BRD-U44700465_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-U44700465_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
AQP3 aquaporin 3 (Gill blood group)
CCNG2 cyclin G2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CENPE centromere protein E, 312kDa
CPA3 carboxypeptidase A3 (mast cell)
DDAH2 dimethylarginine dimethylaminohydrolase 2
EDN1 endothelin 1
EFNA1 ephrin-A1
ERBB2 erb-b2 receptor tyrosine kinase 2
FHL1 four and a half LIM domains 1
FOXO4 forkhead box O4
GATA2 GATA binding protein 2
GNB5 guanine nucleotide binding protein (G protein), beta 5
GRN granulin
GSDMB gasdermin B
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOPX HOP homeobox
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
JUP junction plakoglobin
KCNK1 potassium channel, two pore domain subfamily K, member 1
MAOA monoamine oxidase A
MFAP5 microfibrillar associated protein 5
MYO6 myosin VI
NDRG1 N-myc downstream regulated 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PPL periplakin
RAB25 RAB25, member RAS oncogene family
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100P S100 calcium binding protein P
SOX4 SRY (sex determining region Y)-box 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)

decreased expression

Symbol Name
CPE carboxypeptidase E
EIF5 eukaryotic translation initiation factor 5
FOSL1 FOS-like antigen 1
GRWD1 glutamate-rich WD repeat containing 1
IL13RA2 interleukin 13 receptor, alpha 2
JMJD6 jumonji domain containing 6
KCTD12 potassium channel tetramerization domain containing 12
NOLC1 nucleolar and coiled-body phosphoprotein 1
ODC1 ornithine decarboxylase 1
PNN pinin, desmosome associated protein
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP3 STEAP family member 3, metalloreductase
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TMEM70 transmembrane protein 70