BRD-U94846492_Quinine hemisulfate salt monohydrate_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-U94846492_Quinine hemisulfate salt monohydrate_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND2 cyclin D2
CD163 CD163 molecule
DDIT4 DNA-damage-inducible transcript 4
ECM1 extracellular matrix protein 1
FGFR3 fibroblast growth factor receptor 3
H1F0 H1 histone family, member 0
HMGB3 high mobility group box 3
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INSIG1 insulin induced gene 1
MAOB monoamine oxidase B
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PXMP2 peroxisomal membrane protein 2, 22kDa
TGFBI transforming growth factor, beta-induced, 68kDa
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3

decreased expression

Symbol Name
ALAS1 5'-aminolevulinate synthase 1
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
BHLHE41 basic helix-loop-helix family, member e41
CLIC3 chloride intracellular channel 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
GADD45B growth arrest and DNA-damage-inducible, beta
GPX3 glutathione peroxidase 3
KCTD5 potassium channel tetramerization domain containing 5
KRT7 keratin 7, type II
LAMP5 lysosomal-associated membrane protein family, member 5
PIP prolactin-induced protein
PODXL podocalyxin-like
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SATB1 SATB homeobox 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLPI secretory leukocyte peptidase inhibitor
SOX11 SRY (sex determining region Y)-box 11
TFF1 trefoil factor 1
VAT1 vesicle amine transport 1
VEGFC vascular endothelial growth factor C