Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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410 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL4 arylacetamide deacetylase-like 4
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABHD1 abhydrolase domain containing 1
ABHD17C abhydrolase domain containing 17C
ACKR3 atypical chemokine receptor 3
ACOXL acyl-CoA oxidase-like
ACRV1 acrosomal vesicle protein 1
ACTRT3 actin-related protein T3
ADCY8 adenylate cyclase 8 (brain)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADD3 adducin 3 (gamma)
ADRA2A adrenoceptor alpha 2A
AFF2 AF4/FMR2 family, member 2
AGK acylglycerol kinase
AGMO alkylglycerol monooxygenase
AHCYL2 adenosylhomocysteinase-like 2
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AKAP4 A kinase (PRKA) anchor protein 4
AKR1E2 aldo-keto reductase family 1, member E2
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
ALMS1P Alstrom syndrome 1 pseudogene
AMBRA1 autophagy/beclin-1 regulator 1
AMOT angiomotin
AMOTL1 angiomotin like 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APOH apolipoprotein H (beta-2-glycoprotein I)
APOM apolipoprotein M
AQP8 aquaporin 8
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARHGAP33 Rho GTPase activating protein 33
ARHGAP6 Rho GTPase activating protein 6
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARL14EP ADP-ribosylation factor-like 14 effector protein
ARSG arylsulfatase G
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG2A autophagy related 2A
B3GAT2 beta-1,3-glucuronyltransferase 2
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
BBS1 Bardet-Biedl syndrome 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BDNF-AS BDNF antisense RNA
BMP15 bone morphogenetic protein 15
BPIFA1 BPI fold containing family A, member 1
BRAT1 BRCA1-associated ATM activator 1
BTBD18 BTB (POZ) domain containing 18
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF131 chromosome 10 open reading frame 131
C11ORF53 chromosome 11 open reading frame 53
C11ORF54 chromosome 11 open reading frame 54
C17ORF78 chromosome 17 open reading frame 78
C1ORF94 chromosome 1 open reading frame 94
C2ORF57 chromosome 2 open reading frame 57
C3ORF58 chromosome 3 open reading frame 58
C7ORF60 chromosome 7 open reading frame 60
C7ORF61 chromosome 7 open reading frame 61
C8A complement component 8, alpha polypeptide
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNG6 calcium channel, voltage-dependent, gamma subunit 6
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC116 coiled-coil domain containing 116
CCDC160 coiled-coil domain containing 160
CCDC73 coiled-coil domain containing 73
CCDC85C coiled-coil domain containing 85C
CCDC87 coiled-coil domain containing 87
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CDHR3 cadherin-related family member 3
CEP128 centrosomal protein 128kDa
CERS3 ceramide synthase 3
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli)
CHRM4 cholinergic receptor, muscarinic 4
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLPSL2 colipase-like 2
CLRN1-AS1 CLRN1 antisense RNA 1
COLCA1 colorectal cancer associated 1
COLCA2 colorectal cancer associated 2
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CREBZF CREB/ATF bZIP transcription factor
CSMD1 CUB and Sushi multiple domains 1
CTH cystathionine gamma-lyase
CTNND2 catenin (cadherin-associated protein), delta 2
CUL5 cullin 5
CUX1 cut-like homeobox 1
CYB561A3 cytochrome b561 family, member A3
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1
DACH2 dachshund family transcription factor 2
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2
DCHS2 dachsous cadherin-related 2
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DERA deoxyribose-phosphate aldolase (putative)
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DKFZP779M0652 uncharacterized DKFZp779M0652
DKK4 dickkopf WNT signaling pathway inhibitor 4
DNAH7 dynein, axonemal, heavy chain 7
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EAF2 ELL associated factor 2
EDNRB endothelin receptor type B
ELP4 elongator acetyltransferase complex subunit 4
EMID1 EMI domain containing 1
EML6 echinoderm microtubule associated protein like 6
EPPK1 epiplakin 1
EYA1 EYA transcriptional coactivator and phosphatase 1
FABP2 fatty acid binding protein 2, intestinal
FADS1 fatty acid desaturase 1
FAM189A2 family with sequence similarity 189, member A2
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM47C family with sequence similarity 47, member C
FAM69A family with sequence similarity 69, member A
FAM92A1P2 family with sequence similarity 92, member A3
FBXL22 F-box and leucine-rich repeat protein 22
FBXL7 F-box and leucine-rich repeat protein 7
FDX1 ferredoxin 1
FDXACB1 ferredoxin-fold anticodon binding domain containing 1
FEZF2 FEZ family zinc finger 2
FHOD3 formin homology 2 domain containing 3
FIBIN fin bud initiation factor homolog (zebrafish)
FLJ41941 uncharacterized LOC100192420
FOXR1 forkhead box R1
