BRD-U51024685_HG-6-64-01_MCF7_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-U51024685_HG-6-64-01_MCF7_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
COL11A1 collagen, type XI, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
EGR1 early growth response 1
EGR3 early growth response 3
EMP3 epithelial membrane protein 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GSTM3 glutathione S-transferase mu 3 (brain)
HBB hemoglobin, beta
IGFBP7 insulin-like growth factor binding protein 7
KIF5C kinesin family member 5C
MEF2C myocyte enhancer factor 2C
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RTN1 reticulon 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOX11 SRY (sex determining region Y)-box 11
SPP1 secreted phosphoprotein 1
SRGN serglycin
TGFBI transforming growth factor, beta-induced, 68kDa
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UGCG UDP-glucose ceramide glucosyltransferase
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADCK3 aarF domain containing kinase 3
ATP10B ATPase, class V, type 10B
CADM1 cell adhesion molecule 1
CFB complement factor B
CKB creatine kinase, brain
CLDN10 claudin 10
COL9A3 collagen, type IX, alpha 3
CP ceruloplasmin (ferroxidase)
DMBT1 deleted in malignant brain tumors 1
EML1 echinoderm microtubule associated protein like 1
EPCAM epithelial cell adhesion molecule
EPHA3 EPH receptor A3
FAM13A family with sequence similarity 13, member A
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGA2 high mobility group AT-hook 2
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
JCHAIN joining chain of multimeric IgA and IgM
KIAA0125 KIAA0125
MUC5B mucin 5B, oligomeric mucus/gel-forming
PDZK1IP1 PDZK1 interacting protein 1
PELI1 pellino E3 ubiquitin protein ligase 1
PLS3 plastin 3
RBP4 retinol binding protein 4, plasma
SATB2 SATB homeobox 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SYNGR3 synaptogyrin 3