BRD-U70626184_BI-2536_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-U70626184_BI-2536_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANOS1 anosmin 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AQP3 aquaporin 3 (Gill blood group)
CD9 CD9 molecule
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGFL6 EGF-like-domain, multiple 6
EZR ezrin
FAM134B family with sequence similarity 134, member B
GDF15 growth differentiation factor 15
GPRC5A G protein-coupled receptor, class C, group 5, member A
HLA-C major histocompatibility complex, class I, C
HLA-F major histocompatibility complex, class I, F
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KDM5D lysine (K)-specific demethylase 5D
KRT13 keratin 13, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LITAF lipopolysaccharide-induced TNF factor
MBP myelin basic protein
MSMB microseminoprotein, beta-
MTSS1 metastasis suppressor 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PRAME preferentially expressed antigen in melanoma
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMAD3 SMAD family member 3
STAT1 signal transducer and activator of transcription 1, 91kDa
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGCG UDP-glucose ceramide glucosyltransferase
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALB albumin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BHLHE41 basic helix-loop-helix family, member e41
CA2 carbonic anhydrase II
CCND1 cyclin D1
CCND2 cyclin D2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CRISP3 cysteine-rich secretory protein 3
CXCL12 chemokine (C-X-C motif) ligand 12
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
DSG1 desmoglein 1
EPHB2 EPH receptor B2
FABP7 fatty acid binding protein 7, brain
FGFR1 fibroblast growth factor receptor 1
HMGA2 high mobility group AT-hook 2
HOMER1 homer scaffolding protein 1
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
JAG1 jagged 1
JMJD6 jumonji domain containing 6
KTN1 kinectin 1 (kinesin receptor)
MARCKS myristoylated alanine-rich protein kinase C substrate
MFAP5 microfibrillar associated protein 5
MGLL monoglyceride lipase
NES nestin
NRN1 neuritin 1
OXTR oxytocin receptor
PADI2 peptidyl arginine deiminase, type II
PELI1 pellino E3 ubiquitin protein ligase 1
PLN phospholamban
PROM1 prominin 1
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
PTHLH parathyroid hormone-like hormone
REG3A regenerating islet-derived 3 alpha
SCG5 secretogranin V
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP1 secreted frizzled-related protein 1
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
TUBB2A tubulin, beta 2A class IIa
VCAN versican
XIST X inactive specific transcript (non-protein coding)
ZBTB18 zinc finger and BTB domain containing 18