FOXRED1 FAD-dependent oxidoreductase domain containing 1
FSHR follicle stimulating hormone receptor
FZD5 frizzled class receptor 5
FZD7 frizzled class receptor 7
G6PC glucose-6-phosphatase, catalytic subunit
GALR3 galanin receptor 3
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP7 guanylate binding protein 7
GJA1 gap junction protein, alpha 1, 43kDa
GP9 glycoprotein IX (platelet)
GPHN gephyrin
GPR135 G protein-coupled receptor 135
GPR137 G protein-coupled receptor 137
GPR151 G protein-coupled receptor 151
GPR152 G protein-coupled receptor 152
GPR21 G protein-coupled receptor 21
GPR25 G protein-coupled receptor 25
GRHL2 grainyhead-like 2 (Drosophila)
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRM1 glutamate receptor, metabotropic 1
GSG1 germ cell associated 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF2A1L general transcription factor IIA, 1-like
GTF2IRD2 GTF2I repeat domain containing 2
GTF2IRD2B GTF2I repeat domain containing 2B
GTF2IRD2P1 GTF2I repeat domain containing 2 pseudogene 1
GYPB glycophorin B (MNS blood group)
HCG22 HLA complex group 22
HEPACAM hepatic and glial cell adhesion molecule
HEPHL1 hephaestin-like 1
HEPN1 hepatocellular carcinoma, down-regulated 1
HERPUD2 HERPUD family member 2
HGFAC HGF activator
HIBADH 3-hydroxyisobutyrate dehydrogenase
HIST3H3 histone cluster 3, H3
HMCN1 hemicentin 1
HMGB3P1 high mobility group box 3 pseudogene 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTATSF1 HIV-1 Tat specific factor 1
HUS1B HUS1 checkpoint homolog b (S. pombe)
IFNL3 interferon, lambda 3
IGSF1 immunoglobulin superfamily, member 1
IGSF3 immunoglobulin superfamily, member 3
IL17C interleukin 17C
IL17RD interleukin 17 receptor D
IL5 interleukin 5
INTS1 integrator complex subunit 1
INTS5 integrator complex subunit 5
IQCE IQ motif containing E
ISPD isoprenoid synthase domain containing
KAT5 K(lysine) acetyltransferase 5
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNK4 potassium channel, two pore domain subfamily K, member 4
KCTD6 potassium channel tetramerization domain containing 6
KDM2A lysine (K)-specific demethylase 2A
KHDC1L KH homology domain containing 1-like
KLHDC1 kelch domain containing 1
KLHL35 kelch-like family member 35
KLHL8 kelch-like family member 8
KLK15 kallikrein-related peptidase 15
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRTAP5-8 keratin associated protein 5-8
LCE1D late cornified envelope 1D
LECT1 leukocyte cell derived chemotaxin 1
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX1 LIM homeobox 1
LIN7C lin-7 homolog C (C. elegans)
LINC00238 long intergenic non-protein coding RNA 238
LINC00469 long intergenic non-protein coding RNA 469
LMNTD1 lamin tail domain containing 1
LOC389705 chromosome 4 open reading frame 27 pseudogene
LOC400794 uncharacterized LOC400794
LOC646762 uncharacterized LOC646762
LOC650293 seven transmembrane helix receptor
LPIN1 lipin 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP1B low density lipoprotein receptor-related protein 1B
LRRC19 leucine rich repeat containing 19
LRRC24 leucine rich repeat containing 24
LRRC4B leucine rich repeat containing 4B
LUZP2 leucine zipper protein 2
LYPD1 LY6/PLAUR domain containing 1
LYPD6 LY6/PLAUR domain containing 6
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAGEA9B melanoma antigen family A9B
MBD3L5 methyl-CpG binding domain protein 3-like 5
MBIP MAP3K12 binding inhibitory protein 1
METTL15 methyltransferase like 15
MGAT4C MGAT4 family, member C
MIB2 mindbomb E3 ubiquitin protein ligase 2
MID1IP1 MID1 interacting protein 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MLNR motilin receptor
MMP28 matrix metallopeptidase 28
MPPED2 metallophosphoesterase domain containing 2
MROH8 maestro heat-like repeat family member 8
MROH9 maestro heat-like repeat family member 9
MRPL49 mitochondrial ribosomal protein L49
MSLNL mesothelin-like
MT1IP metallothionein 1I, pseudogene
MUS81 MUS81 structure-specific endonuclease subunit
MYOM1 myomesin 1
MYOZ2 myozenin 2
N4BP2L1 NEDD4 binding protein 2-like 1
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NADK2 NAD kinase 2, mitochondrial
NANOS2 nanos homolog 2 (Drosophila)
NCAM1 neural cell adhesion molecule 1
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NOX3 NADPH oxidase 3
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRROS negative regulator of reactive oxygen species
NRXN2 neurexin 2
NTSR2 neurotensin receptor 2
NXPH1 neurexophilin 1
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1
OR10W1 olfactory receptor, family 10, subfamily W, member 1
OR13D1 olfactory receptor, family 13, subfamily D, member 1
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OR52A4P olfactory receptor, family 52, subfamily A, member 4, pseudogene
OR52W1 olfactory receptor, family 52, subfamily W, member 1
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2
OXT oxytocin/neurophysin I prepropeptide
PACS1 phosphofurin acidic cluster sorting protein 1
PADI6 peptidyl arginine deiminase, type VI
