat containing 19
LRRN4CL LRRN4 C-terminal like
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
LSMEM2 leucine-rich single-pass membrane protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LY6D lymphocyte antigen 6 complex, locus D
LYST lysosomal trafficking regulator
MAEA macrophage erythroblast attacher
MAGEB3 melanoma antigen family B3
MAP3K7CL MAP3K7 C-terminal like
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MED24 mediator complex subunit 24
MED31 mediator complex subunit 31
MEF2A myocyte enhancer factor 2A
MFAP1 microfibrillar-associated protein 1
MFAP2 microfibrillar-associated protein 2
MICU2 mitochondrial calcium uptake 2
MKL1 megakaryoblastic leukemia (translocation) 1
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MORF4L1 mortality factor 4 like 1
MRGPRF MAS-related GPR, member F
MRPS10 mitochondrial ribosomal protein S10
MTMR11 myotubularin related protein 11
MUC1 mucin 1, cell surface associated
MUC21 mucin 21, cell surface associated
MVP major vault protein
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NAGLU N-acetylglucosaminidase, alpha
NFIL3 nuclear factor, interleukin 3 regulated
NMB neuromedin B
NMD3 NMD3 ribosome export adaptor
NME7 NME/NM23 family member 7
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOL10 nucleolar protein 10
NRBF2 nuclear receptor binding factor 2
NTN1 netrin 1
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUP188 nucleoporin 188kDa
OR13C9 olfactory receptor, family 13, subfamily C, member 9
OR1F1 olfactory receptor, family 1, subfamily F, member 1
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
OR1J2 olfactory receptor, family 1, subfamily J, member 2
OR1L4 olfactory receptor, family 1, subfamily L, member 4
OR2J3 olfactory receptor, family 2, subfamily J, member 3
OR52M1 olfactory receptor, family 52, subfamily M, member 1
OR6B1 olfactory receptor, family 6, subfamily B, member 1
ORAI3 ORAI calcium release-activated calcium modulator 3
OXSR1 oxidative stress responsive 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAIP1 poly(A) binding protein interacting protein 1
PAM peptidylglycine alpha-amidating monooxygenase
PARN poly(A)-specific ribonuclease
PCDHB8 protocadherin beta 8
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGLYRP4 peptidoglycan recognition protein 4
PHF13 PHD finger protein 13
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PNRC2 proline-rich nuclear receptor coactivator 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PPAP2A phosphatidic acid phosphatase type 2A
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PPP4C protein phosphatase 4, catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRR14 proline rich 14
PRRX1 paired related homeobox 1
PRSS22 protease, serine, 22
PRSS23 protease, serine, 23
PRTFDC1 phosphoribosyl transferase domain containing 1
PRUNE2 prune homolog 2 (Drosophila)
PSAP prosaposin
PSG4 pregnancy specific beta-1-glycoprotein 4
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PTCD2 pentatricopeptide repeat domain 2
PTTG1IP pituitary tumor-transforming 1 interacting protein
PXYLP1 2-phosphoxylose phosphatase 1
PYGB phosphorylase, glycogen; brain
RAB2B RAB2B, member RAS oncogene family
RB1 retinoblastoma 1
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RFTN1 raftlin, lipid raft linker 1
RGS21 regulator of G-protein signaling 21
RIN2 Ras and Rab interactor 2
RIPK2 receptor-interacting serine-threonine kinase 2
RNF19B ring finger protein 19B
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RNPEP arginyl aminopeptidase (aminopeptidase B)
RNPS1 RNA binding protein S1, serine-rich domain
RPA2 replication protein A2, 32kDa
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae)
RYK receptor-like tyrosine kinase
S100A3 S100 calcium binding protein A3
S100A6 S100 calcium binding protein A6
SEC11A SEC11 homolog A (S. cerevisiae)
SEP15 15 kDa selenoprotein
SERHL serine hydrolase-like (pseudogene)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SH3BP2 SH3-domain binding protein 2
SIGLECL1 SIGLEC family like 1
