BRD-U60236422_WH-4-025_HEPG2_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-U60236422_WH-4-025_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AIM1 absent in melanoma 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDOB aldolase B, fructose-bisphosphate
CALB1 calbindin 1, 28kDa
CCL20 chemokine (C-C motif) ligand 20
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CP ceruloplasmin (ferroxidase)
CRABP2 cellular retinoic acid binding protein 2
CSTA cystatin A (stefin A)
DEFB1 defensin, beta 1
GLUL glutamate-ammonia ligase
GSTA1 glutathione S-transferase alpha 1
HLA-B major histocompatibility complex, class I, B
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IPO13 importin 13
LAPTM5 lysosomal protein transmembrane 5
LMO2 LIM domain only 2 (rhombotin-like 1)
LPCAT1 lysophosphatidylcholine acyltransferase 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MMP7 matrix metallopeptidase 7
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PRAME preferentially expressed antigen in melanoma
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
S100A8 S100 calcium binding protein A8
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SPINK1 serine peptidase inhibitor, Kazal type 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TKT transketolase
TRIM2 tripartite motif containing 2
USP18 ubiquitin specific peptidase 18
VAT1 vesicle amine transport 1
VTCN1 V-set domain containing T cell activation inhibitor 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
AK1 adenylate kinase 1
CALD1 caldesmon 1
COL1A1 collagen, type I, alpha 1
CSRP1 cysteine and glycine-rich protein 1
DUSP5 dual specificity phosphatase 5
EFNB2 ephrin-B2
EREG epiregulin
IER3 immediate early response 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
MCAM melanoma cell adhesion molecule
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PEG3 paternally expressed 3
PLCB4 phospholipase C, beta 4
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRSS3 protease, serine, 3
RBP1 retinol binding protein 1, cellular
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TAGLN transgelin
TGFBI transforming growth factor, beta-induced, 68kDa