BRD-U74615290_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-U74615290_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DIO1 deiodinase, iodothyronine, type I
DPH2 DPH2 homolog (S. cerevisiae)
MMP12 matrix metallopeptidase 12
NT5E 5'-nucleotidase, ecto (CD73)
ODC1 ornithine decarboxylase 1
PAK1IP1 PAK1 interacting protein 1
PHACTR1 phosphatase and actin regulator 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PRR7 proline rich 7 (synaptic)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM5 transmembrane protein 5

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AKAP13 A kinase (PRKA) anchor protein 13
ALCAM activated leukocyte cell adhesion molecule
AQP3 aquaporin 3 (Gill blood group)
C3 complement component 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
DHCR24 24-dehydrocholesterol reductase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
KIAA0101 KIAA0101
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LIMA1 LIM domain and actin binding 1
LTF lactotransferrin
MSMO1 methylsterol monooxygenase 1
MYO6 myosin VI
NUSAP1 nucleolar and spindle associated protein 1
PXDN peroxidasin
RND3 Rho family GTPase 3
RNF167 ring finger protein 167
S100A11 S100 calcium binding protein A11
SC5D sterol-C5-desaturase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SQLE squalene epoxidase
TNIP1 TNFAIP3 interacting protein 1
TNS1 tensin 1