BRD-U70626184_BI-2536_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-U70626184_BI-2536_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANOS1 anosmin 1
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
BZW2 basic leucine zipper and W2 domains 2
C5 complement component 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHGB chromogranin B
CXADR coxsackie virus and adenovirus receptor
CYCS cytochrome c, somatic
DACH1 dachshund family transcription factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP5 dual specificity phosphatase 5
DYNLT3 dynein, light chain, Tctex-type 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPCAM epithelial cell adhesion molecule
FAM46A family with sequence similarity 46, member A
FOSL2 FOS-like antigen 2
FZD1 frizzled class receptor 1
FZD5 frizzled class receptor 5
GATA3 GATA binding protein 3
GRWD1 glutamate-rich WD repeat containing 1
IRS2 insulin receptor substrate 2
KRT20 keratin 20, type I
LDLR low density lipoprotein receptor
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LXN latexin
LY75 lymphocyte antigen 75
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MT1F metallothionein 1F
NEBL nebulette
NNMT nicotinamide N-methyltransferase
NPTX2 neuronal pentraxin II
NPY1R neuropeptide Y receptor Y1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PLS1 plastin 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RGS2 regulator of G-protein signaling 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3YL1 SH3 and SYLF domain containing 1
SIK1 salt-inducible kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STMN2 stathmin 2
TOX3 TOX high mobility group box family member 3
TPD52 tumor protein D52
TSPAN13 tetraspanin 13
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
ALB albumin
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CD36 CD36 molecule (thrombospondin receptor)
COL5A1 collagen, type V, alpha 1
DMD dystrophin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
FAM69A family with sequence similarity 69, member A
FHL1 four and a half LIM domains 1
GMPR guanosine monophosphate reductase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFI16 interferon, gamma-inducible protein 16
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
LYPD1 LY6/PLAUR domain containing 1
NES nestin
PFN2 profilin 2
PTGIS prostaglandin I2 (prostacyclin) synthase
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
WT1 Wilms tumor 1