BRD-U33728988_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-U33728988_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP1 aquaporin 1 (Colton blood group)
ARID4B AT rich interactive domain 4B (RBP1-like)
ATF3 activating transcription factor 3
C8ORF4 chromosome 8 open reading frame 4
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFI complement factor I
CLEC2B C-type lectin domain family 2, member B
DAZAP2 DAZ associated protein 2
DCLK1 doublecortin-like kinase 1
DCN decorin
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EGR3 early growth response 3
EPCAM epithelial cell adhesion molecule
ERBB3 erb-b2 receptor tyrosine kinase 3
F13A1 coagulation factor XIII, A1 polypeptide
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
H1F0 H1 histone family, member 0
HAL histidine ammonia-lyase
HIST1H2AC histone cluster 1, H2ac
HIST1H2BC histone cluster 1, H2bc
HOPX HOP homeobox
HOXA5 homeobox A5
HOXC6 homeobox C6
HOXD1 homeobox D1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JUN jun proto-oncogene
KIAA0355 KIAA0355
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
MDK midkine (neurite growth-promoting factor 2)
NR4A2 nuclear receptor subfamily 4, group A, member 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RIOK3 RIO kinase 3
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100P S100 calcium binding protein P
SFRP4 secreted frizzled-related protein 4
TACSTD2 tumor-associated calcium signal transducer 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TXNIP thioredoxin interacting protein
WT1 Wilms tumor 1
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
AHCYL1 adenosylhomocysteinase-like 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
B3GNT1
BEX1 brain expressed, X-linked 1
CALD1 caldesmon 1
CD24 CD24 molecule
CDC25A cell division cycle 25A
CNN3 calponin 3, acidic
CRNN cornulin
CTSZ cathepsin Z
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ECM1 extracellular matrix protein 1
EMP3 epithelial membrane protein 3
FGFR4 fibroblast growth factor receptor 4
GAS1 growth arrest-specific 1
GPC4 glypican 4
GSPT1 G1 to S phase transition 1
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT4 keratin 4, type II
KRT5 keratin 5, type II
METRN meteorin, glial cell differentiation regulator
NEBL nebulette
NRCAM neuronal cell adhesion molecule
PDE4DIP phosphodiesterase 4D interacting protein
PEG10 paternally expressed 10
PGAM1 phosphoglycerate mutase 1 (brain)
PRKCB protein kinase C, beta
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TARS threonyl-tRNA synthetase
THAP11 THAP domain containing 11
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TSKU tsukushi, small leucine rich proteoglycan
TWIST1 twist family bHLH transcription factor 1