BRD-U51024685_HG-6-64-01_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

126 genes differentially expressed following the BRD-U51024685_HG-6-64-01_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AIF1 allograft inflammatory factor 1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD36B ankyrin repeat domain 36B
ANXA4 annexin A4
BASP1 brain abundant, membrane attached signal protein 1
BLVRB biliverdin reductase B
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAPG capping protein (actin filament), gelsolin-like
CD24 CD24 molecule
CFD complement factor D (adipsin)
COL4A5 collagen, type IV, alpha 5
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DPP4 dipeptidyl-peptidase 4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
F13A1 coagulation factor XIII, A1 polypeptide
FCGBP Fc fragment of IgG binding protein
FOXO4 forkhead box O4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
MAOA monoamine oxidase A
MARCKS myristoylated alanine-rich protein kinase C substrate
MATN2 matrilin 2
MBP myelin basic protein
MFAP5 microfibrillar associated protein 5
MLPH melanophilin
MME membrane metallo-endopeptidase
MPPED2 metallophosphoesterase domain containing 2
MT1F metallothionein 1F
MT1X metallothionein 1X
MUC5B mucin 5B, oligomeric mucus/gel-forming
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NUPR1 nuclear protein, transcriptional regulator, 1
OSBPL1A oxysterol binding protein-like 1A
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PHGDH phosphoglycerate dehydrogenase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PINK1 PTEN induced putative kinase 1
PLAC8 placenta-specific 8
PPAP2B phosphatidic acid phosphatase type 2B
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPL periplakin
PRSS23 protease, serine, 23
QPRT quinolinate phosphoribosyltransferase
RAP1GAP RAP1 GTPase activating protein
RBKS ribokinase
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SIDT2 SID1 transmembrane family, member 2
SORBS1 sorbin and SH3 domain containing 1
SOX4 SRY (sex determining region Y)-box 4
TPP1 tripeptidyl peptidase I
TSC22D3 TSC22 domain family, member 3
TST thiosulfate sulfurtransferase (rhodanese)
TXNIP thioredoxin interacting protein
VAMP8 vesicle-associated membrane protein 8
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMIGO2 adhesion molecule with Ig-like domain 2
AREG amphiregulin
BICD2 bicaudal D homolog 2 (Drosophila)
BUB3 BUB3 mitotic checkpoint protein
CCNF cyclin F
CDC25A cell division cycle 25A
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COMP cartilage oligomeric matrix protein
CSTA cystatin A (stefin A)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
EGR2 early growth response 2
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EREG epiregulin
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GTPBP8 GTP-binding protein 8 (putative)
HOPX HOP homeobox
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPH1 heat shock 105kDa/110kDa protein 1
IER3 immediate early response 3
IFI16 interferon, gamma-inducible protein 16
IGFBP7 insulin-like growth factor binding protein 7
KCTD12 potassium channel tetramerization domain containing 12
KIAA0020 KIAA0020
LDHB lactate dehydrogenase B
MAPK13 mitogen-activated protein kinase 13
MELK maternal embryonic leucine zipper kinase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NRN1 neuritin 1
ODC1 ornithine decarboxylase 1
PLK1 polo-like kinase 1
PNP purine nucleoside phosphorylase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RPIA ribose 5-phosphate isomerase A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SORD sorbitol dehydrogenase
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STK17A serine/threonine kinase 17a
TFPI2 tissue factor pathway inhibitor 2
TFRC transferrin receptor
UBE2S ubiquitin-conjugating enzyme E2S
WNT5A wingless-type MMTV integration site family, member 5A