BRD-U94846492_Quinine hemisulfate salt monohydrate_MDST8_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-U94846492_Quinine hemisulfate salt monohydrate_MDST8_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP9 aquaporin 9
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
BID BH3 interacting domain death agonist
CCNA1 cyclin A1
CD300A CD300a molecule
CDC20 cell division cycle 20
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIC2 cysteine-rich hydrophobic domain 2
CLU clusterin
CNPY3 canopy FGF signaling regulator 3
COCH cochlin
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
DLK1 delta-like 1 homolog (Drosophila)
F3 coagulation factor III (thromboplastin, tissue factor)
FGF13 fibroblast growth factor 13
FPR1 formyl peptide receptor 1
GCH1 GTP cyclohydrolase 1
GEM GTP binding protein overexpressed in skeletal muscle
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGFBP7 insulin-like growth factor binding protein 7
IL13RA2 interleukin 13 receptor, alpha 2
JAG1 jagged 1
KIF5C kinesin family member 5C
LXN latexin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP7 matrix metallopeptidase 7
MSMB microseminoprotein, beta-
NAMPT nicotinamide phosphoribosyltransferase
NID2 nidogen 2 (osteonidogen)
NTS neurotensin
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE4D phosphodiesterase 4D, cAMP-specific
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTPRO protein tyrosine phosphatase, receptor type, O
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RGS4 regulator of G-protein signaling 4
RPS11 ribosomal protein S11
SCG5 secretogranin V
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SOD2 superoxide dismutase 2, mitochondrial
SORD sorbitol dehydrogenase
STC1 stanniocalcin 1
TLR4 toll-like receptor 4
TMEM158 transmembrane protein 158 (gene/pseudogene)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AARS alanyl-tRNA synthetase
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALAS1 5'-aminolevulinate synthase 1
ARMCX2 armadillo repeat containing, X-linked 2
ASPH aspartate beta-hydroxylase
CAV1 caveolin 1, caveolae protein, 22kDa
CCND1 cyclin D1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLTB clathrin, light chain B
COG7 component of oligomeric golgi complex 7
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCL14 chemokine (C-X-C motif) ligand 14
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
EAPP E2F-associated phosphoprotein
EHD2 EH-domain containing 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOLR1 folate receptor 1 (adult)
GLS glutaminase
HES1 hes family bHLH transcription factor 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI44L interferon-induced protein 44-like
IKZF1 IKAROS family zinc finger 1 (Ikaros)
MEST mesoderm specific transcript
MFAP5 microfibrillar associated protein 5
MGLL monoglyceride lipase
MTDH metadherin
MX1 MX dynamin-like GTPase 1
PEG10 paternally expressed 10
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POSTN periostin, osteoblast specific factor
PRELP proline/arginine-rich end leucine-rich repeat protein
PRODH proline dehydrogenase (oxidase) 1
RGCC regulator of cell cycle
SELENBP1 selenium binding protein 1
SFN stratifin
SFTPB surfactant protein B
SFTPC surfactant protein C
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNIP1 TNFAIP3 interacting protein 1
TNS1 tensin 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIB3 tribbles pseudokinase 3
TUBA4A tubulin, alpha 4a
ZBED2 zinc finger, BED-type containing 2