BRD-U51024685_HG-6-64-01_MCF10A_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-U51024685_HG-6-64-01_MCF10A_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANXA1 annexin A1
ASPN asporin
BMP7 bone morphogenetic protein 7
CCNG2 cyclin G2
CD93 CD93 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL15A1 collagen, type XV, alpha 1
COL3A1 collagen, type III, alpha 1
COL6A3 collagen, type VI, alpha 3
CPVL carboxypeptidase, vitellogenic-like
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
EFHD1 EF-hand domain family, member D1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXA5 homeobox A5
IGFBP5 insulin-like growth factor binding protein 5
KLF4 Kruppel-like factor 4 (gut)
KRT15 keratin 15, type I
KRT19 keratin 19, type I
LXN latexin
MT1F metallothionein 1F
MT1M metallothionein 1M
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PECAM1 platelet/endothelial cell adhesion molecule 1
PHGDH phosphoglycerate dehydrogenase
POSTN periostin, osteoblast specific factor
PROM1 prominin 1
PSAT1 phosphoserine aminotransferase 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS2 regulator of G-protein signaling 2
SPRED2 sprouty-related, EVH1 domain containing 2
TSC22D3 TSC22 domain family, member 3
TSPYL5 TSPY-like 5
TUBB6 tubulin, beta 6 class V
TXNIP thioredoxin interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VCAN versican
XBP1 X-box binding protein 1

decreased expression

Symbol Name
C1ORF116 chromosome 1 open reading frame 116
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
EGR3 early growth response 3
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
HMGA2 high mobility group AT-hook 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
JMJD6 jumonji domain containing 6
KRT17 keratin 17, type I
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1