BRD-U33728988_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-U33728988_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
AOX1 aldehyde oxidase 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATF3 activating transcription factor 3
CD24 CD24 molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLU clusterin
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DUSP4 dual specificity phosphatase 4
FAM63A family with sequence similarity 63, member A
FOXO1 forkhead box O1
FOXO3 forkhead box O3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATA3 GATA binding protein 3
H2BFS H2B histone family, member S (pseudogene)
HBP1 HMG-box transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
HIST1H2BI histone cluster 1, H2bi
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HIST1H4H histone cluster 1, H4h
IER3 immediate early response 3
IRS2 insulin receptor substrate 2
KLF6 Kruppel-like factor 6
MTSS1 metastasis suppressor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDK4 pyruvate dehydrogenase kinase, isozyme 4
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RIOK3 RIO kinase 3
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SORBS2 sorbin and SH3 domain containing 2
SOX4 SRY (sex determining region Y)-box 4
SRSF7 serine/arginine-rich splicing factor 7
SYT1 synaptotagmin I
TBX3 T-box 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
TXNL4B thioredoxin-like 4B
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ANXA11 annexin A11
CACYBP calcyclin binding protein
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDC25A cell division cycle 25A
CLDN10 claudin 10
COL3A1 collagen, type III, alpha 1
CSRP2 cysteine and glycine-rich protein 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP7 dual specificity phosphatase 7
ECM1 extracellular matrix protein 1
FOXF1 forkhead box F1
FXYD5 FXYD domain containing ion transport regulator 5
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNB5 guanine nucleotide binding protein (G protein), beta 5
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
INSIG1 insulin induced gene 1
LARP1 La ribonucleoprotein domain family, member 1
MAT2A methionine adenosyltransferase II, alpha
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MREG melanoregulin
MSMO1 methylsterol monooxygenase 1
MYH10 myosin, heavy chain 10, non-muscle
NR2F6 nuclear receptor subfamily 2, group F, member 6
NT5DC2 5'-nucleotidase domain containing 2
PHLDA2 pleckstrin homology-like domain, family A, member 2
PODXL podocalyxin-like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RCAN2 regulator of calcineurin 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNN stannin
TBC1D16 TBC1 domain family, member 16
TFDP1 transcription factor Dp-1
TKT transketolase
TPM4 tropomyosin 4
TRAPPC3 trafficking protein particle complex 3
TSPAN12 tetraspanin 12
TUBA4A tubulin, alpha 4a
WWC1 WW and C2 domain containing 1