BRD-U73238814_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-U73238814_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ARL4C ADP-ribosylation factor-like 4C
CD163 CD163 molecule
COMP cartilage oligomeric matrix protein
CTGF connective tissue growth factor
CX3CR1 chemokine (C-X3-C motif) receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
FCGBP Fc fragment of IgG binding protein
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
LTF lactotransferrin
MTSS1 metastasis suppressor 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SCRG1 stimulator of chondrogenesis 1
TGFBI transforming growth factor, beta-induced, 68kDa

decreased expression

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
HES1 hes family bHLH transcription factor 1
MGLL monoglyceride lipase
MOAP1 modulator of apoptosis 1
NUP85 nucleoporin 85kDa
OGN osteoglycin
SGK1 serum/glucocorticoid regulated kinase 1
TFPI2 tissue factor pathway inhibitor 2
TMEM251 transmembrane protein 251