PAH phenylalanine hydroxylase
PAX6 paired box 6
PAX8 paired box 8
PCDH11X protocadherin 11 X-linked
PCDH9 protocadherin 9
PCDHGB7 protocadherin gamma subfamily B, 7
PCNXL3 pecanex-like 3 (Drosophila)
PCSK4 proprotein convertase subtilisin/kexin type 4
PDLIM5 PDZ and LIM domain 5
PDZD3 PDZ domain containing 3
PEG10 paternally expressed 10
PER3 period circadian clock 3
PEX10 peroxisomal biogenesis factor 10
PEX6 peroxisomal biogenesis factor 6
PHF21A PHD finger protein 21A
PHGDH phosphoglycerate dehydrogenase
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PITX3 paired-like homeodomain 3
PLCH1 phospholipase C, eta 1
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3
POU4F1 POU class 4 homeobox 1
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKG2 protein kinase, cGMP-dependent, type II
PRLHR prolactin releasing hormone receptor
PRR15 proline rich 15
PRR32 proline rich 32
PRSS50 protease, serine, 50
PSAT1 phosphoserine aminotransferase 1
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PTCH2 patched 2
PTGR2 prostaglandin reductase 2
PTPMT1 protein tyrosine phosphatase, mitochondrial 1
RAB6C RAB6C, member RAS oncogene family
RAD51B RAD51 paralog B
RADIL Ras association and DIL domains
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RASA4CP RAS p21 protein activator 4C, pseudogene
RASL10B RAS-like, family 10, member B
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS12 regulator of G-protein signaling 12
RHCE Rh blood group, CcEe antigens
RHOBTB3 Rho-related BTB domain containing 3
RHPN1 rhophilin, Rho GTPase binding protein 1
RIMBP3 RIMS binding protein 3
RIMBP3C RIMS binding protein 3C
RNF222 ring finger protein 222
RNF32 ring finger protein 32
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RPL10L ribosomal protein L10-like
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RTN3 reticulon 3
RWDD3 RWD domain containing 3
SALL2 spalt-like transcription factor 2
SCN4B sodium channel, voltage gated, type IV beta subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCYL1 SCY1-like 1 (S. cerevisiae)
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SFRP2 secreted frizzled-related protein 2
SGCZ sarcoglycan, zeta
SGSM2 small G protein signaling modulator 2
SH2D7 SH2 domain containing 7
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLC25A47 solute carrier family 25, member 47
SLC25A53 solute carrier family 25, member 53
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SMTNL1 smoothelin-like 1
SNN stannin
SNX7 sorting nexin 7
SORD sorbitol dehydrogenase
SP2 Sp2 transcription factor
SPANXC SPANX family, member C
SPHK2 sphingosine kinase 2
SSTR1 somatostatin receptor 1
STOX1 storkhead box 1
STRIP2 striatin interacting protein 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYCP2 synaptonemal complex protein 2
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAAR5 trace amine associated receptor 5
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAS1R2 taste receptor, type 1, member 2
TCP11 t-complex 11, testis-specific
TECTB tectorin beta
TENM1 teneurin transmembrane protein 1
TEX30 testis expressed 30
TEX33 testis expressed 33
TEX40 testis expressed 40
TG thyroglobulin
THPO thrombopoietin
TIGD3 tigger transposable element derived 3
TKFC triokinase/FMN cyclase
TKTL2 transketolase-like 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR9 toll-like receptor 9
TMC1 transmembrane channel-like 1
TMEM105 transmembrane protein 105
TMEM133 transmembrane protein 133
TMEM135 transmembrane protein 135
TMEM138 transmembrane protein 138
TMEM229A transmembrane protein 229A
TMEM65 transmembrane protein 65
TNRC18 trinucleotide repeat containing 18
TRIL TLR4 interactor with leucine-rich repeats
TSKS testis-specific serine kinase substrate
TUBG2 tubulin, gamma 2
TUSC1 tumor suppressor candidate 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VGLL1 vestigial-like family member 1
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae)
VSIG10L V-set and immunoglobulin domain containing 10 like
WBP2NL WBP2 N-terminal like
WDR86 WD repeat domain 86
WDR87 WD repeat domain 87
WWC3 WWC family member 3
YIPF7 Yip1 domain family, member 7
ZAN zonadhesin (gene/pseudogene)
ZCCHC18 zinc finger, CCHC domain containing 18
ZDHHC1 zinc finger, DHHC-type containing 1
ZDHHC19 zinc finger, DHHC-type containing 19
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF212 zinc finger protein 212
ZNF213 zinc finger protein 213
ZNF408 zinc finger protein 408
ZNF425 zinc finger protein 425
ZNF503 zinc finger protein 503
ZNF521 zinc finger protein 521
ZNF574 zinc finger protein 574
ZNF703 zinc finger protein 703
ZNF777 zinc finger protein 777
ZNF853 zinc finger protein 853
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN1 zinc finger and SCAN domain containing 1

low expression

Symbol Name
ERICH1 glutamate-rich 1
FAN1 FANCD2/FANCI-associated nuclease 1
KLF13 Kruppel-like factor 13
THEM4 thioesterase superfamily member 4
TLDC1 TBC/LysM-associated domain containing 1