SLC10A7 solute carrier family 10, member 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A18 solute carrier family 22, member 18
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1
SMC5 structural maintenance of chromosomes 5
SMIM19 small integral membrane protein 19
SMNDC1 survival motor neuron domain containing 1
SMYD3 SET and MYND domain containing 3
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
SNW1 SNW domain containing 1
SNX16 sorting nexin 16
SNX17 sorting nexin 17
SPATA12 spermatogenesis associated 12
SPATA5L1 spermatogenesis associated 5-like 1
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPRR1A small proline-rich protein 1A
SPRR2C small proline-rich protein 2C (pseudogene)
SPRR3 small proline-rich protein 3
SPTSSB serine palmitoyltransferase, small subunit B
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STK40 serine/threonine kinase 40
SUMF1 sulfatase modifying factor 1
SYF2 SYF2 pre-mRNA-splicing factor
SYNDIG1 synapse differentiation inducing 1
SYTL2 synaptotagmin-like 2
TACSTD2 tumor-associated calcium signal transducer 2
TASP1 taspase, threonine aspartase, 1
TBC1D23 TBC1 domain family, member 23
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBXA2R thromboxane A2 receptor
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TEX36 testis expressed 36
TFAMP1 transcription factor A, mitochondrial pseudogene 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLE3 transducin-like enhancer of split 3
TLR10 toll-like receptor 10
TLR9 toll-like receptor 9
TM9SF1 transmembrane 9 superfamily member 1
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM107 transmembrane protein 107
TMEM167B transmembrane protein 167B
TMEM229B transmembrane protein 229B
TMEM43 transmembrane protein 43
TMOD1 tropomodulin 1
TMPRSS11B transmembrane protease, serine 11B
TMPRSS11D transmembrane protease, serine 11D
TMX1 thioredoxin-related transmembrane protein 1
TNIP2 TNFAIP3 interacting protein 2
TPST2 tyrosylprotein sulfotransferase 2
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TSSK6 testis-specific serine kinase 6
TTC23 tetratricopeptide repeat domain 23
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2I ubiquitin-conjugating enzyme E2I
UPP1 uridine phosphorylase 1
UTF1 undifferentiated embryonic cell transcription factor 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VCL vinculin
VENTX VENT homeobox
VGLL4 vestigial-like family member 4
VIM vimentin
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WBSCR17 Williams-Beuren syndrome chromosome region 17
WDR1 WD repeat domain 1
WLS wntless Wnt ligand secretion mediator
WNT2 wingless-type MMTV integration site family member 2
WNT5A wingless-type MMTV integration site family, member 5A
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YME1L1 YME1-like 1 ATPase
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZMPSTE24 zinc metallopeptidase STE24
ZNF267 zinc finger protein 267
ZNF410 zinc finger protein 410
ZNF487 zinc finger protein 487
ZNF747 zinc finger protein 747
ZNF768 zinc finger protein 768

low expression

Symbol Name
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
CXORF40B chromosome X open reading frame 40B
CXORF56 chromosome X open reading frame 56
DHRS4-AS1 DHRS4 antisense RNA 1
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
FXN frataxin
GTDC1 glycosyltransferase-like domain containing 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICA1L islet cell autoantigen 1,69kDa-like
IWS1 IWS1 homolog (S. cerevisiae)
MLH3 mutL homolog 3
MRI1 methylthioribose-1-phosphate isomerase 1
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDZD11 PDZ domain containing 11
PECR peroxisomal trans-2-enoyl-CoA reductase
PGBD2 piggyBac transposable element derived 2
PORCN porcupine homolog (Drosophila)
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
SMIM8 small integral membrane protein 8
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM185A transmembrane protein 185A
UBA1 ubiquitin-like modifier activating enzyme 1
UBB ubiquitin B