BRD-U64289953_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

58 genes differentially expressed following the BRD-U64289953_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD3 abhydrolase domain containing 3
ACKR3 atypical chemokine receptor 3
AGR2 anterior gradient 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CIRBP cold inducible RNA binding protein
COL14A1 collagen, type XIV, alpha 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
DUSP14 dual specificity phosphatase 14
FADS1 fatty acid desaturase 1
FGFR3 fibroblast growth factor receptor 3
GSTA4 glutathione S-transferase alpha 4
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
KIAA1033 KIAA1033
KLHDC2 kelch domain containing 2
KRT16 keratin 16, type I
LRP4 low density lipoprotein receptor-related protein 4
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPT microtubule-associated protein tau
MSMO1 methylsterol monooxygenase 1
PCDH9 protocadherin 9
PHYH phytanoyl-CoA 2-hydroxylase
PLD3 phospholipase D family, member 3
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ADORA2B adenosine A2b receptor
BHLHE41 basic helix-loop-helix family, member e41
CA12 carbonic anhydrase XII
CP ceruloplasmin (ferroxidase)
DENND2D DENN/MADD domain containing 2D
DPH2 DPH2 homolog (S. cerevisiae)
EGFR epidermal growth factor receptor
EREG epiregulin
JADE2 jade family PHD finger 2
MBNL2 muscleblind-like splicing regulator 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
PLAC8 placenta-specific 8
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TM4SF1 transmembrane 4 L six family member 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit