Body Weight Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. (Experimental Factor Ontology, EFO_0004338)
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Genes

216 genes associated with the trait Body Weight in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
FTO fat mass and obesity associated 1.7613
THSD7A thrombospondin, type I, domain containing 7A 1.1953
CCDC171 coiled-coil domain containing 171 1.06262
RAB28 RAB28, member RAS oncogene family 1.03665
NMUR2 neuromedin U receptor 2 1.01899
PAPD5 PAP associated domain containing 5 0.958073
KAZN kazrin, periplakin interacting protein 0.947589
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.932185
TMEM236 transmembrane protein 236 0.914031
SLC35A5 solute carrier family 35, member A5 0.907843
FLT1 fms-related tyrosine kinase 1 0.896256
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.892024
MCTP2 multiple C2 domains, transmembrane 2 0.872234
HDAC9 histone deacetylase 9 0.86999
WWOX WW domain containing oxidoreductase 0.864405
CALCR calcitonin receptor 0.863965
SH2B1 SH2B adaptor protein 1 0.862644
CNTNAP2 contactin associated protein-like 2 0.845694
BDNF-AS BDNF antisense RNA 0.807263
CPNE4 copine IV 0.80219
RIT2 Ras-like without CAAX 2 0.777379
CHD7 chromodomain helicase DNA binding protein 7 0.774152
FHIT fragile histidine triad 0.770646
PTPRM protein tyrosine phosphatase, receptor type, M 0.765648
SEC16B SEC16 homolog B (S. cerevisiae) 0.763999
GPR176 G protein-coupled receptor 176 0.762938
BPIFA3 BPI fold containing family A, member 3 0.760097
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.75886
ZCCHC6 zinc finger, CCHC domain containing 6 0.758218
PKP1 plakophilin 1 0.755441
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.750846
GRIK1 glutamate receptor, ionotropic, kainate 1 0.747458
MYO1B myosin IB 0.739205
DNAH6 dynein, axonemal, heavy chain 6 0.738164
ATXN7 ataxin 7 0.738086
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.735585
ASIC2 acid sensing (proton gated) ion channel 2 0.728755
LGALS3 lectin, galactoside-binding, soluble, 3 0.727259
GABPB1 GA binding protein transcription factor, beta subunit 1 0.723958
FGF14 fibroblast growth factor 14 0.720112
TPD52L1 tumor protein D52-like 1 0.707584
SPTSSB serine palmitoyltransferase, small subunit B 0.705532
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.700497
PAWR PRKC, apoptosis, WT1, regulator 0.699073
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.688721
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 0.655663
MOXD1 monooxygenase, DBH-like 1 0.653768
KIF18A kinesin family member 18A 0.650727
VWA8 von Willebrand factor A domain containing 8 0.637348
UVRAG UV radiation resistance associated 0.634731
SLC16A12 solute carrier family 16, member 12 0.627405
FAM172A family with sequence similarity 172, member A 0.622859
NBEA neurobeachin 0.621704
CMYA5 cardiomyopathy associated 5 0.616058
PZP pregnancy-zone protein 0.61483
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.613017
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.612995
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.612212
BDNF brain-derived neurotrophic factor 0.609816
SCAPER S-phase cyclin A-associated protein in the ER 0.606709
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.603761
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 0.600229
ARL15 ADP-ribosylation factor-like 15 0.598052
THSD7B thrombospondin, type I, domain containing 7B 0.588076
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.584421
BBX bobby sox homolog (Drosophila) 0.572976
SYT1 synaptotagmin I 0.567404
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.566533
PARK2 parkin RBR E3 ubiquitin protein ligase 0.554194
SFMBT1 Scm-like with four mbt domains 1 0.551131
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 0.548141
CFAP44 cilia and flagella associated protein 44 0.546104
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.539853
MYO3B myosin IIIB 0.526963
RBM19 RNA binding motif protein 19 0.51998
FRMD6 FERM domain containing 6 0.51102
ADGRV1 adhesion G protein-coupled receptor V1 0.509999
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.501454
ANAPC4 anaphase promoting complex subunit 4 0.50084
PTPRD protein tyrosine phosphatase, receptor type, D 0.477029
PCAT4 prostate cancer associated transcript 4 (non-protein coding) 0.476429
GDAP1 ganglioside induced differentiation associated protein 1 0.475912
CAPN13 calpain 13 0.47258
CEP120 centrosomal protein 120kDa 0.443956
LAMA2 laminin, alpha 2 0.438963
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.438061
PLCB4 phospholipase C, beta 4 0.436057
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 0.434223
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene 0.432853
GRM7 glutamate receptor, metabotropic 7 0.421914
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.416889
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.415275
IFI27L1 interferon, alpha-inducible protein 27-like 1 0.406869
CEP112 centrosomal protein 112kDa 0.406869
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.395705
ARHGAP15 Rho GTPase activating protein 15 0.378873
GS1-259H13.2 transmembrane protein 225-like 0.378873
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1 0.378873
BICD1 bicaudal D homolog 1 (Drosophila) 0.378873
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.363191
NPAS3 neuronal PAS domain protein 3 0.343893
IRS2 insulin receptor substrate 2 0.343092
TSPAN11 tetraspanin 11 0.34227
