BRD-U64521890_XMD16-144_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

56 genes differentially expressed following the BRD-U64521890_XMD16-144_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAV1 caveolin 1, caveolae protein, 22kDa
DAPK1 death-associated protein kinase 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR1 early growth response 1
EGR3 early growth response 3
FLG filaggrin
GATA6 GATA binding protein 6
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HIST1H2BK histone cluster 1, H2bk
HOXA10 homeobox A10
HOXC6 homeobox C6
HSPA2 heat shock 70kDa protein 2
LAMA3 laminin, alpha 3
MT1E metallothionein 1E
NOTCH2 notch 2
NTS neurotensin
RPS4Y1 ribosomal protein S4, Y-linked 1
TFF1 trefoil factor 1

decreased expression

Symbol Name
ANXA3 annexin A3
BASP1 brain abundant, membrane attached signal protein 1
CAST calpastatin
CCL2 chemokine (C-C motif) ligand 2
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CTSB cathepsin B
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DENND2D DENN/MADD domain containing 2D
FAS Fas cell surface death receptor
FKBP11 FK506 binding protein 11, 19 kDa
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GRIA2 glutamate receptor, ionotropic, AMPA 2
HES1 hes family bHLH transcription factor 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGHD immunoglobulin heavy constant delta
IGKV1-5 immunoglobulin kappa variable 1-5
INHBB inhibin, beta B
KRT18 keratin 18, type I
KRT23 keratin 23, type I
KRT7 keratin 7, type II
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTF lactotransferrin
MBOAT2 membrane bound O-acyltransferase domain containing 2
PAX5 paired box 5
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLPI secretory leukocyte peptidase inhibitor
SORBS2 sorbin and SH3 domain containing 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPP1 secreted phosphoprotein 1
TFPI2 tissue factor pathway inhibitor 2
TSKU tsukushi, small leucine rich proteoglycan
VAV3 vav 3 guanine nucleotide exchange factor
VTCN1 V-set domain containing T cell activation inhibitor 1