BRD-U44700465_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-U44700465_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD99 CD99 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
FAM117A family with sequence similarity 117, member A
G6PD glucose-6-phosphate dehydrogenase
GPATCH8 G patch domain containing 8
HOXB2 homeobox B2
KDM3A lysine (K)-specific demethylase 3A
LTF lactotransferrin
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
ORAI3 ORAI calcium release-activated calcium modulator 3
PBX1 pre-B-cell leukemia homeobox 1
RGCC regulator of cell cycle
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
TACSTD2 tumor-associated calcium signal transducer 2
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ARPC5L actin related protein 2/3 complex, subunit 5-like
C6ORF62 chromosome 6 open reading frame 62
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP7 dual specificity phosphatase 7
FABP1 fatty acid binding protein 1, liver
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IDI1 isopentenyl-diphosphate delta isomerase 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
PAK1IP1 PAK1 interacting protein 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PPIF peptidylprolyl isomerase F
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PTGDS prostaglandin D2 synthase 21kDa (brain)
RBM34 RNA binding motif protein 34
SFPQ splicing factor proline/glutamine-rich
TFPI2 tissue factor pathway inhibitor 2
TXNDC9 thioredoxin domain containing 9
UFM1 ubiquitin-fold modifier 1