BRD-U64521890_XMD16-144_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-U64521890_XMD16-144_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACKR3 atypical chemokine receptor 3
AHNAK2 AHNAK nucleoprotein 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAG3 BCL2-associated athanogene 3
CAPN1 calpain 1, (mu/I) large subunit
CCNG1 cyclin G1
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COBL cordon-bleu WH2 repeat protein
DSP desmoplakin
DUSP14 dual specificity phosphatase 14
EGFL6 EGF-like-domain, multiple 6
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FOLR1 folate receptor 1 (adult)
GADD45A growth arrest and DNA-damage-inducible, alpha
HACD1 3-hydroxyacyl-CoA dehydratase 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IER5 immediate early response 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LRRN3 leucine rich repeat neuronal 3
MOK MOK protein kinase
MYOF myoferlin
NEU1 sialidase 1 (lysosomal sialidase)
NT5E 5'-nucleotidase, ecto (CD73)
ORAI3 ORAI calcium release-activated calcium modulator 3
PEG10 paternally expressed 10
PERP PERP, TP53 apoptosis effector
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLK2 polo-like kinase 2
PON2 paraoxonase 2
PPL periplakin
PRUNE2 prune homolog 2 (Drosophila)
RBKS ribokinase
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RHOBTB3 Rho-related BTB domain containing 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SESN1 sestrin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TIMP1 TIMP metallopeptidase inhibitor 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TP53I3 tumor protein p53 inducible protein 3
TP53TG1 TP53 target 1 (non-protein coding)
TRAPPC3 trafficking protein particle complex 3
TRIM22 tripartite motif containing 22
UGDH UDP-glucose 6-dehydrogenase
ZDHHC11 zinc finger, DHHC-type containing 11
ZMAT3 zinc finger, matrin-type 3
ZNF512B zinc finger protein 512B

decreased expression

Symbol Name
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMP cathelicidin antimicrobial peptide
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CLC Charcot-Leyden crystal galectin
CXCL14 chemokine (C-X-C motif) ligand 14
DNASE1L3 deoxyribonuclease I-like 3
EFHD1 EF-hand domain family, member D1
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EXOSC8 exosome component 8
FAR2 fatty acyl CoA reductase 2
GAL galanin/GMAP prepropeptide
GAS1 growth arrest-specific 1
HAL histidine ammonia-lyase
HMGB1 high mobility group box 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
LAMP5 lysosomal-associated membrane protein family, member 5
MGAM maltase-glucoamylase
MKI67 marker of proliferation Ki-67
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
NBL1 neuroblastoma 1, DAN family BMP antagonist
NLRP2 NLR family, pyrin domain containing 2
PMP22 peripheral myelin protein 22
PRPS2 phosphoribosyl pyrophosphate synthetase 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS4 regulator of G-protein signaling 4
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SATB1 SATB homeobox 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SPC25 SPC25, NDC80 kinetochore complex component
TCF4 transcription factor 4
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TMSB15A thymosin beta 15a
TSPAN8 tetraspanin 8
ZBTB18 zinc finger and BTB domain containing 18
ZDHHC6 zinc finger, DHHC-type containing 6
ZWILCH zwilch kinetochore protein