BRD-U60236422_WH-4-025_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-U60236422_WH-4-025_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
AQP3 aquaporin 3 (Gill blood group)
ARID4B AT rich interactive domain 4B (RBP1-like)
C5 complement component 5
CCDC92 coiled-coil domain containing 92
CD24 CD24 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DSP desmoplakin
DYNLT3 dynein, light chain, Tctex-type 3
EPHA3 EPH receptor A3
ETV1 ets variant 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
G6PD glucose-6-phosphate dehydrogenase
GLRX glutaredoxin (thioltransferase)
HNMT histamine N-methyltransferase
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
KYNU kynureninase
LGALS3 lectin, galactoside-binding, soluble, 3
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LXN latexin
LY96 lymphocyte antigen 96
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MEIS1 Meis homeobox 1
NRCAM neuronal cell adhesion molecule
NRP1 neuropilin 1
PHYH phytanoyl-CoA 2-hydroxylase
PLVAP plasmalemma vesicle associated protein
PPL periplakin
RAB31 RAB31, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBM47 RNA binding motif protein 47
REEP1 receptor accessory protein 1
RGS2 regulator of G-protein signaling 2
S100P S100 calcium binding protein P
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SVIL supervillin
SYNM synemin, intermediate filament protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF1 transmembrane 4 L six family member 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM2 tripartite motif containing 2
TSC22D1 TSC22 domain family, member 1
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADM adrenomedullin
AUTS2 autism susceptibility candidate 2
BTG3 BTG family, member 3
CALD1 caldesmon 1
CCP110 centriolar coiled coil protein 110kDa
CDC45 cell division cycle 45
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
FGFR3 fibroblast growth factor receptor 3
FSD1 fibronectin type III and SPRY domain containing 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HLA-DRA major histocompatibility complex, class II, DR alpha
ICAM2 intercellular adhesion molecule 2
IGFBP3 insulin-like growth factor binding protein 3
IL32 interleukin 32
MGLL monoglyceride lipase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYH10 myosin, heavy chain 10, non-muscle
MYL9 myosin, light chain 9, regulatory
MYLK myosin light chain kinase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P3H2 prolyl 3-hydroxylase 2
PEG3 paternally expressed 3
RRP1B ribosomal RNA processing 1B
SACS sacsin molecular chaperone
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SPP1 secreted phosphoprotein 1
STK10 serine/threonine kinase 10
TAGLN transgelin
THBS1 thrombospondin 1
TRBC1 T cell receptor beta constant 1
TUBB6 tubulin, beta 6 class V