LPP LIM domain containing preferred translocation partner in lipoma 0.33862
MLIP muscular LMNA-interacting protein 0.333294
MDN1 MDN1, midasin homolog (yeast) 0.330308
LTBP1 latent transforming growth factor beta binding protein 1 0.328423
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.327766
TMEM117 transmembrane protein 117 0.326961
FAM178A family with sequence similarity 178, member A 0.32464
USP34 ubiquitin specific peptidase 34 0.320606
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.310838
ASTN1 astrotactin 1 0.309694
RGS8 regulator of G-protein signaling 8 0.303811
TRIM24 tripartite motif containing 24 0.29992
NRP1 neuropilin 1 0.297841
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.291519
NUP93 nucleoporin 93kDa 0.282567
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.265921
CDC7 cell division cycle 7 0.26553
KCMF1 potassium channel modulatory factor 1 0.265422
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.260727
GZF1 GDNF-inducible zinc finger protein 1 0.259732
EPS8L2 EPS8-like 2 0.258251
ADRA1A adrenoceptor alpha 1A 0.256456
C2ORF61 chromosome 2 open reading frame 61 0.254182
ERBB4 erb-b2 receptor tyrosine kinase 4 0.25304
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.251846
NRIP1 nuclear receptor interacting protein 1 0.250214
WLS wntless Wnt ligand secretion mediator 0.244175
MCTP1 multiple C2 domains, transmembrane 1 0.237422
CNTN3 contactin 3 (plasmacytoma associated) 0.234151
DMD dystrophin 0.231583
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.22185
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.215046
SCFD2 sec1 family domain containing 2 0.209767
NRG2 neuregulin 2 0.200221
EPAS1 endothelial PAS domain protein 1 0.199276
EHF ets homologous factor 0.194676
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.194145
THSD4 thrombospondin, type I, domain containing 4 0.193281
SPRN shadow of prion protein homolog (zebrafish) 0.192817
TMEM47 transmembrane protein 47 0.190507
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.188234
MYRF myelin regulatory factor 0.184569
TDRD5 tudor domain containing 5 0.177796
DLG2 discs, large homolog 2 (Drosophila) 0.176639
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.170089
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.165541
ATXN1 ataxin 1 0.163853
EXOC4 exocyst complex component 4 0.163039
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.163039
ZMIZ1 zinc finger, MIZ-type containing 1 0.161021
SPEF2 sperm flagellar 2 0.156311
PLSCR2 phospholipid scramblase 2 0.155145
UNC13C unc-13 homolog C (C. elegans) 0.154657
IL15 interleukin 15 0.153684
BNC2 basonuclin 2 0.153185
LINC-PINT long intergenic non-protein coding RNA, p53 induced transcript 0.152188
CENPM centromere protein M 0.150029
ZNF135 zinc finger protein 135 0.147349
TGM1 transglutaminase 1 0.147273
LRPPRC leucine-rich pentatricopeptide repeat containing 0.145218
CTSC cathepsin C 0.143765
WDR60 WD repeat domain 60 0.14172
COL10A1 collagen, type X, alpha 1 0.141518
NT5DC1 5'-nucleotidase domain containing 1 0.141518
NRG3 neuregulin 3 0.140993
ATRNL1 attractin-like 1 0.134745
CASP5 caspase 5, apoptosis-related cysteine peptidase 0.132686
LHFP lipoma HMGIC fusion partner 0.13115
DDO D-aspartate oxidase 0.129963
NFIB nuclear factor I/B 0.128096
HSPH1 heat shock 105kDa/110kDa protein 1 0.123562
FMN2 formin 2 0.122568
HELZ helicase with zinc finger 0.117437
CHN2 chimerin 2 0.117287
SMOC1 SPARC related modular calcium binding 1 0.115914
AKAP6 A kinase (PRKA) anchor protein 6 0.113894
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.112348
MYO18B myosin XVIIIB 0.108712
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.107404
GIMAP7 GTPase, IMAP family member 7 0.105799
C9ORF84 chromosome 9 open reading frame 84 0.10543
CCND3 cyclin D3 0.104162
DOCK1 dedicator of cytokinesis 1 0.101679
LYN LYN proto-oncogene, Src family tyrosine kinase 0.10157
FAM69C family with sequence similarity 69, member C 0.098312
IL22RA2 interleukin 22 receptor, alpha 2 0.095845
SYN3 synapsin III 0.092922
HDAC4 histone deacetylase 4 0.090332
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.089416
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.08898
PDHX pyruvate dehydrogenase complex, component X 0.088544
PPP1R37 protein phosphatase 1, regulatory subunit 37 0.086954
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase) 0.086808
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.086332
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.084435
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.08379
NDUFB8P3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, pseudogene 3 0.08165
DPYD dihydropyrimidine dehydrogenase 0.080372
SOX2-OT SOX2 overlapping transcript 0.073226
RPL23P9 ribosomal protein L23 pseudogene 9 0.073214
BPGM 2,3-bisphosphoglycerate mutase 0.069489
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.069477
ADAM22 ADAM metallopeptidase domain 22 0.069145
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.067315
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 0.066316
CSMD1 CUB and Sushi multiple domains 1 0.066108
GRID1 glutamate receptor, ionotropic, delta 1 0.065868
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.061362
WDR70 WD repeat domain 70 0.061313
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.060168
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.059243
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.058578
TMEM81 transmembrane protein 81 0.05826