BRD-U60236422_WH-4-025_BT20_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-U60236422_WH-4-025_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
C6ORF62 chromosome 6 open reading frame 62
CCL20 chemokine (C-C motif) ligand 20
CLGN calmegin
CXCL14 chemokine (C-X-C motif) ligand 14
EZR ezrin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IER3 immediate early response 3
KCTD12 potassium channel tetramerization domain containing 12
MALL mal, T-cell differentiation protein-like
PDIA5 protein disulfide isomerase family A, member 5
PTGES prostaglandin E synthase
RBM47 RNA binding motif protein 47
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
XPOT exportin, tRNA
ZBTB18 zinc finger and BTB domain containing 18
ZDHHC6 zinc finger, DHHC-type containing 6

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
C3ORF14 chromosome 3 open reading frame 14
CADM1 cell adhesion molecule 1
CD200 CD200 molecule
CD24 CD24 molecule
CNN1 calponin 1, basic, smooth muscle
COL14A1 collagen, type XIV, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CSRP1 cysteine and glycine-rich protein 1
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDAH1 dimethylarginine dimethylaminohydrolase 1
DMD dystrophin
DSP desmoplakin
EFHD1 EF-hand domain family, member D1
EMP1 epithelial membrane protein 1
F2R coagulation factor II (thrombin) receptor
FAS Fas cell surface death receptor
FERMT2 fermitin family member 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP1 guanylate binding protein 1, interferon-inducible
HMGA2 high mobility group AT-hook 2
HSPA1A heat shock 70kDa protein 1A
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INSIG1 insulin induced gene 1
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT23 keratin 23, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
MAOB monoamine oxidase B
MARCKSL1 MARCKS-like 1
MT1E metallothionein 1E
MYL9 myosin, light chain 9, regulatory
MYOF myoferlin
NID1 nidogen 1
NID2 nidogen 2 (osteonidogen)
NT5DC2 5'-nucleotidase domain containing 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDGFC platelet derived growth factor C
PDLIM1 PDZ and LIM domain 1
PDLIM5 PDZ and LIM domain 5
PIP prolactin-induced protein
PLS3 plastin 3
PTN pleiotrophin
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PXDN peroxidasin
RGS13 regulator of G-protein signaling 13
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFN stratifin
SNAP25 synaptosomal-associated protein, 25kDa
SOX10 SRY (sex determining region Y)-box 10
SOX4 SRY (sex determining region Y)-box 4
TAGLN transgelin
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TMSB15A thymosin beta 15a
TPM1 tropomyosin 1 (alpha)
TUBB6 tubulin, beta 6 class V